Product modularization for life cycle engineering

Modular products consist of detachable modules, which can be manufactured, assembled, and serviced separately. Some of the modules may be reusable, recyclable or re-manufacturable upon product retirement. Thus, modular design can provide benefits to many aspects of product life cycle. This paper presents an integrated modular design methodology for life cycle engineering. The methodology consists of three phases: problem definition, interaction analysis and module formation. The methodology identifies the factors related to the design objectives, relates these factors to design components through interaction analysis, and clusters components into modules. Two case studies along with detailed analysis are provided to illustrate the methodology and the algorithms.     

荧光灯闪烁和视疲劳关系的实验研究

本研究在模拟教室、家庭阅读环境及 VDT环境三种场景下 ,测试被试在不同闪烁频率光源下进行单词查找、数字校对、光栅圈、兰道环等视觉作业的速度及正确率 ,并对他们的主观感受进行调查。结果直流荧光灯下 ,视觉功效高 ,说明降低荧光灯闪烁可减轻视觉疲劳程度     

选矿浓缩过程矿浆浓度的模糊控制

针对治金行业选矿浓缩过程的工艺特点,介绍了基于变频技术的矿浆浓度模糊控制,较好地控制了浓度指标,同时也稳定了矿浆流量并大幅度节能降耗。该设计已在宝钢、武钢等选矿厂中得到成功应用,效益显著。     

Correction strategy of fuel injection quantity during pilot-main injection for common rail system

Journal of Mechanical Science and Technology - Common rail system is a key technology of energy saving and emission reduction for modern diesel engines. Multiple injection, as one of the most...     

Carbon Metabolism of a Soilborne Mn(II)-Oxidizing Escherichia coli Isolate Implicated as a Pronounced Modulator of Bacterial Mn Oxidation

Mn(II)-oxidizing microorganisms are generally considered the primary driving forces in the biological formation of Mn oxides. However, the mechanistic elucidation of the actuation and regulation of Mn oxidation in soilborne bacteria remains elusive. Here, we performed joint multiple gene-knockout analyses and comparative morphological and physiological determinations to characterize the influence of carbon metabolism on the Mn oxide deposit amount (MnODA) and the Mn oxide formation of a soilborne bacterium, Escherichia coli MB266. Different carbon source substances exhibited significantly varied effects on the MnODA of MB266. A total of 16 carbon metabolism-related genes with significant variant expression levels under Mn supplementation conditions were knocked out in the MB266 genome accordingly, but only little effect on the MnODA of each mutant strain was accounted for. However, a simultaneous four-gene-knockout mutant (namely, MB801) showed an overall remarkable MnODA reduction and an initially delayed Mn oxide formation compared with the wild-type MB266. The assays using scanning/transmission electron microscopy verified that MB801 exhibited not only a delayed Mn-oxide aggregate processing, but also relatively smaller microspherical agglomerations, and presented flocculent deposit Mn oxides compared with normal fibrous and crystalline Mn oxides formed by MB266. Moreover, the Mn oxide aggregate formation was highly related to the intracellular ROS level. Thus, this study demonstrates that carbon metabolism acts as a pronounced modulator of MnODA in MB266, which will provide new insights into the occurrence of Mn oxidation and Mn oxide formation by soilborne bacteria in habitats where Mn(II) naturally occurs.     

脉冲电流在改善金属凝固组织中的作用

综述了脉冲电流在改善金属凝固组织方面的研究现状。从理论上归纳和分析了脉冲电流在金属凝固过程中产生作用的主要机制。     

服装材料悬垂伸长量与成衣样板修正量的研究

服装材料是成衣生产与制作的基本要素,其特性将直接影响成衣穿着的美观和舒适度,也影响成衣生产中工业样板的准确性.通过自制的模具(180°半圆模型)测量服装材料在悬垂状态下不同纱向、不同基础长度的悬垂伸长量,进行科学合理的量化分析,总结出服装材料悬垂伸长的规律.通过函数关系建立了服装材料悬垂伸长量和成衣样板修正量间的关系,为成衣样板的修正提供了科学的、可靠的依据,提高了成衣工业样板的制作效率和结构、规格的精度.     

Differential MicroRNA Expression in Porcine Endometrium Related to Spontaneous Embryo Loss during Early Pregnancy

Litter size is an important indicator to measure the production capacity of commercial pigs. Spontaneous embryo loss is an essential factor in determining sow litter size. In early pregnancy, spontaneous embryo loss in porcine is as high as 20–30% during embryo implantation. However, the specific molecular mechanism underlying spontaneous embryo loss at the end of embryo implantation remains unknown. Therefore, we comprehensively used small RNA sequencing technology, bioinformatics analysis, and molecular experiments to determine the microRNA (miRNA) expression profile in the healthy and arresting embryo implantation site of porcine endometrium on day of gestation (DG) 28. A total of 464 miRNAs were identified in arresting endometrium (AE) and healthy endometrium (HE), and 139 differentially expressed miRNAs (DEMs) were screened. We combined the mRNA sequencing dataset from the SRA database to predict the target genes of these miRNAs. A quantitative real-time PCR assay identified the expression levels of miRNAs and mRNAs. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were performed on differentially expressed target genes of DEMs, mainly enriched in epithelial development and amino acids metabolism-related pathways. We performed fluorescence in situ hybridization (FISH) and the dual-luciferase report gene assay to confirm miRNA and predicted target gene binding. miR-205 may inhibit its expression by combining 3′-untranslated regions (3′ UTR) of tubulointerstitial nephritis antigen-like 1 (TINAGL1). The resulting inhibition of angiogenesis in the maternal endometrium ultimately leads to the formation of arresting embryos during the implantation period. This study provides a reference for the effect of miRNA on the successful implantation of pig embryos in early gestation.