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41.
The development of a photo‐responsive micellar system capable of triggering cell death is reported. Precursors of the micelles are synthesized by connecting a lipophilic chain to a hydrophilic polyethylene glycol via a photo‐labile nitrobenzyl group. The resulting amphiphilic units are self‐assembled in water forming 12 nm micelles that are readily internalized into cells. Upon photo‐irradiation, micelles undergo cleavage and yield a cytotoxic nitrosobenzaldehyde derivative, which significantly inhibits the proliferation of MDA‐MB‐231 cells under standard in vitro conditions.  相似文献   
42.
Space agencies are rapidly building up massive image databases. A particularity of these databases is that they are made of images with different, but known, resolutions. In this paper, we introduce a new scheme allowing us to compare and index images with different resolutions. This scheme relies on a simplified acquisition model of satellite images and uses continuous wavelet decompositions. We establish a correspondence between scales which permits us to compare wavelet decompositions of images having different resolutions. We validate the approach through several matching and classification experiments, and we show that taking the acquisition process into account yields better results than just using scaling properties of wavelet features.  相似文献   
43.
Generally, an intruder must perform several actions, organized in an intrusion scenario, to achieve his or her malicious objectives. Actions are modeled by their pre and post conditions, which are a set of logical predicates or negations of predicates. Pre conditions of an action correspond to conditions the system’s state must satisfy to perform the action. Post conditions correspond to the effects of executing the action on the system’s state. When an intruder begins his intrusion, we can deduce, from the alerts generated byidss (Intrusion Detection Systems), several possible scenarios, by correlating attacks, that lead to multiple intrusion objectives. However, with no further analysis, we are not able to decide which are the most plausible ones among the possible scenarios. We propose in this paper to define an order over the possible scenarios by weighting the correlation relations between successive attacks composing the scenarios. These weights reflect to what level executing some actions are necessary to execute some action B. We will see that to be satisfactory, the comparison operator between two scenarios must satisfy some properties.  相似文献   
44.
This paper addresses the problem of separating spectral sources which are linearly mixed with unknown proportions. The main difficulty of the problem is to ensure the full additivity (sum-to-one) of the mixing coefficients and non-negativity of sources and mixing coefficients. A Bayesian estimation approach based on Gamma priors was recently proposed to handle the non-negativity constraints in a linear mixture model. However, incorporating the full additivity constraint requires further developments. This paper studies a new hierarchical Bayesian model appropriate to the non-negativity and sum-to-one constraints associated to the sources and the mixing coefficients of linear mixtures. The estimation of the unknown parameters of this model is performed using samples obtained with an appropriate Gibbs algorithm. The performance of the proposed algorithm is evaluated through simulation results conducted on synthetic mixture data. The proposed approach is also applied to the processing of multicomponent chemical mixtures resulting from Raman spectroscopy.  相似文献   
45.
The performance of signal-processing algorithms implemented in hardware depends on the efficiency of datapath, memory speed and address computation. Pattern of data access in signal-processing applications is complex and it is desirable to execute the innermost loop of a kernel in a single-clock cycle. This necessitates the generation of typically three addresses per clock: two addresses for data sample/coefficient and one for the storage of processed data. Most of the Reconfigurable Processors, designed for multimedia, focus on mapping the multimedia applications written in a high-level language directly on to the reconfigurable fabric, implying the use of same datapath resources for kernel processing and address generation. This results in inconsistent and non-optimal use of finite datapath resources. Presence of a set of dedicated, efficient Address Generator Units (AGUs) helps in better utilisation of the datapath elements by using them only for kernel operations; and will certainly enhance the performance. This article focuses on the design and application-specific integrated circuit implementation of address generators for complex addressing modes required by multimedia signal-processing kernels. A novel algorithm and hardware for AGU is developed for accessing data and coefficients in a bit-reversed order for fast Fourier transform kernel spanning over log?2 N stages, AGUs for zig-zag-ordered data access for entropy coding after Discrete Cosine Transform (DCT), convolution kernels with stored/streaming data, accessing data for motion estimation using the block-matching technique and other conventional addressing modes. When mapped to hardware, they scale linearly in gate complexity with increase in the size.  相似文献   
46.
In this paper, we suggest that the Montreal School (TMS) tradition of organizational communication offers a fruitful analytical framework that allows us to better take into account the way people practically deal with plurilingual situations as they go on with their daily activities and contribute to shaping their organizations. We identify six core features of TMS and show their analytical power in studying plurilingual interactions. TMS, we argue, is conceptually well equipped to reveal the ways in which multiple tongues are dealt with in everyday organizational settings and to uncover the constitutive nature of tongue‐in‐use.  相似文献   
47.
Mechanics of Time-Dependent Materials - May it be for environmental or economic reasons, mass reduction has become one of the main goals in mechanics. The short fiber thermoplastics composite is an...  相似文献   
48.
Abstract

The paper describes the possibility of using the speckle pattern decorrelation for determination of small deformation tensor components of an elementary object surface area in an optical image field. The relationship between the small-deformation tensor and the speckle field displacement is analysed in detail. The studied problem is presented from the approximation viewpoint of both wave and geometrical optics.  相似文献   
49.
Human observers use the information offered by various visual cues when evaluating the glossiness of a surface. Several studies have demonstrated the effect of each single cue to glossiness, but little has been reported on how multiple cues are integrated for the perception of surface gloss. This paper reports on a psychophysical study with real stimuli that are different regarding multiple visual gloss criteria. Four samples were presented to 15 observers under different conditions of illumination in a light booth, resulting in a series of 16 stimuli. Through pairwise comparisons, an overall gloss scale was derived, from which it could be concluded that both differences in the distinctness of the reflected image and differences in luminance affect gloss perception. However, an investigation of the observers' strategy to evaluate gloss indicated a dichotomy among observers. One group of observers used the distinctness-of-image as a principal cue to glossiness, while the second group evaluated gloss primarily from differences in luminance of both the specular highlight and the diffuse background. It could therefore be questioned whether surface gloss can be characterized with one single quantity, or that a set of quantities is necessary to describe the gloss differences between objects.  相似文献   
50.
Levels of eight dietary elements were assessed by ICP-AES in virgin edible and beauty argan oil samples prepared from four remote locations of the argan forest, and over a three-year period. The data showed sufficiently little variability to assess that all argan oil samples present, in terms of dietary elements, a similar composition, independently from the tree location within the argan forest. Therefore, adulteration detection by trace element analysis in edible and beauty argan oil is a method that can be generalised.  相似文献   
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