Yoichi Kirihara  Hiroshi Nakashima  Toshiya Sanami  Yoshihito Namito  Toshiro Itoga  Shuji Miyamoto 《Journal of Nuclear Science and Technology》2020,57(4):444-456

ABSTRACT

The neutron-emission spectrum from a 197Au target excited with a 16.6 ±0.2 MeV, monoenergetic, linearly polarized photon beam was measured using the time-of-flight method at the NewSUBARU-BL01. Two components were clearly detected in the neutron spectrum produced by photonuclear reactions. One component [component (A)] shows an evaporation-like spectrum with energies up to 4 MeV. The spectrum of the other component [component (B)] is shaped like a bump and energies ≥4 MeV. The intensity of the component (A) does not show any definite angular dependence, whereas, that of the component (B) follows the relation [a+ b cos(2Θ)] as a function of the angle Θ between the polarization and detector directions.  相似文献   

    

Akira Kaieda  Dr. Masashi Takahashi  Hiromi Fukuda  Dr. Rei Okamoto  Dr. Shinji Morimoto  Dr. Masayuki Gotoh  Dr. Takahiro Miyazaki  Yuri Hori  Satoko Unno  Dr. Tomohiro Kawamoto  Dr. Toshimasa Tanaka  Dr. Sachiko Itono  Dr. Terufumi Takagi  Dr. Hiroshi Sugimoto  Dr. Kengo Okada  Dr. Gyorgy Snell  Dr. Ryan Bertsch  Dr. Jasmine Nguyen  Dr. Bi-Ching Sang  Dr. Seiji Miwatashi 《ChemMedChem》2019,14(10):1022-1030

We identified a lead series of p38 mitogen-activated protein kinase inhibitors using a structure-based design strategy from high-throughput screening of hit compound 1 . X-ray crystallography of 1 with the kinase showed an infrequent flip of the peptide bond between Met109 and Gly110, which was considered to lead to high kinase selectivity. Our structure-based design strategy was to conduct scaffold transformation of 1 with maintenance of hydrogen bond interactions with the flipped hinge backbone of the enzyme. In accordance with this strategy, we focused on scaffold transformation to identify imidazo[4,5-b]pyridin-2-one derivatives as potent inhibitors of the p38 MAP kinase. Of the compounds evaluated, 21 was found to be a potent inhibitor of the p38 MAP kinase, lipopolysaccharide-induced tumor necrosis factor-α (TNF-α) production in human monocytic leukemia cells, and TNF-α-induced production of interleukin-8 in human whole blood cells. Herein we describe the discovery of potent and orally bioavailable imidazo[4,5-b]pyridin-2-one-based p38 MAP kinase inhibitors that suppressed cytokine production in a human whole blood cell-based assay.  相似文献   

    

Yuning Zhang  Yoichi Miyahara  Nassim Derriche  Wayne Yang  Khadija Yazda  Xavier Capaldi  Zezhou Liu  Peter Grutter  Walter Reisner 《Small Methods》2019,3(7)

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Fumiaki Yamada  Hajime Nakamura  Yoshitami Sakaguchi  Yoichi Taira 《Journal of the Society for Information Display》2002,10(1):81-85

We have fabricated a 13.3‐in. XGA (1024 × 768) TFT sequential‐color liquid‐crystal display using optically compensated birefringency (OCB), illuminated by an LED backlight. We fabricated the sequential‐color display feasible process technology, and examined the performance and potential of a field‐sequential‐color scheme. The display was connected to a laptop computer and examined for flicker.  相似文献   

    

Yoichi Sato  Kimio Amemiya  Masataka Uchidoi 《Journal of the Society for Information Display》2002,10(1):17-23

This paper will describe the R&D history of color plasma displays (PDPs) at Pioneer. The goals of device performance for color PDPs compared to those of CRTs will be described. The device performance includes luminance, contrast ratio, resolution, gray scale, dynamic false contours, and image quality. In order to improve the device performance described above, the technologies developed by Pioneer will be described. These include T‐shaped electrode, WAFFLE rib structure, CLEAR driving method, and high‐quality video processing. Finally, the next generation of color PDPs will be described in terms of device performance and new technologies.  相似文献   

    

Yasuhiro Yoshida  Yoichi Yamamoto  Masaya Hijikigawa 《Journal of the Society for Information Display》2001,9(4):325-330

We have investigated the color management, in terms of the color adoption property of the human visual system, of a reflective‐type TFT‐LCD (R‐LCD). Since the R‐LCD depends on ambient light as the light source, it is expected that the colorimetric color on the R‐LCD must be changed if the source of the ambient light is changed. However, due to the adaptation property of the human visual system, the eye does not perceive colorimetrically corrected colors as the same color even for an R‐LCD. In this research, first, we conducted a subjective experiment to obtain the RGB code value that is required in order to display a corresponding color on the R‐LCD under varying ambient‐light conditions. The result of the experiment shows that the corresponding color of the experimental results was reasonably approximated by the color obtained by using the von Kries model. Secondly, we proposed a color‐compensating mechanism that is described as a cascaded simple 3 × 3 linear matrix. Actual colors displayed are adjusted according to the ambient light. The evaluation of the picture quality of the R‐LCD showed that the proposed model is effective.  相似文献   

    

Tsuyoshi Id  Hidetoshi Numata  Yoichi Taira  Hideyuki Mizuta  Masaru Suzuki  Michikazu Noguchi  Yoshihiro Katsu 《Journal of the Society for Information Display》2003,11(4):659-665

Abstract— This paper reports on a novel theoretical approach to generate irregular dot patterns at the back of the light guide of a backlight unit. By applying this approach to a light guide with a diffuser film, optical distortion is minimized and the luminance uniformity of the backlight is greatly improved.  相似文献   

    

A Inouye  Y Shinagawa  S Masumura  S Hori  A Irimaziri  S Yahara 《Journal of electron microscopy》1964,13(3):113-118

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Hori  T. 《Electron Devices, IEEE Transactions on》1990,37(9):2058-2069

A comprehensive study on the inversion layer mobility improvement of n-channel MOSFETs with nanometer-range ultra-thin (reoxidized) nitrided oxides is presented. The performance improvement is described from both the device physics modeling and device/circuit design points of view by using the various kinds of current drivability and mobility data over wide ranges of gate drive and E_eff. The nitridation- and reoxidation-condition dependencies of the mobility values are extensively reported. A mechanism for improvement is discussed in conjunction with the observed results of Auger electron spectroscopy, capacitance-voltage measurements, hole mobility measurements of p-channel MOSFETs, and transmission electron microscopy. The (reoxidized) nitrided oxides were fabricated fully by rapid thermal processing instead of conventional quartz-tube furnace annealing, whose major drawback is a considerable redistribution of dopant impurities  相似文献   

    

W Yamamoto  T Hori 《Computers and biomedical research》1970,3(6):699-717

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