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81.
82.
OBJECTIVE: To determine the differential effects of parental major depression (MDD) on psychopathology of childhood, adolescent, and early-adult onset in offspring. METHOD: One hundred eighty-two offspring from 91 families in which one or more parents or neither parent had MDD were followed for more than 10 years and blindly reassessed by means of a structured diagnostic instrument. RESULTS: Parental MDD is associated with increased risk in offspring of childhood-onset MDD (eightfold), anxiety disorder (threefold), conduct disorder (fivefold), and early-adult-onset MDD (fivefold) but not adolescent-onset MDD, where there is a marked increase in risk, particularly in girls, regardless of parental diagnosis. These findings were not explained by parental comorbidity, but the association with MDD was explained by parental age at onset of MDD--there was a 13-fold increase in childhood-onset MDD and a 7-fold increase in adult-onset MDD in offspring of parents with MDD of early (before age 30 years) onset. CONCLUSION: Childhood- and early-adult-onset MDD may be etiologically homogeneous and familial subtypes. The reason for the high incidence of adolescent-onset MDD, particularly in girls, regardless of parental diagnosis, needs to be determined. The childhood offspring of depressed parents are a potential target for evaluation, especially when the parent had an early-onset depression.  相似文献   
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84.
Duplication of the stomach is a rare congenital disease of the childhood. We report the exceptional manifestation in two adults. The clinical presentation and developmental theory is discussed by reviewing the literature. Today the therapy of choice is resection of the duplication with removal of the adjacent wall of the stomach.  相似文献   
85.
A new apparatus has been constructed in which ultrasonic velocity and attenuation coefficients can be measured under oscillatory deformation. Using this apparatus, dynamic ultrasonic parameters were obtained with sufficient accuracy to investigate plastic deformation directly. It is found that this method has potential as a new tool for the study of solid polymers during deformation.  相似文献   
86.
It is important to grasp the explosion characteristics of object gases: natural gas and methane, in order to evaluate the influence of a gas explosion accident in the HTTR hydrogen production system on the reactor. Thus, we carried out explosion experiments of the object gases in semi-open space, and verified a numerical analysis code for the simulation of the explosion accident. It was confirmed that NG–air mixture or methane-air mixture in semi-open space did not result in DDT although 10 g of C-4 explosive was used as an ignition source, and the numerical results agreed relatively with the experimental results. As a result, we could have the prospects for predicting the influence of the explosion accident on the reactor.  相似文献   
87.
The inhibition of hydration of maltal (alpha-D-glucopyranosyl-(1-->4)-2-deoxy-D-glucal) catalyzed by soybean beta-amylase with 4-O-alpha-D-glucopyranosyl-(1-->4)-1-deoxynojirimycin (GDN) was investigated at 25 degrees C and at pH 5.4. As the concentrations of GDN used were comparable to that of the enzyme, Henderson's treatment was applied to this system. It was found that two maltal molecules bind to the enzyme according to a random mechanism and GDN inhibits the hydration of maltal competitively at subsites 1 and 2, and noncompetitively at the other site. On the basis of this result, it was inferred that the role of the mobile loop of this enzyme is to create a convenient catalytic environment for the hydration, and the closing of the active site by the mobile loop is induced by the binding of maltal.  相似文献   
88.
This paper presents an application of parallel genetic algorithms (PGA) to the optimal long-range generation expansion planning. The problem can be formulated as a combinatorial optimization problem that determines the order of introduced generation units at each interval of the year. The proposed method considers introduced power limits of each technology, maximum loads at each interval, and load duration curves at each interval. Appropriate string representation for the problem is presented. Binary and decimal coding and three selection methods are compared. The method is developed on a transputer that is one of the parallel processors. The feasibility of the proposed method is demonstrated using a typical expansion problem with four technologies and five intervals. The method is then compared with conventional dynamic programming and a simple genetic algorithm with promising results.  相似文献   
89.
The effect of the addition of silica particles on spherulite growth rates of isotactic polypropylene has been investigated using an optical microscope. The spherulite growth rate remained constant with time and the growth rates decreased with increasing the silica content. The addition of silica particles generally causes a reduction of the average distance between adjacent silica particles and the linear growth rates become zero when the inter-particle distance reached to the end-to-end distance of the matrix chains. The reduction in the linear growth rate can be explained by assuming the lamellar clustering process that the precursor or solidified units with the single chain space, which spontaneously are built up from the melt, act as the crystallizing units and the diffusive mobility of the units was restricted by spatial confinement between adjacent silica particles.  相似文献   
90.
1IntroductionCharacterswerecreatedasamediumofcommunication.Forexample,theyhavebeenusedtorecordsocialactivitiesandhumanthinking,andtohelppeoplesexchangeinformation.Differencesfrommanyothercharacters,however,theChi-nesecharacterisatypicalideograph.BecauseChinesecharactersoriginatedfromdrawings,theirshapeshavetheelementsofbeauty.InChina,calligraphyaboutChinesecharactershasbeenanimportanpartofartsinceancienttimes.There-sultsofstudiesaboutcalligraphyhavebeenbequeathedascalligraphicworksandcallig…  相似文献   
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