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11.
12.
Priyadarshi Chakraborty Yiming Tang Tomoya Yamamoto Yifei Yao Tom Guterman Shai Zilberzwige-Tal Nofar Adadi Wei Ji Tal Dvir Ayyalusamy Ramamoorthy Guanghong Wei Ehud Gazit 《Advanced materials (Deerfield Beach, Fla.)》2020,32(9):1906043
Self-assembled peptide hydrogels represent the realization of peptide nanotechnology into biomedical products. There is a continuous quest to identify the simplest building blocks and optimize their critical gelation concentration (CGC). Herein, a minimalistic, de novo dipeptide, Fmoc-Lys(Fmoc)-Asp, as an hydrogelator with the lowest CGC ever reported, almost fourfold lower as compared to that of a large hexadecapeptide previously described, is reported. The dipeptide self-assembles through an unusual and unprecedented two-step process as elucidated by solid-state NMR and molecular dynamics simulation. The hydrogel is cytocompatible and supports 2D/3D cell growth. Conductive composite gels composed of Fmoc-Lys(Fmoc)-Asp and a conductive polymer exhibit excellent DNA binding. Fmoc-Lys(Fmoc)-Asp exhibits the lowest CGC and highest mechanical properties when compared to a library of dipeptide analogues, thus validating the uniqueness of the molecular design which confers useful properties for various potential applications. 相似文献
13.
Energy transfer from photo-excited electrons in a metal thin film to the dielectric substrate is important for understanding the ultrafast heat transfer process across the two materials. Substantial research has been conducted to investigate heat transfer in a metal-dielectric structure. In this work, a two-temperature model in metal was used to analyze the interface electron and dielectric substrate coupling. An improved temperature and wavelength-dependent Drude–Lorentz model was implemented to interpret the signals obtained in optical measurements. Ultrafast pump-and-probe measurements on Au-Si samples were carried out, where the probe photon energy was chosen to be close to the interband transition threshold of gold to minimize the influence of non-equilibrium electrons on the optical response and maximize the thermal modulation to the optical reflectance. Electron-substrate interface thermal conductance at different pump laser fluences was obtained, and was found to increase with the interface temperature. 相似文献
14.
结合实例详解了华中数控系统复合循环指令G71在实际编程与加工中的应用。此指令的应用,解决了在加工轴类零件过程中运用传统的加工方法难以满足形状复杂、精度高等要求的问题,从而提高了工作效率。 相似文献
15.
Baizhan Li Chenqiu Du Hong Liu Wei Yu Jie Zheng Meilan Tan Zhenxing Jin Wenjie Li Jing Wu Lu Chen Runming Yao 《Indoor air》2019,29(2):308-319
The extensive research interests in environmental temperature can be linked to human productivity / performance as well as comfort and health; while the mechanisms of physiological indices responding to temperature variations remain incompletely understood. This study adopted a physiological sensory nerve conduction velocity (SCV) as a temperature‐sensitive biomarker to explore the thermoregulatory mechanisms of human responding to annual temperatures. The measurements of subjects’ SCV (over 600 samples) were conducted in a naturally ventilated environment over all four seasons. The results showed a positive correlation between SCV and annual temperatures and a Boltzmann model was adopted to depict the S‐shaped trend of SCV with operative temperatures from 5°C to 40°C. The SCV increased linearly with operative temperatures from 14.28°C to 20.5°C and responded sensitively for 10.19°C‐24.59°C, while tended to be stable beyond that. The subjects’ thermal sensations were linearly related to SCV, elaborating the relation between human physiological regulations and subjective thermal perception variations. The findings reveal the body SCV regulatory characteristics in different operative temperature intervals, thereby giving a deeper insight into human autonomic thermoregulation and benefiting for built environment designs, meantime minimizing the temperature‐invoked risks to human health and well‐being. 相似文献
16.
Yao Dajie Liu Xiaofei Wu Jian 《International Journal of Control, Automation and Systems》2020,18(9):2251-2258
International Journal of Control, Automation and Systems - In this paper, the tracking problem for a class of uncertain nonlinearly parameterized systems with input delay based the adaptive... 相似文献
17.
To minimize the mass and increase the bearing failure load of composite doublelap bolted joints, a three-step optimization strategy including feasible region reduction,
optimization model decoupling and optimization was presented. In feasible region
reduction, the dimensions of the feasible design region were reduced by selecting dominant
design variables from numerous multilevel parameters by sensitivity analyses, and the
feasible regions of variables were reduced by influence mechanism analyses. In model
decoupling, the optimization model with a large number of variables was divided into
various sub-models with fewer variables by variance analysis. In the third step, the
optimization sub-models were solved one by one using a genetic algorithm, and the
modified characteristic curve method was adopted as the failure prediction method. Based
on the proposed optimization method, optimization of a double-lap single-bolt joint was
performed using the ANSYS® code. The results show that the bearing failure load increased
by 13.5% and that the mass decreased by 8.7% compared with those of the initial design of
the joint, which validated the effectiveness of the three-step optimization strategy. 相似文献
18.
针对甲醇液相氧化羰基化法合成碳酸二甲酯(DMC)工艺,开发了新型Cu基络合催化剂(CuB rnLm)。对CuB rnLm催化剂的活性及其稳定性进行了研究。实验结果表明,采用该催化剂,甲醇转化率和DMC选择性较高;元素价态和物质结构分析表明,CuB rnLm催化剂循环使用5次后仍保持较好的稳定性。采用正交设计和中心响应曲面法设计实验,并使用S tatistica软件进行统计分析,寻求出反应的主要影响因素,并得到优化的工艺条件:反应温度100~110℃、反应压力3.0~3.5M Pa、反应时间4~6h、CuB rnLm催化剂质量浓度(以甲醇的体积计)0.15~0.20g/mL。在此工艺条件下,甲醇转化率可达23%以上,DMC的选择性为96%~98%。 相似文献
19.
推进农村通信和信息化发展的若干建议 总被引:1,自引:0,他引:1
农村地区的通信和互联网建设,是全面建设小康社会的重要基础设施之一,是一项艰巨、繁重的任务.信息产业部制定的不同时期的电信发展目标规划,具有求实性、可操作性.思前想后,各级政府的政策支持和电信运营企业尽责参与,仍是推进农村通信和农村信息化快速发展之路.然而,在电信普遍服务基金渠道、农村通信设备选用、农村信息化模式、地域目标规划等方面尚需论证落实,这是稳步实现电信小康目标的保障. 相似文献
20.
结合国内外对碳钢CO2腐蚀影响因素的研究成果,采用模糊层次分析法对影响输油管道 CO2腐蚀的因素进行定量分析,明确界定出这些因素对二氧化碳腐蚀影响的相对重要性(权重),为后续制定经济有效的管道内腐蚀防护措施提供了客观依据。 相似文献