陶建地面区域时问同步监测系统的研究

为了实现监测网内被授时设备的时间同步及对授时设备状态（时间源信息、板卡信息、报警信息等）、被授时设备时间信息（与授时设备间的时间偏差）等信息,通过在数据网上构建地面区域时间同步监测系统的方法,配置时间同步系统设备和时间时间同步监测系统设备。采用数据网传输PTP时间同步报文并对电力二次设备授时状态进行监测,达到了较高的时间输出精度和监测信息的精度。     

Design,Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2

Over expressing in PTPN1 (encoding Protein tyrosine phosphatase 1B, PTP1B), a protein tyrosine phosphatase (PTP) that plays an overall positive role in insulin signaling, is linked to the pathogenesis of diabetes and obesity. The relationship between PTP1B and human diseases exhibits PTP1B as the target to treat these diseases. In this article, small weight molecules of the imidazolidine series were screened from databases and optimized on silicon as the inhibitors of PTP1B based on the steric conformation and electronic configuration of thiazolidinedione (TZD) compounds. The top three candidates were tested using an in vitro biological assay after synthesis. Finally, we report a novel inhibitor, Compound 13, that specifically inhibits PTP1B over the closely related phosphatase Src homology 2 (SH2) domain-containing phosphatase 2 (SHP-2) at 80 μM. Its IC₅₀ values are reported in this paper as well. This compound was further verified by computer analysis for its ability to combine the catalytic domains of PTP1B and SHP-2 by molecular dynamics (MD) simulations.     

预防药用PTP包装误服标识设计研究

针对国内药用PTP包装误服情况,分析预防药物PTP包装误服标识设计的必要性,结合国外设计经验论述了图形标识与药品包装的关系,利用标识设计实际案例及相关问卷调查分析,验证国内药用PTP包装标识设计的可行性。提出了利用标识设计可以改善药物识别性,通过药用包装标识来加强消费者自我药疗及呼吁制药方改善对药品制造等安全策略。     

IEEE1588时钟同步在PTN网中的实现

详细分析了IEEE1588时钟同步的基本原理,介绍了阿尔卡特朗讯TSS-5产品中实现IEEE1588时钟同步系统的方案,给出具体的硬件架构框图以及系统功能框图,最后列出TSS-5网元在实验室做的时间性能实验。实验结果表明TSS-5时钟同步具有稳定的性能,同步精度达到亚微秒级,可满足PTN产品高精度时钟同步的要求。     

分组网中的IEEE1588v2同步技术及应用

介绍了＂ALL IP＂背景下分组网络作为统一承载网络面临的同步需求,以及分组网络的频率和时间同步实现技术和网络应用方案。     

使用JMS构造J2EE的异步通信构架

互联网的出现极大地方便了人们的工作和生活,同时也提出了一个新的课题,即如何在现有的条件下,开发出在用户可以接受的响应时间范围内,通过互联网来实现交互的应用.由于种种原因,现有的大部分应用在响应速度方面都存在一些问题,这些问题可能是网络带宽不够造成的,也有可能是传输的数据量太大造成的,还有可能是和系统交互的外部系统处理时间过长造成的.文章针对最后这种情况,提出在J2EE环境下的一种异步通信方案,来缓解这个问题.     

A fuzzy-based decision-making method for evaluating product discontinuity at the product transition point

Companies have been striving to achieve product innovation and cost savings to keep up with a rapidly changing manufacturing environment, as well as to deliver new products just in time and earlier than their competitors. Their strategic goals include effective decision making with regard to product life cycles, predicting market demand, and timing new product launches through the optimization of demand and supply of products. However, most products that enter a decline stage experience a decline in sales, which in turn causes an increase in warehouse costs, and a decline in competitiveness, owing to a delay in the release of new products. In this paper, we propose a fuzzy-based decision-making method to effectively evaluate products to be discontinued at the product transition point after taking into account market uncertainties and characteristics of businesses in companies. Therefore, we conduct the matrix analysis and the Pareto analysis for quantitative evaluation of four stages of the product life cycle based on market demand information for target product groups, apply the results of this analysis to the fuzzy-based qualitative evaluation model, and subsequently infer the discontinuity priority for product models that are expected to be replaced by new products. Furthermore, we develop the PTP portfolio system to identify a list of product models to be discontinued, as well as to review their percentage of sales contribution with respect to the overall product sales of the company.     

基于PTP协议时钟同步系统的实现

由于校区的扩大,对时钟精度的要求越来越高。为了解决这个问题,采用基于PTP协议的时钟同步系统来实现对时钟的精确同步控制,确保了校区内时间的同步性和精确性。     

基于IEEE1588的智能变电站时钟同步技术

随着IEC61850标准在智能变电站领域的推广应用,智能电子设备IED（Intelligent Electronic Device）对时钟精度要求已达到了T5等级（1μs）.介绍IEEE 1588时间同步原理,对研制的PTP 925d时钟模块进行性能测试,证明在硬件辅助条件下IEEE 1588标准的时间同步精度可以达到纳秒量级.并分析IEC 61850标准在智能变电站的功能结构,以PTP 925d时钟模块为基本构件,设计智能变电站站内与站间的PTP时间同步方案,论述与分析相关技术细节,为IEEE 1588在智能变电站的工程应用提供参考.     

On-line collision avoidance system for two PTP command-based manipulators with distributed controller

This research aims to solve online collision avoidance problem of two manipulators with independent controller. Since industrial robot controller is a closed commercial system, trajectory generation part of robot controlling is always proprietary or unknown. Thus, this paper proposes a collision avoidance system of two manipulators which are controlled by point-to-point (PTP) commands, in condition that the internal of robot controller is unknown and unchangeable. Based on this condition, collision avoidance is supposed to be realized by online scheduling of these PTP controlling commands. This paper proposes the collision avoidance method that assumes the three-dimensional common workspace between two manipulators can be partitioned into many subregion elements. And with managing these subregion elements, which are occupied by robot motion, PTP commands are scheduled to adjust execution timing for collision avoidance. A deadlock problem caused by the partition of the workspace is also taken into consideration in the method. And the effectiveness and efficiency of the method have been verified by simulations and experiments.