5GLAN在5G专网中的优化应用

在通信技术高速发展的背景下,5GLAN技术同样呈现出快速发展的趋势,该技术通过5G接入,可以提供LAN,VPN等类型的功能服务。自该技术诞生以来,就受到了各领域的广泛关注,尤其是在工业、交通等领域中,基于5GLAN等场景的应用,可以有效实现灵活组网、内外网融合、安全管理等目标,为LAN内5G终端互通、终端隔离等提供灵活的通信服务。基于此,文中阐述了5GLAN的特点及优势,并分析了其在5G专网中的优化应用要点。     

Macrophage Membrane-Coated Nanoparticles Sensitize Glioblastoma to Radiation by Suppressing Proneural–Mesenchymal Transformation in Glioma Stem Cells

Radiotherapy is identified as a crucial treatment for patients with glioblastoma, but recurrence is inevitable. The efficacy of radiotherapy is severely hampered partially due to the tumor evolution. Growing evidence suggests that proneural glioma stem cells can acquire mesenchymal features coupled with increased radioresistance. Thus, a better understanding of mechanisms underlying tumor subclonal evolution may develop new strategies. Herein, data highlighting a positive correlation between the accumulation of macrophage in the glioblastoma microenvironment after irradiation and mesenchymal transdifferentiation in glioblastoma are presented. Mechanistically, elevated production of inflammatory cytokines released by macrophages promotes mesenchymal transition in an NF-κB-dependent manner. Hence, rationally designed macrophage membrane-coated porous mesoporous silica nanoparticles (MMNs) in which therapeutic anti-NF-κB peptides are loaded for enhancing radiotherapy of glioblastoma are constructed. The combination of MMNs and fractionated irradiation results in the blockage of tumor evolution and therapy resistance in glioblastoma-bearing mice. Intriguingly, the macrophage invasion across the blood-brain barrier is inhibited competitively by MMNs, suggesting that these nanoparticles can fundamentally halt the evolution of radioresistant clones. Taken together, the biomimetic MMNs represent a promising strategy that prevents mesenchymal transition and improves therapeutic response to irradiation as well as overall survival in patients with glioblastoma.     

Comparison of gas sensing properties based on hollow and porous α-Fe<Subscript>2</Subscript>O<Subscript>3</Subscript> nanotubes

Hollow and porous α-Fe₂O₃ nanotubes were successfully synthesized by single nozzle electrospinning method followed by annealing treatment. The crystal structures and morphologies of the as-prepared materials were characterized by X-ray diffraction and scanning electron microscopy, respectively. The as-prepared materials were applied to construct gas sensor devices which gas sensing properties were further investigated. The obtained results revealed that porous α-Fe₂O₃ nanotube gas sensors exhibit a markedly enhanced gas sensing performance compared with hollow α-Fe₂O₃ nanotube gas sensors, which was about three times higher to 100 ppm acetone at 240 °C. Interestingly, hollow and porous α-Fe₂O₃ nanotube gas sensors both showed fast response–recovery time and good selectivity, but the porous ones possessed the shorter recovery time. The improved properties could be attributed to the unique morphology of porous nanotubes. Thus, further improvement of performance in metal-oxide-semiconductors materials could be realized by preparation the unique porous structures of nanotubes. Moreover, it is expected that porous metal-oxide-semiconductors nanotubes could be further design as promising candidates for gas sensing materials.     

商业诽谤犯罪中网络服务提供者行为的技术与法律分析

在本案中,刑法及其司法解释完全从商业诽谤犯罪实行行为的角度进行解释,没有重视网络信息服务提供者的行为特点,实际上导致难以根据刑法以及司法解释分析网络服务提供者在网络商业诽谤违法犯罪中的责任。在商业诽谤刑事案件中,网络服务提供者不仅有义务向侦查机关提供有关资料,而且由于其在信息监管责任缺位,必须对其设置责任追究的机制,从而推动其履行商业诽谤信息审查义务。     

求解分数阶微分系统的一种数值算法

由于分数阶微分系统具有记忆功能,在其求解过程中计算量较大.文中的目的是针对分数阶Grunwald-Letnikov(6L)定义,研究并寻求一种求解分数阶微分方程的有效数值算法.首先由分数阶GL定义得出分数阶的数值计算公式,进而从理论上分析了算法中分数阶项计算系数的特点,结合计算机数值仿真的结果,得出了远离当前时间的无穷小项一般不可忽略的结论,并设计了一种合理有效的计算方法.计算机数值仿真的结果表明,所设计的求解分数阶微分方程的算法精度高,通用性好,且易于编程实现.     

Silicon-based microelectrode arrays for stimulation and signal recording of in vitro cultured neurons

Microelectrode arrays (MEAs) for stimulation and signal recording of in vitro cultured neurons are presented.Each MEA is composed of 60 independent electrodes with 59 working ones and one reference one.These electrodes are divided into 30 pairs.Through each pair of electrodes,four independent states can be realized to define the accessing modes of neurons cultured on the surface of the electrodes.A total MEA covers an area of 10 mm×10 mm.MEAs are fabricated in a silicon-based semiconductor process.An implemented MEA is bonded on a specially designed printed-circuit-board (PCB) and surrounded by a culture chamber.An impedance measurement has been made to verify the electrical characteristics of MEAs.The surface was modified to enhance the biocompatibility.A series of PC12 cells culture experiments validates the effectiveness of the modification.An extracellular signal recording experiment with acetylcholine (Ach) as a stimulant has been carried out,and the results show the feasibility of MEAs for extracellular action potential recording.Extracellular electrical stimulation and recording experiments have been carried out too.They indicate that MEAs can be used for extracellular stimulation,recording,simultaneous stimulation and recording,and isolation of PC12 cells network cultured in vitro.     

嵌入式水电气在线遥监控系统研究

该文介绍了一个基于CNA总线的嵌入式Web监控水、电、气在线遥控监控系统的架构方案,重点阐述其监控水、电、气管理系统的设计思路,对其中涉及的关键技术进行了较为详细的叙述。     

一种安全有效的基于身份的门限签密方案

签密是一种将加密和数字签名技术结合在一起的思想,它比采用先签名后加密的方法具有更高的效率.基于双线性对技术,提出了一种新的基于身份的门限签密方案.它利用决策双线性Diffie-Hellman(DBDH)问题的困难性在随机预言模型下给出了方案的语义安全性证明,并利用计算Diffie-Hellman(CDH)问题的困难性证明了方案的不可伪造性,同时指出方案具有较高的效率.