Application of a Compaction Simulator to the Design of a High-Dose Tablet Formulation. Part I

The compaction properties of an investigational drug are studied by the use of a compaction simulator. The effects of punch velocity over the range of 30-640 mm^-1 on the compaction properties of the pure drug and a variety of formulas incorporating a high dose of the active compound have been investigated. The data were analyzed by applying the Heckel equation. The pure drug was found to have a high yield pressure at a relatively low punch velocity of 31 mm^-1. As the punch velocity was increased there was a decrease in crushing strength, primarily as a result of increasing yield pressure. These findings indicate that the pure drug predominantly consolidated by fragmentation and elastic deformation, with a slow plastically deforming component. The information obtained on the consolidation mechanism of the pure drug and, subsequently, on model formulas were instrumental in the design and selection of a robust formula and granulation process. The advantages of conducting dosage form design and characterization studies during the early phase of tablet formulation using means such as a compaction simulator are emphasized in this investigation.     

沼气汽车加气站的探讨

分析了适合于汽车加气用沼气的品质，就沼气汽车加气站的流程、设备选型等进行了论述。     

模内贴箔装饰的自动化生产

详细介绍了一种新型装饰工艺－模内贴箔工艺的自动化过程及生产要求。     

凤滩水电厂自动发电控制策略

介绍了凤滩水电厂自动发电控制(AGC)策略的实现方法,重点介绍了修正等容量比例有功分配方法及相应措施.程序设计的原则是,机组紧跟目标负荷的情况下,在最佳效率下运行,同时减少机组开/停机次数、有功调节频率和跨越振动区次数,从而减少机组磨损,兼顾运行效率和机组运行安全.     

The application of microencapsulated phase‐change materials to nylon fabric using direct dual coating method

The fabrication of functional textiles able to provide thermal regulation and comfort for the body has attracted increasing interest in recent years. This research investigated fabric coatings containing energy absorbing, temperature stabilizing, phase‐change material microcapsules (PCMMcs), and their methods of application. Specifically, a coated fabric was directly prepared by a dual‐type coating method, in which the PCMMcs were dispersed in a polyurethane coating solution with no binder. The thermal performances of the dual‐coated samples were evaluated by differential scanning calorimetry, and their physical characteristics were examined by scanning electron microscopy, thermal vision camera, porosity, water vapor transmission rate (WVTR), and water entry pressure (WEP) analyses. Furthermore, the microclimate characteristics of the thermally enhanced fabrics were investigated under experimental conditions using a human‐clothing‐environment (HCE) simulator system. The study results confirmed the superior performance of the dual‐coated fabrics in terms of thermal regulation and body comfort, compared with those coated by the dry or wet coating method, because of the improved WEP, WVTR, and thermal performance. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

小容量机组保护监控一体化

以数字信号处理器(DSP)和复杂可编程逻辑器件(CPLD)为硬件平台,研制了新一代面向中、小型水电站的综合自动化模块.充分发挥MB40智能可编程逻辑控制器(iPLC)及MB100系列保护测控系统的技术优势,将小型水电站的保护装置做成模块插件,融入监控系统,降低了小型水电站自动化设备的成本,为推出真正意义上的面向小型水电站的"五合一"产品打下坚实的基础.     

瓶组气化站的建筑、结构设计要点

瓶组气化站的建筑，结构设计关系到安全，满足使用要求和投资的大小，本文根据多年的实践和最新的有关设计规范的要求，阐述瓶组气化站建筑，结构设计的要点。     

北京核电站模拟器硬件的功能和特点

本文介绍北京核电站模拟器硬件构成并分析其功能和特点。     

秦山300MW核电机组全范围仿真机测试验收

介绍了秦山３００ＭＷ核电机组全范围仿真机的测试验收的整个过程，包括：验收测试规程的形成，工厂内部预测试和工厂用户测试。并分析了测试验收过程中存在的重大问题及解决的办法。     

可视化基站发电管理系统

针对以前的发电管理系统或只是数据呈现,提供市电及发电相关数据信息,或只是提供出车轨迹,主要实现对出车的管理,不能全面反应发电全过程且不便于对发电事件进行分析的情况,提出可视化发电管理系统的概念。在简要介绍了LBS系统、动力环境监控系统后,讲述了可视化基站发电管理系统的组成以及通过LBS定位管理、短信互动、实时监测数据等进行系统实现。可视化发电管理系统通过可视化的界面帮助发电管理人员进行管理,直观、便捷。