磷酸化蛋白质分析

蛋白质的磷酸化过程是人体内翻译后修饰的重要一步,非正常的磷酸化会导致人体产生各种疾病.近年来,通过分析化学的手段研究磷酸化的过程取得了很大的进展.该文就蛋白激酶分析、磷酸化多肽的富集方面的国内外的研究进展进行了综述.     

Efficient edit propagation using hierarchical data structure

This paper presents a novel unified hierarchical structure for scalable edit propagation. Our method is based on the key observation that in edit propagation, appearance varies very smoothly in those regions where the appearance is different from the user-specified pixels. Uniformly sampling in these regions leads to redundant computation. We propose to use a quadtree-based adaptive subdivision method such that more samples are selected in similar regions and less in those that are different from the user-specified regions. As a result, both the computation and the memory requirement are significantly reduced. In edit propagation, an edge-preserving propagation function is first built, and the full solution for all the pixels can be computed by interpolating from the solution obtained from the adaptively subdivided domain. Furthermore, our approach can be easily extended to accelerate video edit propagation using an adaptive octree structure. In order to improve user interaction, we introduce several new Gaussian Mixture Model (GMM) brushes to find pixels that are similar to the user-specified regions. Compared with previous methods, our approach requires significantly less time and memory, while achieving visually same results. Experimental results demonstrate the efficiency and effectiveness of our approach on high-resolution photographs and videos.     

Design of a novel monopulse antenna system using the time‐modulated antenna arrays

A novel monopulse antenna for a tracking radar system is proposed using the time modulated antenna array technique. The time modulation technique applied in the antenna arrays overcomes the usual need for compromise between sum and difference beams and avoids the need for implementation of two separate feed networks. The time modulated antenna array also relaxes the error tolerance of the tracking accuracy from the amplitude and phase errors, due to the new design freedom of “time” which can be controlled precisely and quickly. Moreover, the position of the target can be recovered by two reflected echoes from one previously transmitted pulse, thus the tracking errors resulting from the excitation errors and receiver noise in conventional antenna arrays can be greatly alleviated. Numerical results show that with the aid of time modulation technique, one sum beam and two difference beams can be simultaneously obtained either for the boresight or off‐boresight target tracking. © 2010 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2010.     

Efficient analysis of wireless communication antennas using an accurate [Z] matrix interpolation technique

An accurate impedance matrix interpolation technique based on the surface integral equation (SIE) is presented for the analysis of wireless communication antennas over wide frequency bands. The first‐order derivative of the impedance matrix at the internal frequency is considered in the cubic polynomial‐based interpolation scheme, thus the novel impedance matrix interpolation scheme will provide high accuracy and high efficiency over a frequency band. To demonstrate the efficiency and accuracy of the proposed method, numerical results for planar inverted F antennas (PIFA) and a wideband E‐shaped patch antenna are presented. Good agreement among the interpolation results, exact MoM solutions, finite element method (FEM) solutions, and measured data is observed over the bandwidth. Besides, dimensions of the feeding probe are also studied to investigate their effect on the input impedance and radiation patterns. © 2010 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2010.     

Tuning of multi-loop PI controllers based on gain and phase margin specifications

In this paper, a single-iteration strategy is proposed for the design of a multi-loop PI controller to achieve the desired gain and phase margins for two-input and two-output (TITO) processes. To handle loop interactions, a TITO system is converted into two equivalent single loops with uncertainties drawn from interactions. The maximum uncertainty is estimated for the initial controller design in one loop and single-input and single-output (SISO) controller design is applied. This controller is substituted to other equivalent loop for design, and finally, the first loop controller is refined on knowledge of other loop controller. For SISO controller tuning, a new method is presented to determine the achievable gain and phase margins as well as the relevant controller parameters. Examples are given for illustration and comparison.     

一种基于接口匹配的组合Web服务描述语言

从基于WSDL的服务接口描述语言入手,分析了Web服务组合的类型和消息依赖关系.将服务组合分为顺序组合、替换组合、混合式组合三种类型;结合这些类型,将组合服务中的消息依赖定义为消息映射依赖、消息合成依赖和消息分解依赖三种关系.在此基础上,提出了一种轻量级的组合服务描述语言(CWSDL).     

Estimating clear-sky land surface longwave upwelling radiation from MODIS data using a hybrid method

Surface longwave upwelling radiation (LWUP) is one of the four components for calculating the earth’s surface radiation budget. Under the general framework of the hybrid method, we developed linear models for estimating the global 1-km instantaneous clear-sky LWUP from the top-of-atmosphere (TOA) radiance of the Moderate Resolution Imaging Spectroradiometer (MODIS) thermal infrared channels 29, 31, and 32. Extensive radiative transfer simulations were conducted to produce a large number of representative samples, from which the linear model was derived. The derived hybrid model was first evaluated using ground measurements collected at 15 sites from two networks (SURFRAD and ASRCOP). According to the validation results, the average bias and root mean square error (RMSE) of ?0.55 and 15.76 W m^?2, respectively, were obtained by averaging the mean bias and RMSE for the two networks. Compared to a hybrid method developed by a previous study and the temperature-emissivity method, our linear model had a superior performance.     

The simulation and visual test contact process of a MEMS inertial switch with flexible electrodes

A MEMS inertial switch with flexible electrodes to contact-enhanced is designed and fabricated. ANSYS software is used to simulate the displacement of the mass, deformation of the flexible electrode and contact time of the switch. A high-speed video measurement has been used to visualize the switch contact process instead of electrical measurement for a deeper understanding of the dynamic contact process, and these images are used to visually validate simulation results. Comparisons between the simulation and image results are discussed. The image results are seen to be in good agreement with the dynamics simulation results.     

COS和H_2S毒化F-T合成催化剂热力学分析

利用热力学基础数据和相关软件对F-T合成催化剂COS和H_2S中毒的热力学进行了计算。在热力学上,Ru、Fe、Co的COS中毒在F-T合成反应可以发生的条件下均是自发过程。F-T合成反应体系中10~(-9)级的COS即可使Ru基催化剂中的金属Ru生成RuS_2而中毒。Fe和Co毒化后生成的硫化物种类较多,对这些反应的热力学计算结果表明,对于不同的反应,其平衡常数的差异很大,对应中毒反应发生时,所需的COS和H_2S的浓度也不同,对COS的要求更为严格。由于Fe基F-T合成催化剂活性相的复杂性,利用对催化剂相关性质的修饰开发具有一定抗硫性的铁基F-T合成催化剂是可行的;对于Co催化剂,利用F-T合成的反应特点和催化剂改性开发具有一定抗硫性催化剂是可能的。