This study reports on the analysis of vehicle deformation due to rollover using multi-body dynamics which enables estimating motions of rigid bodies subjected to external forces. For the vehicle rollover analysis using the ADAMS, we have developed a FEA-based numerical vehicle model consisting of a rigid lower body and a deformable upper body. Here, comprehensive analysis of the static and dynamic roof strength resistance of a vehicle using our prediction model is described. We obtain the displacement of A-pillar top-end of a vehicle for each of the static and dynamic tests according to the FMVSS 216 protocol and the Controlled rollover impact system (CRIS) condition, respectively. The displacement of A-pillar top-end represents the roof intrusion causing injuries for passengers in the front seats, thereby evaluating the Strength to weight ratio (SWR) of a vehicle.
Manufacturing industries have recently promoted smart manufacturing (SM) for achieving intelligence, connectedness, and responsiveness of manufacturing objects consisting of man, machine, and material. Traditional manufacturing platforms, which identify generic frameworks where common functionalities are shareable and diverse applications are workable, mainly focused on remote collaboration, distributed control, and data integration; however, they are limited to incorporating those characteristic achievements. The present work introduces an SM-toward manufacturing platform. The proposed platform incorporates the capabilities of (1) virtualization of manufacturing objects for their autonomy and cooperation, (2) processing of real and various manufacturing data for mediating physical and virtual objects, and (3) data-driven decision-making for predictive planning on those objects. For such capabilities, the proposed platform advances the framework of Holonic Manufacturing Systems with the use of agent technology. It integrates a distributed data warehouse to encompass data specification, storage, processing, and retrieval. It applies a data analytics approach to create empirical decision-making models based on real and historical data. Furthermore, it uses open and standardized data interfaces to embody interoperable data exchange across shop floors and manufacturing applications. We present the architecture and technical methods for implementing the proposed platform. We also present a prototype implementation to demonstrate the feasibility and effectiveness of the platform in energy-efficient machining. 相似文献
Eu2+‐doped zinc fluoro‐phosphate Zn2[PO4]F was synthesized by the conventional high‐temperature solid‐state reaction. The phase formation was confirmed by X‐ray powder diffraction measurements and the structure refinement. The photoluminescence excitation and emission spectra, and the decay curves were measured. The natures of the Eu2+ emission in inorganic hosts, e.g., the emission and excitation properties, the chromaticity coordinates, the Stokes shifts, the absolute quantum efficiency, and the luminescence thermal stability were reported. Under the excitation of near‐UV light, Eu2+‐doped Zn2[PO4]F presents a narrow blue‐emitting band centered at 423 nm. The thermal stability of the blue luminescence was evaluated by the luminescence intensities as a function of temperature. The phosphor shows an excellent thermal stability on temperature quenching effects. 相似文献
Dielectric and piezoelectric properties of CuO‐added KNbO3 (KN) ceramics were investigated. The CuO reacted with the Nb2O5, formed a CuO–Nb2O5‐related liquid phase during the sintering, and assisted the densification of the KN ceramics at low temperatures. Moreover, some of the Cu2+ ions replaced the Nb5+ ions in the matrix and behaved as a hardener. The dielectric and piezoelectric properties of the KN ceramics were considerably influenced by the relative density. The 1.0 mol% CuO‐added KN ceramic sintered at 960°C for 1.0 h, which showed a maximum relative density, exhibited a high phase angle of 86.9°, Pr of 14.8 μC/cm2, and Ec of 1.8 kV/mm. This specimen also exhibited good dielectric and piezoelectric properties: εT33/εo of 364, d33 of 122 pC/N, kp of 0.29, and Qm of 611. 相似文献
In this study, the rubber forming process is used to fabricate a micro‐channel titanium plate for a PEM fuel cell. The micro‐channel plate is fabricated using a 200 ton hydraulic press, and various parameters (punch speed, press pressure, rubber thickness, rubber hardness) are investigated in order to evaluate the formability. TiN films are deposited by reactive DC magnetron sputtering (DCMS) with an electromagnetic field system (EMFS). For the uncoated titanium and TiN‐coated titanium substrates, the hardness, surface roughness, and corrosion resistance are estimated by nano‐indentation and electrochemical methods, respectively. The improved corrosion resistance of the TiN films can be attributed to the densification of the film caused by enhancement of nitrification with increasing high reactive nitrogen radicals. The uncoated titanium and TiN‐coated titanium bipolar plates are combined with a unit cell for a performance test, and respective current densities of 0.396 and 0.888 A cm−2 at 0.6 V are obtained. 相似文献
Human umbilical-cord-derived mesenchymal stem cells (hUC-MSC) are a type of mesenchymal stem cells and are more primitive than other MSCs. In this study, we identify novel genes and signal-activating proteins involved in the neural differentiation of hUC-MSCs induced by Low-Intensity Sub-Sonic Vibration (LISSV). RNA sequencing was used to find genes involved in the differentiation process by LISSV. The changes in hUC-MSCs caused by LISSV were confirmed by PLXNA4 overexpression and gene knockdown through small interfering RNA experiments. The six genes were increased among genes related to neurons and the nervous system. One of them, the PLXNA4 gene, is known to play a role as a guide for axons in the development of the nervous system. When the PLXNA4 recombinant protein was added, neuron-related genes were increased. In the PLXNA4 gene knockdown experiment, the expression of neuron-related genes was not changed by LISSV exposure. The PLXNA4 gene is activated by sema family ligands. The expression of SEMA3A was increased by LISSV, and its downstream signaling molecule, FYN, was also activated. We suggest that the PLXNA4 gene plays an important role in hUC-MSC neuronal differentiation through exposure to LISSV. The differentiation process depends on SEMA3A-PLXNA4-dependent FYN activation in hUC-MSCs. 相似文献
Inflammasomes are a group of intracellular multiprotein platforms that play important roles in immune systems. Benzyl isothiocyanate (BITC) is a constituent of cruciferous plants and has been confirmed to exhibit various biological activities. The modulatory effects of BITC on inflammasome-mediated interleukin (IL)-1β expression and its regulatory mechanisms in Pseudomonas aeruginosa (P. aeruginosa) LPS/ATP-stimulated THP-1 cells was investigated. Monocytic THP-1 cells were treated with phorbol myristate acetate (PMA) to induce differentiation into macrophages. Enzyme-linked immunosorbent assays (ELISA) were performed to measure the levels of IL-1β produced in P. aeruginosa LPS/ATP-exposed THP-1 cells. Western blotting was performed to examine the BITC modulatory mechanisms in inflammasome-mediated signaling pathways. BITC inhibited IL-1β production in P. aeruginosa LPS/ATP-induced THP-1 cells. BITC also inhibited activation of leucine-rich repeat protein-3 (NLRP3) and caspase-1 in P. aeruginosa LPS/ATP-induced THP-1 cells. Furthermore, we show that mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) activation in P. aeruginosa LPS was attenuated by BITC. These BITC-mediated modulatory effects on IL-1β production may have therapeutic potential for inflammasome-mediated disorders such as a nasal polyp. 相似文献