基于可见光-近红外新光谱特征和最优组合原理的大麦叶片氮含量监测

提出新的作物冠层叶片氮含量(LNC)高光谱遥感监测方法,以对氮素要求较高的大麦LNC监测为例,利用田间实测数据,从可见光－近红外区域的高光谱反射曲线中提取包含丰富多波段信息的斜率、夹角等新型特征参数,应用组合预测领域中的权重最优组合原理及其算法,实现对作物LNC的高光谱监测.研究表明,提出的高光谱反射曲线斜率和夹角等新型特征参数与作物LNC显著相关,并具有较好的定量响应关系,其中关键斜率参数(Kre/Kpb)和Kpb以及夹角参数(Aδ/Aα)和(Aδ/Aθ)较好地描述了LNC的动态变化; 而权重最优组合分析则表明(Kre/Kpb)和Knir1两个参数的组合最能响应LNC的光谱信息,有助于增强监测的稳定性并提高估测的精度.     

有线无线组合通信的便携式哨兵报警对讲系统

针对哨兵离开哨位处置突发警情时哨兵与值班室的联系中断这一问题,采用以有线通信和无线通信组合的方式设计了便携式哨兵报警对讲系统,实现哨兵离开哨位时与值班室的语音对话,同时实现哨兵遇到紧急情况无法进行语音对话时的紧急报警以及当哨兵遭到袭击倒地的自动检测报警。     

Smart Injectable Hydrogels for Cancer Immunotherapy

Hydrogels, a class of materials with a 3D network structure, are widely used in various fields especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and controlled release of small molecular drugs, macromolecular therapeutics, and even cells. With the rapid development of cancer immunotherapy, such injectable hydrogels have attracted wide attention for local immunomodulation to boost systemic anticancer immune responses, realizing more effective immunotherapy at lower doses. The latest progresses in the development of various smart injectable hydrogels for cancer immunotherapy are summarized here. Although applied locally, such injectable hydrogels can activate systemic antitumor immune responses, safely and effectively inhibiting the tumor metastasis and recurrence. Moreover, it is discussed how injectable hydrogel‐based cancer immunotherapy would contribute to the development of next generation of cancer treatment together with their potential for clinical translation.     

Biodegradable Nanoscale Coordination Polymers for Targeted Tumor Combination Therapy with Oxidative Stress Amplification

Nowadays various inorganic nanoparticles that generate highly reactive hydroxyl radical ( · OH) on the basis of Fenton‐like catalytic activity of metal ions have been designed for chemodynamic therapy. However, the high level of adaptive antioxidants [glutathione (GSH)] in cancer cells could effectively consume · OH to compromise the treatment efficiency and biosafety of these inorganic nanoparticles, and this is a general concern in chemodynamic therapy. Herein, a new biodegradable nanoscale coordination polymer (NCP) is developed by integration of cisplatin prodrug (DSCP) and iron (III) ions through a reverse microemulsion method. The DSCP in the NCPs could react with GSH to release free cisplatin, while the iron (III) ions could be reduced by GSH into iron (II) to enable Fenton reaction, subsequently leading to amplified intracellular oxidative stress. After surface modification of polyethylene glycol (PEG) and cyclo[Arg‐Gly‐Asp‐D‐Phe‐Lys(mpa)] peptide (cRGD), Fe‐DSCP‐PEG‐cRGD shows an excellent targeting effect against α_vβ₃‐integrin overexpressed tumor cells. Furthermore, Fe‐DSCP‐PEG‐cRGD enables significant chemo and chemodynamic therapy with dramatically enhanced therapeutic efficiency in comparison to relative monotherapies. Importantly, Fe‐DSCP‐PEG‐cRGD could be efficiently cleared out from mice through feces and urine postinjection 7 days. The NCP presented in this work is simple and economical, which shows great biodegradability and biosafety for potential clinical translation.     

Efficient recursive least squares parameter estimation algorithm for accurate nanoCMOS variable gain amplifier performances

ABSTRACT

With the aggressive scaling of integrated circuit technology, parametric estimation is a critical task for designers who looked for solutions to the challenges of some Nanoscale CMOS parameters. This paper presented the prediction of primary parameters of CMOS transistor for 16 nm to 10 nm process nodes using both of Bisquare Weights (BW) method and a novel recursive least squares (RLS) parameter estimation algorithm. The proposed RLS algorithm consists of the minimisation of a quadratic criterion relating to the prediction error in order to attain the best estimated parameters of the developed mathematical model. The obtained results thanks to the proposed RLS algorithm were better than those reached using the BW method. Comparisons between Predictive Technology Model (PTM) data and parameters estimated with RLS algorithm were made to check the validity and the consistency of the proposed algorithm. These predicted primary parameters were helpful to estimate and to optimise the performances of the Variable Gain Amplifier (VGA) which was a basic circuit element with a key role in the design of new upcoming receivers.     

高职院校工学结合中思政教育问题及对策分析

工学结合已成为职业教育一种重要的实用型人才培养模式。新时代的工学结合培养模式对高职院校思政教育提出了新要求。深入分析当前工学结合中思政教育所面临的困难, 便于针对性提出解决问题的对策, 为高职院校更好地开展思政教育提供参考。     

酸雾测定仪在选择酸洗添加剂中的应用

介绍自行设计的一套酸洗酸雾检测仪及其操作，以及在选择酸洗添加剂中的应用。     

基于RCM 的导弹装备最佳预防性维修周期决策

针对目前确定预防性维修周期时存在不确定性的问题,建立了基于RCM的导弹装备维修周期决策模型。分别以总费用最小和可用度最大为目标建立导弹装备维修周期决策模型,采用蒙特卡罗仿真进行模型求解,采用模糊决策方法确定多目标综合最佳预防性维修周期,并以某型导弹装备密封圈为例,验证方法的有效性。实践分析结果表明:该方法综合权衡了费用和可用度因素,能较好地解决可用度低下且维修费用居高不下的问题,有一定应用和参考价值。     

信息检索结果隐式多样化排序方法研究

针对信息检索隐式多样化算法展开研究。介绍了检索结果重排序中的最大边际相关度(MMR)算法、相对熵(KL)算法、现代投资组合理论(MPT)3个隐式多样化算法,采用此3个算法对所选的已排序的文档数据集进行重排,通过对排序结果进行评价来对比三者的性能。得出隐式多样化方法中当相关性和多样性以一定比例的线性组合时,会使最终的检索结果在一些评价指标上相对于原始结果有所提高。     

ERP带来的新管理模式与中国式管理相结合的探索

介绍了ERP系统的设计特点,详细阐述了ERP系统所带来的积极变化,并从文化冲突的角度上分析了ERP系统实施中遇到的阻力。为了解决该困难,文中初步提出了ERP系统管理软件与中国式管理思想相融合的假设。