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许子智 《电力标准化与技术经济》2007,16(2):27-27,38
国家电网公司作为电网建设和运营的主体,是关系国家能源安全和经济命脉的国有重要骨干企业.建设坚强可靠的电网,满足经济社会发展的电力需求,确保国有企业健康可持续发展,为建设和谐社会打下坚实的物质基础是国网公司义不容辞的义务与责任. 相似文献
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Colorectal hydrosonography in diagnosis of tumorous and inflammatory diseases of the large intestine
PURPOSE: Evaluation as to whether diagnosis of large bowel disease and TNM staging of colorectal carcinoma are possible by colorectal hydrosonography (HUS). METHOD: 52 patients with suspected neoplastic or inflammatory large bowel disease, underwent HUS. Before performing abdominal ultrasound, the colon was filled with fluid. Morphological alterations of the bowel wall were judged benign or malignant. Colorectal carcinomas were classified according to the TNM system. RESULTS: Laparotomy was performed in 46 of 52 patients. Correlation with surgery and histopathology showed that 77% of morphologic alterations of the colonic wall were detected by HUS. While benign lesions of the colonic wall occasionally mimicked malignant disease, colonic carcinomas were reliably diagnosed by HUS, because destruction and invasion of the bowel wall was visible. Carcinomas of the lower part of the rectum, however, were missed in most cases. Accuracy to determine the infiltration depth of colorectal carcinomas was 89%, but hydrosonographic N-staging was unreliable. Inflammatory disease of the large bowel as well as changes complicating the inflammatory bowel disease were accurately diagnosed by HUS. CONCLUSION: In selected patients, colorectal HUS is suited for diagnosis and staging of colonic tumours. It also helps to evaluate inflammatory bowel disease, because small and large bowel can be reliably distinguished from each other and the degree of stenosis of inflamed colonic segments becomes visible. Furthermore, HUS increases the visibility of fistulas. 相似文献
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We took advantage of the partial protection exerted by suitable dosages of nicotinamide against the beta-cytotoxic effect of streptozotocin (STZ) to create a new experimental diabetic syndrome in adult rats that appears closer to NIDDM than other available animal models with regard to insulin responsiveness to glucose and sulfonylureas. Among the various dosages of nicotinamide tested in 3-month-old Wistar rats (100-350 mg/kg body wt), the dosage of 230 mg/kg, given intraperitoneally 15 min before STZ administration (65 mg/kg i.v.) yielded a maximum of animals with moderate and stable nonfasting hyperglycemia (155 +/- 3 vs. 121 +/- 3 mg/dl in controls; P < 0.05) and 40% preservation of pancreatic insulin stores. We also evaluated beta-cell function both in vitro and in vivo 4-9 weeks after inducing diabetes. In the isolated perfused pancreas, insulin response to glucose elevation (5-11 mmol/l) was clearly present, although significantly reduced with respect to controls (P < 0.01). Moreover, the insulin response to tolbutamide (0.19 mmol/l) was similar to that observed in normal pancreases. Perfused pancreases from diabetic animals also exhibited a striking hypersensitivity to arginine infusion (7 mmol/l). In rats administered STZ plus nicotinamide, intravenous glucose tolerance tests revealed clear abnormalities in glucose tolerance and insulin responsiveness, which were interestingly reversed by tolbutamide administration (40 mg/kg i.v.). In conclusion, this novel NIDDM syndrome with reduced pancreatic insulin stores, which is similar to human NIDDM in that it has a significant response to glucose (although abnormal in kinetics) and preserved sensitivity to tolbutamide, may provide a particularly advantageous tool for pharmacological investigations of new insulinotropic agents. 相似文献
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HJ Hansmann R Kosa M Düx M Brado T Goeser T Roeren W Stremmel GW Kauffmann 《Canadian Metallurgical Quarterly》1997,167(2):132-138
OBJECTIVE: This study examined the effects of an interpersonal stressor on subsequent calorie intake in females with (N = 20) and without (N = 20) significant bulimic symptomatology. METHOD: Subjects participated in two laboratory sessions that differed according to experimental condition (stress versus no stress), completed self-report measures of mood and anxiety before and after the experimental task, and were provided with an array of snack foods after each session. RESULTS: Counter to the hypothesis, women with bulimic symptoms did not differentially increase their intake when exposed to stress. However, results for the intake of each macronutrient indicated that both bulimic and control women increased their consumption of carbohydrates following the stressor. Thus, stress was related to increased carbohydrate consumption by all subjects but did not differentially affect the consumption of women with bulimic symptoms. CONCLUSIONS: It may be that women with bulimic symptoms are not differentially vulnerable to eating in response to stress or that current laboratory paradigms are unable to detect differences in eating following a stressor. 相似文献
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A Düx 《Canadian Metallurgical Quarterly》1976,29(6):263-277
The diagnostic spectrum for venography of the trunk is broad. During the traditional superior and inferior cavography, which should be used for clinical bone marrow functional blockage in connection with a confirmed tumor or for thrombosis, the combined retroperitoneal venography and cavography which we developed for clinical use as well as direct azygography provide valuable supplementary information which can be significant especially for preoperative questions. In the case of carcinoma of the esophagus or stomach, the question whether or not the tumor can be surgically removed or whether the tumor is already inoperable may be answered before surgery. In addition, direct azygography is suitable as a method to seach for lymph nodes metastases in carcinomas of the lung, stomach, kidney, adrenals and pancreas which cannot be ascertained via mediastinalscopy, and for systemic diseases. In addition to the prognostic evaluation of the tumor and the additional preoperative evaluation of neighboring tumors, various bone diseases of the lumbar vertebrae, e.g., inflammatory, tumerous and traumatic changes in the spine, may be localized on the retroperitoneal venogram and cavogram. They can also be used successfully to seach for metastases or in the case of a dislocation of an intervertebral disk. The execution of the various methods is relatively simple and they may be performed on a patient capable of surgery. 相似文献