Evaluation of different coating systems by electrochemical methods

Corrosion protection of organic coated steel is determined by free corrosion potential measurements and impedance spectroscopy. The results are classified by means of very basic considerations and evaluation figures are developed. These electrochemical data are correlated with the extent of the corrosion for each coating system. The evaluation figures are used for ranking coating systems and this ranking is correlated with the ranking with reference to the results of standardized and exposure tests.     

层次式级联多网络模型及其性能

本文提出了一种层次式级联多网络结构，论述了其训练算法，并验证了该结构的收敛性。这种结构在处理高阶非线性分布数据的分类问题方面具有优良的性能，用北京谱仪事例过滤进行性能测试结果表明，其训练和泛化性能都优于单个ＢＰ网络。     

加速器磁场测量的霍尔多探头装置

描述了用于加速器磁场测量的霍尔多探头装置,它包括一个具有三只恒温盒(内有58只霍尔片)的测磁长臂,高精度磁场检定系统以及数据自动获取系统。分别叙述了霍尔片的定位、恒温、校准、数据采集、处理等内容。并提出了多探头装置测量中霍尔片稳定性的重要性。给出了在我们条件下的一些具体数据。本装置已应用在兰州重离子研究装置(HIRFL)的建造过程中,实践证明它能有效地高质量地满足加速器磁场测量的要求。     

An analytical and numerical study of the two-dimensional Bratu equation

Bratu's problem, which is the nonlinear eigenvalue equationu+ exp(u)=0 withu=0 on the walls of the unit square and as the eigenvalue, is used to develop several themes on applications of Chebyshev pseudospectral methods. The first is the importance ofsymmetry: because of invariance under the C₄ rotation group and parity in bothx andy, one can slash the size of the basis set by a factor of eight and reduce the CPU time by three orders of magnitude. Second, the pseudospectral method is ananalytical as well as a numerical tool: the simple approximation3.2A exp(–0.64A), whereA is the maximum value ofu(x, y), is derived via collocation with but a single interpolation point, but is quantitatively accurate for small and moderateA. Third, the Newton-Kantorovich/Chebyshev pseudospectral algorithm is so efficient that it is possible to compute good numerical solutions—five decimal places—on amicrocomputer inbasic. Fourth, asymptotic estimates of the Chebyshev coefficients can be very misleading: the coefficients for moderately or strongly nonlinear solutions to Bratu's equations fall off exponentially rather than algebraically withv untilv is so large that one has already obtained several decimal places of accuracy. The corner singularities, which dominate the behavior of the Chebyshev coefficients in thelimit v, are so weak as to be irrelevant, and replacing Bratu's problem by a more complicated and realistic equation would merely exaggerate the unimportance of the corner branch points even more.     

Adenovirus-Mediated Inducible Expression of a PD-L1 Blocking Antibody in Combination with Macrophage Depletion Improves Survival in a Mouse Model of Peritoneal Carcinomatosis

Immune checkpoint inhibitors (ICIs) have demonstrated remarkable efficacy in a growing number of malignancies. However, overcoming primary or secondary resistances is difficult due to pharmacokinetics issues and side effects associated with high systemic exposure. Local or regional expression of monoclonal antibodies (mAbs) using gene therapy vectors can alleviate this problem. In this work, we describe a high-capacity adenoviral vector (HCA-EFZP-aPDL1) equipped with a mifepristone-inducible system for the controlled expression of an anti-programmed death ligand 1 (PD-L1) blocking antibody. The vector was tested in an immune-competent mouse model of colorectal cancer based on implantation of MC38 cells. A single local administration of HCA-EFZP-aPDL1 in subcutaneous lesions led to a significant reduction in tumor growth with minimal release of the antibody in the circulation. When the vector was tested in a more stringent setting (rapidly progressing peritoneal carcinomatosis), the antitumor effect was marginal even in combination with other immune-stimulatory agents such as polyinosinic-polycytidylic acid (pI:C), blocking mAbs for T cell immunoglobulin, mucin-domain containing-3 (TIM-3) or agonistic mAbs for 4-1BB (CD137). In contrast, macrophage depletion by clodronate liposomes enhanced the efficacy of HCA-EFZP-aPDL1. These results highlight the importance of addressing macrophage-associated immunoregulatory mechanisms to overcome resistance to ICIs in the context of colorectal cancer.     

红外测温技术在离心复合铸造轧辊生产上的应用

本文分析了离心复合铸造轧辊生产过程中离心机停机温度和时间对轧辊质量的影响 ,提出了用先进的红外测温技术来预报停机温度和时间 ,以实现微机监控适时停机 ,保证轧辊内外层熔合良好 ;同时指出了红外测温技术在离心复合铸造轧辊生产上的应用前景     

NANO-MULTILAYERS WITH HIGH PERPENDICULAR ANISOTROPY FOR MAGNETIC RECORDING

(FePt/Ag)n nano-multilayers were deposited on MgO (100) single crystal with laser ablation and then subjected to annealing. FePt L1o grains with (001) texture and thus a large perpendicular magnetic anisotropy constant Ku of the order of 106 J/m3 were formed. A thick Ag layer is found to be favorable for decreasing the dispersion of the easy axis for magnetization. The measurement of time decay of magnetization gave rise to a small activation volume of the order of 10-25m3, showing the promising of being the recording medium for future high density perpendicular recording.     

磁性材料产业现状与展望

介绍磁性材料的主要品种，如永磁体、软磁体和磁记录介质材料的行业现状及技术进步。     

关于煤炭硫分分级的探讨

根据国家质量技术监督局的计划安排,国家标准GB／T15224－1994《煤炭质量分级》需要修订。本文主要讨论“煤炭硫分分级”方面的内容。