充气钻井井筒压力分布规律研究

以多相流理论和欠平衡钻井基本原理为基础,研究了充气钻井的压力控制问题,建立了适合充气欠平衡钻井的物理模型,同时给出了井筒压力计算的多相流理论模型和数值求解方法.结合现场资料,计算了充气钻井时井筒压力随回压和注气量的变化情况,并对其变化情况进行了解释.得出的结论为进行合理的欠压值设计提供了理论依据,对指导和实施欠平衡钻井作业和研究具有一定的理论参考.     

双栈终端在IPv4-IPv6过渡期访问WAP业务的技术实现

目前WAP业务访问的主机均为IPv4主机,随着3G时代的到来以及IPv4地址的枯竭,将业务引入到IPv6网络是发展趋势,文章将WAP业务从终端到最终访问的业务主机过程进行了贯穿性的描述,重点说明了该业务由IPv4网络向IPv6网络过渡阶段的一些技术实现。     

真丝绸小浴比染色技术探讨及工艺实践

传统的真丝绸染色通常在绳状染色机、平幅卷染机等设备上完成,染色浴比1∶4～1∶50甚至更大。采用液雾喷染小浴比染色,浴比仅为1∶2～1∶3。与传统染色机相比,小浴比染色的用水量大为减少,文章对由此引起的染料溶解、助剂选用以及工艺实施等方面的问题进行了研究探讨,提出相应的解决措施,并在工厂真丝绸染色生产中进行实际应用,获得了良好的应用效果。     

Creation and control of high-dimensional multi-partite classically entangled light

Vector beams, non-separable in spatial mode and polarisation, have emerged as enabling tools in many diverse applications, from communication to imaging. This a...     

多稳态电磁俘能系统的非线性动力学实验研究

为克服共振式俘能器工作频带窄和压电式俘能器输出电流低等问题,设计了多稳态电磁式振动俘能系统.建立了系统的分数阶阻尼模型,通过实验揭示了多稳态电磁俘能系统的动态分岔、势能阱逃逸、高能态轨道和混沌运动等非线性行为.结果表明:采用庞加莱截面频闪采样算法和分岔图可有效刻画系统的非线性振动特性;利用多稳态电磁式俘能系统的非线性振...     

电容器故障监测系统的应用研究

基于近年并联电容器装置频繁出现故障的现象和特点,研制出一套电容器故障监测系统,分别提取并联电容器装置的电流和电压实时信号,利用Labview虚拟仪器程序进行软件开发实现在线监测,对获取的电流电压信号进行谐波、合闸涌流、暂态过电压等方面进行分析和研究,并应用于现场测量,给出了一起电容器内部击穿故障的监测实例。     

高性能计算机电源系统的设计与实现

从系统级、机柜级、板级三方面详细介绍了某高性能计算机电源系统的实现方案。重点介绍了计算板的电源和控制电路的设计方法,并对电源系统的稳定性进行了分析,提出了解决方法,最后给出了系统运行时的电源实测波形。运行结果表明,该系统具有供电质量高,可靠性高,易于维护,能进行故障诊断等优点。     

The Regulatory Role of H19/miR-181a/ATG5 Signaling in Perinatal Nicotine Exposure-Induced Development of Neonatal Brain Hypoxic-Ischemic Sensitive Phenotype

Nicotine exposure either from maternal cigarette smoking or e-cigarette vaping is one of the most common risk factors for neurodevelopmental disease in offspring. Previous studies revealed that perinatal nicotine exposure programs a sensitive phenotype to neonatal hypoxic-ischemic encephalopathy (HIE) in postnatal life, yet the underlying mechanisms remain undetermined. The goal of the present study was to determine the regulatory role of H19/miR-181a/ATG5 signaling in perinatal nicotine exposure-induced development of neonatal brain hypoxic-ischemic sensitive phenotype. Nicotine was administered to pregnant rats via subcutaneous osmotic minipumps. All experiments were conducted in offspring pups at postnatal day 9 (P9). Perinatal nicotine exposure significantly enhanced expression of miR-181a but attenuated autophagy-related protein 5 (ATG5) mRNA and protein levels in neonatal brains. Of interest, miR-181a mimicking administration in the absence of nicotine exposure also produced dose-dependent increased hypoxia/ischemia (H/I)-induced brain injury associated with a decreased ATG5 expression, closely resembling perinatal nicotine exposure-mediated effects. Locked nucleic acid (LNA)-miR-181a antisense reversed perinatal nicotine-mediated increase in H/I-induced brain injury and normalized aberrant ATG5 expression. In addition, nicotine exposure attenuated a long non-coding RNA (lncRNA) H19 expression level. Knockdown of H19 via siRNA increased the miR-181a level and enhanced H/I-induced neonatal brain injury. In conclusion, the present findings provide a novel mechanism that aberrant alteration of the H19/miR-181a/AGT5 axis plays a vital role in perinatal nicotine exposure-mediated ischemia-sensitive phenotype in offspring and suggests promising molecular targets for intervention and rescuing nicotine-induced adverse programming effects in offspring.     

上海历史文化风貌区的分类比较与保护规划的应对

2003年,上海市划定了中心城12个历史文化风貌区,它融合了上海城市发展过程中各个时代的鲜明风格,体现了近代上海在社会经济、文化、生活各方面的成就和发展轨迹.由于上海这样的大都市的历史风貌复杂、多样,每个风貌区所面临的问题也不尽相同,因此保护规划在统一的规划框架下,必须有不同的变化和侧重.分类比较的目的就是为了进一步归纳总结,完善保护规划体系,使风貌区保护规划编制方法更加易于推广.     

中空海胆状结构的碳包覆Fe2O3用作锂离子电池的高性能负极材料

Fe2O3由于成本低廉,储量丰富和理论比容量高(1007 mA hg^-1)等特点,在锂离子电池负极材料的应用中极具发展前景.然而一些问题仍然存在,如:充放电过程中比容量的迅速衰减,不可逆的体积膨胀以及较短的循环寿命等.这些问题严重制约了Fe2O3在锂离子电池中的实际应用.为了突破这些局限,本文以金属-有机骨架(MOF...