Silicon-Doped Titanium Dioxide Nanotubes Promoted Bone Formation on Titanium Implants

While titanium (Ti) implants have been extensively used in orthopaedic and dental applications, the intrinsic bioinertness of untreated Ti surface usually results in insufficient osseointegration irrespective of the excellent biocompatibility and mechanical properties of it. In this study, we prepared surface modified Ti substrates in which silicon (Si) was doped into the titanium dioxide (TiO₂) nanotubes on Ti surface using plasma immersion ion implantation (PIII) technology. Compared to TiO₂ nanotubes and Ti alone, Si-doped TiO₂ nanotubes significantly enhanced the expression of genes related to osteogenic differentiation, including Col-I, ALP, Runx2, OCN, and OPN, in mouse pre-osteoblastic MC3T3-E1 cells and deposition of mineral matrix. In vivo, the pull-out mechanical tests after two weeks of implantation in rat femur showed that Si-doped TiO₂ nanotubes improved implant fixation strength by 18% and 54% compared to TiO₂-NT and Ti implants, respectively. Together, findings from this study indicate that Si-doped TiO₂ nanotubes promoted the osteogenic differentiation of osteoblastic cells and improved bone-Ti integration. Therefore, they may have considerable potential for the bioactive surface modification of Ti implants.     

MC6845在工业控制机中的应用

MC68 4 5是Motorola生产的一种 4 0引脚的双列直插式可编程器件 ,阐述了一种用MC684 5制作的工业控制机图形显示模板的电路原理 ,其设计思路对从事这方面的开发和应用都会有所启发。     

Bifunctional Opioid/Melanocortin Peptidomimetics for Use in Neuropathic Pain: Variation in the Type and Length of the Linker Connecting the Two Pharmacophores

Based on the mechanism of neuropathic pain induction, a new type of bifunctional hybrid peptidomimetics was obtained for potential use in this type of pain. Hybrids consist of two types of pharmacophores that are connected by different types of linkers. The first pharmacophore is an opioid agonist, and the second pharmacophore is an antagonist of the pronociceptive system, i.e., an antagonist of the melanocortin-4 receptor. The results of tests in acute and neuropathic pain models of the obtained compounds have shown that the type of linker used to connect pharmacophores had an effect on antinociceptive activity. Peptidomimetics containing longer flexible linkers were very effective at low doses in the neuropathic pain model. To elucidate the effect of linker lengths, two hybrids showing very high activity and two hybrids with lower activity were further tested for affinity for opioid (mu, delta) and melanocortin-4 receptors. Their complexes with the target receptors were also studied by molecular modelling. Our results do not show a simple relationship between linker length and affinity for particular receptor types but suggest that activity in neuropathic pain is related to a proper balance of receptor affinity rather than maximum binding to any or all of the target receptors.     

GC/MC法分析哈尔滨风干肠香辛料中的挥发性成分

为了获取关于香辛料在哈尔滨风干肠中的应用资料,利用静态顶空进样法从哈尔滨市售两种知名品牌的风干肠香辛料（FX）中收集到挥发性香气成分,连接GC／MC装置进行分析,分别测得FX1中有20种化合物,FX2中有22种化合物,这些化合物均以烯烃类、醇类、醚类、醛类、酮类、酸类、脂类及芳香类有机化学物质为主,而此类化学物质也均属于食品化学中所介绍的香辛料的主要成分的范畴,本实验利用峰面积归一化法通过G170LBA化学工作站数据处理系统得出各化学成分在每个样品中的相对百分比。     

换流可靠的双电压合成矩阵变换器的仿真

矩阵变换器是一种交-交变换器,由于没有中间直流环节,输入侧和输出侧相互影响较大。文中讨论了利用输入电压瞬时值进行调制的双电压合成原理,并结合其特点,提出了通过调整开关顺序来提高换流可靠性的优化方法,利用M atlab/S im u link建立了相应的仿真模型,仿真结果验证了所提出方法的正确性。     

ZigBee技术在远程抄表系统中的应用

将无线射频芯片与单片机系统相结合,可以实现无线远程水表控制和对流量数据的读取,该系统通过射频收发模块实现数据的传输。本文重点介绍以Freescale公司生产的MC9S08GB60单片机和MC13192射频收发模块为核心的远程抄表系统的硬件电路以及软件流程设计。     

Uplink performance of CWP-MC-CDMA with Space Diversity Combining technique over Rayleigh fading channel

In this paper, a Complex Wavelet Packet （CWP-MC-CDMA） system uplink model is proposed, based Multi-Carrier Code Division Multiple Access based on the analysis of the principle of MC-CDMA and the use of the optimized complex wavelet packet. Considering that the base station can adopt multiple re- ceiver antennas in the uplink, we employ the Space Diversity Combining （SDC） technique to improve the sys- tem pertbrmance via multiple antennas. The uplink performance of proposed CWP-MC-CDMA system with SDC technique is investigated over Rayleigh lading channel, and corresponding bit error rate analysis is given in detail. The system can avoid the decrease of spectrum efficiency of conventional MC-CDMA due to inserting cyclic prefix. Theoretical analysis and simulation result show that the application of SDC technique can improve the CWP-MC-CDMA system ability to combat spatial lading and various interferences effectively. Moreover, the proposed system based on SDC technique has superior Bit Error Rate （BER） performance over the Discrete Fourier Transform （DFT） and SDC based MC-CDMA system and the real wavelet packet and SDC based MC-CDMA system.     

远程水声通信的MC-MPSK方法

远程水声信道是多途、时变、强环境噪声干扰的信道,声波在其中的传输行为十分复杂,加之水声传输的带宽有限以及通信载波频率较低,使得水声通信传输距离和数据率这一对矛盾尤为突出。如何在增大作用距离的同时提高传输数据率是水声通信的难点。该文在80km海上试验的基础上,提出了适合于远程水声通信的多载波-多相移键控（MC-MPSK）的编码调制解调方法。该方法采用多个载波同时进行多相位调制,即信号的频率和相位同时携带信息。该方法与梳状均衡器结合可在增大作用距离的同时提高传输数据率。对不同多径信道模型,相对运动速度10m／s,不同SNR下的误比特率进行的仿真结果表明,该编码调制解调方法可实现远程、多径水声信道的高数据率传输,并进行了湖试验证。     

等值面抽取技术在超声探头声场模拟中的应用

为了更好地研究超声波声场,提出了以等值面方式来表现超声探头的声场分布;运用并改进了经典的MC（Marching Cubes）算法得出了圆盘和矩形两种超声探头声源的三维声场等值面描述.实验表明改进后的算法能获得较好的效果.     

添加矿物型MC凝聚剂实现煤泥水深度澄清的实验室试验

重点介绍矿物型MC凝聚剂和阴离子型聚丙烯酰胺絮凝剂联合添加促进煤泥水澄清的实验室试验过程及相关分析,试验的特点是用分光光度计和电导率仪进行模拟性试验。试验结果表明,采用MC凝聚剂能高效获得极为清净的澄清水。