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921.
A novel single-layer, proximity-fed technique for a slot-coupled circularly polarised square patch antenna operated in the ultra-high frequency band is presented. In the proposed design a pair of radiating square patches with a cross-slot and a microstrip feed line are both etched on the top of a microwave substrate, and a coupling arrowshaped slot is etched on the bottom of this substrate. Simulated and measured results indicate that the proposed structure can achieve circular polarisation operation. Proper adjustment of the feed coupling gap distance between the patch and the feed line results in good impedance matching and circularly polarised radiation, and an impedance bandwidth (VSWR <= 2) of about 3.74% and a 3 dB axial-ratio bandwidth of about 1.62% were obtained.  相似文献   
922.
The SARS-CoV-2 pseudovirus is a commonly used strategy that mimics certain biological functions of the authentic virus by relying on biological legitimacy at the molecular level. Despite the fact that spike (S), envelope (E), and membrane (M) proteins together wrap up the SARS-CoV-2 virion, most of the reported pseudotype viruses consist of only the S protein. Here, we report that the presence of E and M increased the virion infectivity by promoting the S protein priming. The S, E, and M (SEM)-coated pseudovirion is spherical, containing crown-like spikes on the surface. Both S and SEM pseudoviruses packaged the same amounts of viral RNA, but the SEM virus bound more efficiently to cells stably expressing the viral receptor human angiotensin-converting enzyme II (hACE2) and became more infectious. Using this SEM pseudovirus, we examined the infectivity and antigenic properties of the natural SARS-CoV-2 variants. We showed that some variants have higher infectivity than the original virus and that some render the neutralizing plasma with lower potency. These studies thus revealed possible mechanisms of the dissemination advantage of these variants. Hence, the SEM pseudovirion provides a useful tool to evaluate the viral infectivity and capability of convalescent sera in neutralizing specific SARS-CoV-2 S dominant variants.  相似文献   
923.
The anode-supported single cell was constructed with porous Ni-Yittria-stabilized zirconia (YSZ) as the anode substrate, an airtight YSZ as the electrolyte, and a screen-printed La0.8Sr0.2MnO3−δ (LSM)-Gadolinia-doped ceria (GDC)/LSM double-layer cathode. The SEM results show that the YSZ thin film is highly integrated, fully dense with a thickness of 13 μm, and exhibits excellent compatibility between cathode and electrolyte layers. The effects of feed rates of the reactants, temperature, and contact pressure between the current collector and the unit cell were systematically investigated. The results are based on the assumption that the anode contribution to the polarization resistance is negligible. Our analysis showed that the electrochemical reaction is limited by mass transfer control when the airflow rate is decreased to 500 ml min−1. The maximum power density is 204.6 mW cm−2 at 800 °C with H2 and air at flow rates of 800 and 2000 ml min−1, respectively. According to the AC-impedance data, the resistances of charge transfer at the electrode/electrolyte interface are 3.79 and 1.90 Ω cm2. The resistances of oxygen-reduction processes are 3.63 and 1.01 Ω cm2 at 700 and 800 °C, respectively. The results from the sensitivity analysis of the variation of contact pressure between current collectors and membrane electrode assembly (MEA) show that the influence is enhanced at the regions of the high current density.  相似文献   
924.
The present study mimics cooking meats in alcohol or distilled spirit marinades by using a 0.1 M creatinine/0.05 M sugars/0.1 M threonine ethanolic model solution, in an attempt to investigate the formation of the heterocyclic amines IQ and IQx, via Maillard reaction. The results showed that ethanol accelerated the formation of IQ and IQx, in a dose-dependent manner. In an aqueous model solution of 0.1 M creatinine/0.05 M glucose/0.1 M threonine after 8 h heating at 150 °C, the contents of IQ and IQx are 16.5 ± 2.2 and 26.2 ± 4.2 mg/kg, respectively. However, at a similar Maillard browning level in the equivalent 50% ethanolic model solution after heating at the same temperature for only 4 h, the contents of IQ and IQx significantly increase to 46.0 ± 5.5 and 69.2 ± 3.4 mg/kg, respectively.  相似文献   
925.
Tea has been found to possess widespread biological functions based on a variety of laboratory data. The effects of tea on obesity and diabetes have received increasing attention. This paper reviews the evidence for the connections among tea catechins, and obesity and diabetes. Tea catechins, especially (-)-epigallocatechin gallate (EGCG), appear to have antiobesity and antidiabetic effects. While few epidemiological and clinical studies show the health benefits of EGCG on obesity and diabetes, the mechanisms of its actions are emerging based on the various laboratory data. These mechanisms may be related to certain pathways, such as through the modulations of energy balance, endocrine systems, food intake, lipid and carbohydrate metabolism, the redox status, and activities of different types of cells (i. e., fat, liver, muscle, and beta-pancreatic cells). Because the EGCG receptor, the so-called 67-kDa laminin receptor (LR), has been discovered with colocalization of other types of LR and cytoskeleton in both cancer cells and normal cells, this may explain that EGCG possesses numerous actions. The mechanistic results of this review may possibly be utilized in the treatment of obesity, diabetes, and other related diseases using tea- and EGCG-based folk medicines.  相似文献   
926.
The use of root-end filling materials designed to stimulate hard and soft tissue repair in periradicular tissues is highly recommended. The materials should demonstrate good cell and tissue compatibility. The aim of the present study was to compare in vitro biocompatibility and in vivo tissue reaction with calcium hydroxide-based, eugenol-based and mineral trioxide aggregate root-end filling materials. The human osteosarcoma cell line was treated with immersed root end filling materials. The test materials were implanted in rats and the results observed at 6 and 8 weeks. In vitro, the highest survival rate was demonstrated for the mineral trioxide aggregate (p<0.05). In vivo, a radiopaque ring was evident in the calcium hydroxide implants on the eight-week radiograph. Histopathology revealed eugenol-based material with the inflammatory cells around the implant, with fibrous connective tissue forming around the calcium hydroxide-based analog. The mineral trioxide aggregate appears to be well tolerated by the tissue.  相似文献   
927.
Proton-exchanged 36 degrees Y-X LiTaO3 waveguides for surface acoustic wave   总被引:1,自引:0,他引:1  
A nontoxic proton source, octanoic acid, was adopted to fabricate proton-exchanged (PE) waveguides in 36 degrees Y-X lithium tantalate (LiTaO3) substrates. The PE ability of octanoic acid on LiTaO3, the penetration depth, was investigated by secondary-ion mass spectrometry (SIMS). The penetration depth of hydrogen ion exhibited an obviously step-like profile, which will be excellent for waveguide application. The relationship between waveguide depth (d) and exchanging time (t) was represented by d = 0.0653 X square root of t at T = 200 degrees C. To deserve to be mentioned, the octanoic acid has a slight dissociation coefficient and low activation energy, thus the accurate waveguide depth control can be obtained. For the application of acoustic wave guided acousto-optic devices, the leaky surface acoustic wave (LSAW) properties of PE 36 degrees Y-X LiTaO3 waveguides were investigated. The phase velocity slightly decreased with the increase of kd, where k was wavenumber. An indispensable parameter of acoustic wave device, the temperature coefficient of frequency (TCF), calculated from the frequency change of the output of LSAW delay line showed an increase with increased kd.  相似文献   
928.
Self-assembly of regular protein surfaces around nanoparticle templates provides a new class of hybrid biomaterials with potential applications in medical imaging and in bioanalytical sensing. We report here the first example of efficiently self-assembled virus-like particles (VLPs) having a brome mosaic virus protein coat and a functionalized gold core. The present study indicates that functionalized gold particles can initiate VLP assembly by mimicking the electrostatic behavior of the nucleic acid component of the native virus. These VLP constructs are symmetric, with the protein stoichiometry and packaging properties indicating similarity to the icosahedral packing of the capsid. Moreover, a pH-induced swelling transition of the VLPs is observed, in direct analogy to the native virus.  相似文献   
929.
Alkanolamines are widely used in the purification of the sourgas sweetening process. During the sour gas absorption process, CO_2 significantly degrades the amine solvent and creates enormous problems for plant operation. In this work, CO_2 induced degradation of aqueous diethanolamine(DEA) solution was conducted in a 1.25 L jacketed glass reactor that functioned as an absorber and stripper at atmospheric conditions. Pure CO_2 was bubbled through the reactor until the solution became saturated. In this study, the concentrations of DEA used were in the range of concentrations between 2 mol·L~(-1) and 4 mol·L~(-1). In the degradation experiment, six generic cycles were conducted for each run. Each cycle was configured with the absorption and desorption of carbon dioxide at 55 ℃ and 100 ℃, respectively. Samples were collected after a predetermined experimental time and analyzed by ion chromatography(IC) to identify unknown ionic degradation products(DGPs). In the IC analysis, three different columns were used for anion, cation and ion exclusion systems, which are Metrosep A Supp 5150/4.0, Metrosep C Supp 4 150/4.0 and Metrosep Organic Acids, respectively. The major identified DGPs of D01 DEA2 M, D02 DEA3 M, and D03 DEA4 M are nitrite, acetate and ammonium. Phosphate product was found in the degraded amine samples which might be due to the contamination of water or chromatographic system.  相似文献   
930.
In this paper, a comprehensive study of the reliability mechanisms of high-performance low-temperature polycrystalline-Si thin-film transistor (LTPS-TFT) with gate dielectric is reported for the first time. Various bias- and temperature-stress conditions, which correspond to positive-bias stress (PBS), positive-bias temperature instability (PBTI), negative-bias stress (NBS), negative-bias temperature instability (NBTI), and hot-carrier stress, are used to differentiate the distribution and mechanism of trap density states. The generation of deep-trap states of the effective interfacial layer (IL), tail-trap states of poly-Si grain boundaries, and electron trapping of the gate dielectric is observed for the PBS and PBTI of the LTPS-TFT. In addition, both the deep- and tail-trap states of the effective IL are generated under NBS and NBTI of the LTPS-TFT.  相似文献   
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