Visual Detection of Adenosine Triphosphate by Taylor Rising: A Simple Point-of-Care Testing Method Based on Rolling Circle Amplification

Rapid and sensitive point-of-care testing (POCT) is an extremely critical mission in practical applications, especially for rigorous military medicine, home health care, and in the third world. Here, we report a visual POCT method for adenosine triphosphate (ATP) detection based on Taylor rising in the corner of quadratic geometries between two rod surfaces. We discuss the principle of Taylor rising, demonstrating that it is significantly influenced by contact angle, surface tension, and density of the sample, which are controlled by ATP-dependent rolling circle amplification (RCA). In the presence of ATP, RCA reaction effectively suppresses Taylor-rising behavior, due to the increased contact angle, density, and decreased surface tension. Without addition of ATP, untriggered RCA reaction is favorable for Taylor rising, resulting in a significant height. With this proposed method, visual sensitive detection of ATP without the aid of other instruments is realized with only a 5 μL droplet, which has good selectivity and a low detection limit (17 nM). Importantly, this visual method provides a promising POCT tool for user-friendly molecular diagnostics.     

微分中值定理在复数域内的推广

应用解析函数的无穷可微性及积分估值定理和牛顿-莱布尼兹公式等证明了La-grange中值定理、Cauchy中值定理、L’Hospital法则在复数域内的相应推广定理,并说明了实函数与复变函数之间产生区别的根源.     

基于S变换的全桥整流电路故障诊断研究

针对应用广泛的全桥整流电路故障分析,根据整流电压波形的畸变规律,分析了2个以内的二极管故障分为7类共计22种故障元。运用S变换分析,提取了故障特征值,并以此构造故障模式向量作为RPORP神经网络的输入。实现了电路的故障诊断与定位。为双凸极发电机整流电流故障的进一步研究打下了基础。     

广义Jensen-Schur测度在医学图像配准中的应用

使用互信息或归一化互信息测度进行医学图像配准时,由于噪声、模态、插值等影响,测度函数存在许多局部极值,收敛范围较窄,有可能导致误配准。为了克服上述缺点,定义了广义Jensen-Schur测度,利用巴特沃思函数对自变量值的非线性压缩功能,成功地消除了PV插值伪极值点。从测度曲线光滑性、抗噪鲁棒性、收敛性能方面,对四种新构造的广义Jensen-Schur测度、互信息和归一化互信息进行了比较和分析。实验结果表明,新构造的JS22和JS23测度在以上三个方面的性能都优于其他测度。     

SO2浓度智能检测仪的设计

SO2可导致酸雨形成,同时在一定条件下还可破坏臭氧层以及产生光化学烟雾等,对生态环境有很大的破坏作用,所以必须对SO2进行严格的检测和控制;本设计在学习研究了电化学SO2传感器的检测原理的基础上,完成了基于电化学传感器的烟气SO2浓度智能检测仪,完成了对烟气SO2浓度智能检测仪的气路部分和电路部分的设计;论文内容包括检测仪的工作原理、气路设计传感器的检测原理及相关电路的设计,还完成了软件设计和通信接口的设计,并对实验结果进行分析;该设计实现计算机智能化处理,能够广泛应用在工矿企业和大气的SO2浓度的检测。     

Monolithically integrated CoP nanowire array: An on/off switch for effective on-demand hydrogen generation via hydrolysis of NaBH<Subscript>4</Subscript> and NH<Subscript>3</Subscript>BH<Subscript>3</Subscript>

The issues of hydrogen generation and storage have hindered the widespread use and commercialization of hydrogen fuel cell vehicles.It is thus highly attractive,but the design and development of highly active non-noble-metal catalysts for on-demand hydrogen release from alkaline NaBH4 solution under mild conditions remains a key challenge.Herein,we describe the use of CoP nanowire array integrated on a Ti mesh (CoP NA/Ti) as a three-dimensional (3D) monolithic catalyst for efficient hydrolytic dehydrogenation of NaBH4 in basic solutions.The CoP NA/Ti works as an on/off switch for on-demand hydrogen generation at a rate of 6,500 mL/(min.g) and a low activation energy of 41 kJ/mol.It is highly robust for repeated usage after recycling,without sacrificing catalytic performance.Remarkably,this catalyst also performs efficiently for the hydrolysis of NH3BH3.     

复杂产品虚拟样机协同开发平台设计与实现

提出复杂产品虚拟样机协同开发平台的体系结构和功能框架,设计统一数据访问接口,自主开发了“复杂产品虚拟样机协同开发平台”软件。该软件包括个人工作空间管理、仿真建模、数据管理、过程管理、模型库管理和仿真评估等功能模块,能够支持复杂产品从设计、仿真、分析和优化的整个多学科协同开发过程,实现了对协同开发相关的项目、人员、模型、数据和工作流等资源的集成化管理,为复杂产品虚拟样机的实施提供了设计、仿真和资源管理的分布式支撑环境。     

氧化亚铜微米晶的水热合成与生长机理

氧化亚铜是一种重要的P型半导体材料，目前因其独特的可见光催化性能在科研领域引起了广泛的重视。以CuSO4·5H2O为铜源，以α—D-葡萄糖为还原剂，并利用水热还原反应合成出了不同形貌的Cu2O微米晶。利用X射线粉末衍射分析（XRD）、透射电子显微镜（TEM）对合成的样品进行了形貌与结构的表征与分析。结果表明所合成的晶粒尺寸均匀且分散性好。讨论了不同条件下的晶粒生长机理，运用扩散机制与聚集机制解释了不同形貌的成因。     

Diffraction field of tightly focused laser beams and its influence to laser accelerator

In this paper, we have studied the dynamic characteristics of relativistic electron injected into stationary intense vacuum laser fields. We found the dynamic trajectories can basically be classified as three categories, namely Inelastic Scattering (IS), Capture and Acceleration Scenario (CAS) and Penetrate into Axial Region and Move (PARM) trajectory. The physical mechanism as to the three kinds of electrons have been examined. In particular, the PARM trajectory which we presented in this paper is different from the CAS and IS trajectory which we had already found in our previous work. We will show the PARM stems from the strong diffraction effect of a tightly focused laser field. In addition, the initial condition for the three kinds of electrons to emerge were detailed investigated. It has been found that there are four factors which chiefly decide the appearance of the three kinds of dynamics trajectories, namely the laser beam width w₀ and intensity a₀, the electrons incident angle θ and initial transversal momentum p_ti. The implication of the PARM electrons to the planned vacuum laser accelerators is illustrated.     

等离子喷涂W-Cu电子封装材料的组织与性能

采用等离子喷涂工艺制备了W-Cu电子封装材料，并对该电子封装材料的微观组织和热物理性能进行了研究．结果表明，在内部送粉条件下，复合材料中钨的收得率要高于外部送粉条件下复合材料中钨的收得率；在内部送粉条件下，功率对铜氧化的影响并不明显；而在外部送粉条件下，随着功率的提高，铜的氧化明显增多；由于氧化物和孔隙等的存在，利用大气等离子喷涂工艺制备的复合材料的导热率远远低于根据混合法则计算的理论值．这为后续实验研究提供了重要的参考依据．