Preparation of hydroxyapatite-containing titania coating on titanium substrate by micro-arc oxidation

Hydroxyapatite-containing titania coatings on titanium substrates were formed by micro-arc oxidation (MAO) in electrolyte containing calcium acetate monohydrate (CH₃COO)₂Ca·H₂O) and sodium phosphate monobasic dihydrate (NaH₂PO₄·2H₂O) using a pulse power supply. Scanning electron microscopy (SEM) with Energy dispersive X-ray spectrometer (EDX) and X-ray diffraction (XRD) were employed to characterize the microstructure, elemental composition and phase components of the coatings. The coatings were rough and porous, without apparent interface to the titanium substrates. All the oxidized coatings contained Ca and P as well as Ti and O, and the porous coatings were made up of anatase, rutile and hydroxyapatite. Such MAO films are expected to have significant applications as artificial bone joints and dental implants.     

舰船电力系统暂态稳定性仿真分析

通过分析舰船电力系统暂态稳定性的特点,并结合陆地电力系统暂态稳定性分析的理论,提出了适用于舰船电力系统暂态稳定性分析的发电机六阶数学模型、电动机二阶动态模型和恒功率静态模型相结合的综合负荷模型,以及具体的分析步骤.在舰船电力系统暂态稳定性分析中采用了适用于舰船电力系统暂态稳定的判据,并同时考虑了原动机、调速器和励磁器的...     

Targeted Silencing of MART-1 Gene Expression by RNA Interference Enhances the Migration Ability of Uveal Melanoma Cells

Uveal melanoma (UM) is the most common primary intraocular malignancy and the leading potentially fatal primary intraocular disease in adults. Melanoma antigen recognized by T-cells (MART-1) has been studied extensively as a clinically important diagnostic marker for melanoma, however, its biological function remains unclear. In the present study, the UM cell line SP6.5, which showed a high level of MART-1 expression, was subjected to small interfering RNA-mediated silencing of MART-1. Silencing of MART-1 expression increased the migration ability of SP6.5 cells and down-regulated the expression of the metastasis suppressor NM23. Our results suggest that MART-1 is a candidate target for the development of therapeutic strategies for UM and in particular for the suppression of metastasis associated with this malignancy.     

不同地下水位埋深下五道沟地区地表径流变化规律分析

基于五道沟实验站1991~1999年实测降水、地表径流及地下水位埋深资料,运用水文学原理及数理统计方法,选取不同降雨量和降雨类型,分析了不同量级降雨量、前期土壤干湿状态、次降雨过程砂姜黑土地表径流量及径流系数随地下水位埋深的变化规律。结果表明,对于砂姜黑土,在50mm以上日降雨过程中,存在土壤表层蓄满、深部超渗的分层产流机制;地表径流量及径流系数随地下水位埋深增加呈指数递减趋势,且随降雨量的增加地表径流系数呈上升趋势;而前期土壤干旱时间长、土壤含水率较低、地表径流系数随地下水位埋深增加而减少,且降雨集中分布比降雨分散分布的地表径流系数高。     

子宫动脉化疗栓塞联合清宫术在胎盘植入保守治疗中的应用

目的探讨子宫动脉灌注化疗栓塞联合清宫术治疗胎盘植入的可行性和安全性。方法２００６年１月至２０１０年６月在复旦大学附属妇产科医院就诊的２３例胎盘植入患者行子宫动脉化疗栓塞术,经双侧子宫动脉灌注ＭＴＸ各１００ｍｇ,庆大霉素８万ｕ,再以明胶海绵栓塞,术后３～１０ｄ行清宫术。结果子宫动脉化疗栓塞术手术成功率１００％。清宫术时出血４５～１９０ｍｌ,平均７８．５ｍｌ。无严重并发症发生。结论子宫动脉化疗栓塞配合清宫术可明显降低胎盘植入子宫切除和丧失生育能力的风险,是治疗胎盘植入安全可行的方法。     

Ⅰｂ２ ～ Ⅱａ期宫颈癌根治性子宫切除术前子宫动脉栓塞化疗及髂内动脉前干支化疗的疗效比较

目的探讨Ⅰｂ２～Ⅱａ期宫颈癌根治性子宫切除术前不同动脉化疗方式的近期及远期疗效。方法将１５１例患者分为研究组和对照组,研究组１１３例采取子宫动脉栓塞化疗术,对照组３８例采取髂内动脉前干支化疗,术后２～４周内行根治性子宫切除术,观察化疗后２周内肿瘤变化及根治性子宫切除术后２、５年生存率。结果介入术前测量肿瘤最大径平均为（４．５８±０．３７）ｃｍ,介入术后最大径平均值（２．１１±０．２４）ｃｍ。在研究组和对照组完全有效率分别为３１．９％和２１．１％;总有效率为９４．７％（１０７／１１３）和７６．３％（２９／３８）,２周内疗效研究组明显好于对照组（Ｐ值均＜０．０１）。两组手术切缘均未见癌浸润,研究组３例切缘见脉管转移,５例见宫旁浸润,盆腔淋巴结转移６例;对照组１例切缘脉管转移,２例宫旁浸润,１例盆腔淋巴结转移。研究组２年生存为６８／８４,５年生存为４７／６４;对照组２年生存２６／３２,５年生存１８／２４。两组２年及５年生存率比无明显差异（Ｐ值均＞０．０５）。结论子宫动脉化疗栓塞术短期内使宫颈癌肿瘤明显缩小,有利于外科手术剥离,近期疗效好于髂内动脉前干化疗,远期疗效无差异,是Ⅰｂ２～Ⅱａ期宫颈癌的首选新辅助动脉化疗方式。     

选择性输卵管造影及再通术在不孕症中的应用价值

目的评价选择性输卵管造影（ＳＳＧ）及再通术（ＦＴＲ）在输卵管不孕症中的疗效。方法经子宫输卵管造影证实４５９例患者共８９５条输卵管近端阻塞或通畅度不佳,将导管置于输卵管口,使用导丝疏通后造影,对比分析其手术前后输卵管通畅程度并随访１８个月内妊娠率。结果８９５条近端阻塞或不通畅输卵管疏通后５７２条（６３．９％）基本通畅。完全性阻塞输卵管ＳＳＧ及ＦＴＲ术后疏通率为８０．３％（５３／６６）;不完全性阻塞患者疏通率为９６．７％（８０２／８２９）。随访１８个月,２１２例患者中妊娠９３例（４３．９％）,异位妊娠２例（２．１％）。中位妊娠期为８．２个月。双侧输卵管基本通畅者妊娠率为５１．３％（５８／１１３）,双侧输卵管不完全通畅者妊娠率为３５．４％（３５／９９）。结论ＳＳＧ及ＦＴＲ安全有效,是治疗因输卵管近端阻塞或不通畅导致不孕的有效方法。     

测深仪失捕情况分析及解决途径

结合两例典型测深仪信号失捕情况,从船舶总体设计、测深仪型号选择和测深仪换能器安装等多方面分析了信号失捕产生的原因,提出了降低测深仪失捕率的几种基本途径。     

Conjugate free convection above a cooled finite horizontal flat plate embedded in a porous medium

We investigate conjugate free convection in a semi-infinite porous medium above a cold finite plate. Numerical solutions of the coupled governing equations for the fluid and the plate regions are obtained, and an analytical method is developed to predict the average temperature of the conjugate boundary and the Nusselt number.     

计及自由面兴波和螺旋桨非定常旋转效应的集装箱船舶绕流场计算研究

该文以商用软件FLUENT为平台,以KCS算例为对象,进行了计及自由面和螺旋桨非定常旋转效应的计算。考察了时间步长、自由面是否固化、湍流模式和网格数量、计算策略对计算结果的影响,确定了工程适用的计算方法,并应用于9000TEU集装箱船舶,与试验结果比较,吻合良好。