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81.
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青岛市管道燃气公司在大尧罐站对低压16.5万m3干式气柜采用城市燃气直接置换,经合理确定置换范围,标准及过程,成功地进行了低压16.5万m3干式气相及其管道采用城市煤气直接置换的操作。 相似文献
84.
We performed simultaneous fasting and fed antroduodenal manometry and EGG in 25 children with functional bowel disorders. Three patients (12%) had an uninterpretable EGG. The manometric studies showed severe neuropathy in six patients; milder neuropathic changes in five patients; postprandial hypomotility in one patient; myopathy in four patients, and normal motility in the remaining six patients. The percentage of tachygastria time (frequency > 3.5 cycles/min) was higher in the patiens with mild (44.1 +/- 15.8%) and severe (48 +/- 19.1%) neuropathy than in the patients with myopathy (20 +/- 16.2%, P < 0.05) or with normal motility (23 +/- 13.3%, P < 0.05). There was a considerable overlap in the percentage of tachygastria and total arrhythmia time among the different study groups. The ratio of post- to preprandial power was significantly higher (2.5 +/- 0.07) in children with normal motility than in the other patients groups. Every child with total arrhythmia time < 35% and a ratio of post- to preprandial power > 2.4 had normal manometry. In summary, EGG differentiated groups of children with normal manometry from others with neuropathic or myopathic changes, but in a minority of patients the study was not interpretable and there was overlap in EGG results between children with normal and abnormal manometry. 相似文献
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86.
Recent studies have shown that, in Chinese hamster ovary cells transfected with D2-receptor cDNA, CHO(D2) cells, D2 agonists are potent in enhancing the release of [3H]arachidonic acid (AA) induced by stimulation of constitutive purinergic receptors or by application of Ca2+ ionophores. This facilitatory action is further amplified by the concomitant activation of D1 receptors, which per se have no effect on evoked [3H]AA release. Here, we review a series of experiments aimed at examining the molecular mechanism of this synergistic interaction. The results show that, in CHO(D2) cells: (a) application of 8-Br-cAMP or stimulation of constitutive prostaglandin (PG)E2 receptors augment the AA response produced by D2 agonists; (b) in CHO(D2) cells transfected with human beta 2-receptor cDNA, the beta-agonist, isoproterenol, produces a similar effect; (c) the potentiation of [3H]AA release produced by PGE2 and 8-Br-cAMP is prevented by overexpressing either a protein inhibitor of cAMP-dependent protein kinase (PKA) or a mutated form of pKA regulatory subunit incapable of binding cAMP; (d) mock-synergism is obtained in CHO(D2) cells overexpressing the catalytic subunit of PKA; (e) PGE2 is a major AA metabolite in stimulated CHO(D2) cells and its formation may contribute to the effect of D2 agonists on AA release. The results indicate that cAMP-induced activation of PKA represents a likely molecular basis for D1/D2 receptor synergism on AA release. They also suggest that additional membrane receptors, colocalized with D2 and positively linked to adenylyl cyclase, may exert a similar action. Furthermore, stimulation of PGE2 receptors by endogenously produced prostaglandin may participate in AA signaling at the D2 receptor, by providing a paracrine positive feedback loop. 相似文献
87.
L De Petrocellis P Orlando M Gavagnin M Ventriglia G Cimino V Di Marzo 《Canadian Metallurgical Quarterly》1996,52(9):874-877
Five novel 1,2-sn-diacylglycerols with diterpenoid acyl moieties in the sn-1 position were isolated and characterized, together with the corresponding 1,3-sn-diacylglycerols, from three species of dorid nudibranchs molluscs. Their potent activity as morphogens in vivo in the Hydra tentacle regeneration assay and their parallel activity as activators of rat brain protein kinase C (PKC) in vitro are reported here. Our findings promote the use of these compounds as useful molecular probes for both in vivo and in vitro studies on the participation of PKC in cell development. 相似文献
88.
Sun Qing-Ping Guo Tian-Fu Li Xue-Jun Zhang Xing 《International Journal of Fracture》1996,78(3-4):315-330
Numerical study by the finite element method (FEM) is performed to investigate the effect of dual-scale microstructure on the toughness of laminar zirconia composite. The computation is based on the micromechanics constitutive model of polycrystal transformation plasticity developed by Sun et al. [10] where both transformation induced shear and softening effects during autocatalytic transformation are taken into account. The numerical simulation presented in this paper successfully reproduced the experimentally observed two effects of the dual-scale microstructure on the toughness of laminar zirconia composite, i.e., the truncation of the elongated transformation frontal zone that forms in single phase Ce-ZrO2 and the propagation of the transformation zone along the layers normal to the crack plane. Quantitative analysis on the role of microstructure in transformation toughening of laminar zirconia composite is first carried out in the present work which will provide a starting point for the microstructural design of this novel advanced composite in the future.Presented at the Far East Fracture Group (FEFG) International Symposium on Fracture and Strength of Solids. 4–7 July 1994 in Xi'an, China. 相似文献
89.
90.
Giuseppe Gradenigo (1859-1926) was an important figure in the development of Otology. Within this paper the authors consider his background and his particular contributions to the development of various aspects of audiology. 相似文献