基于模糊谱聚类的不确定蛋白质相互作用网络功能模块挖掘

针对谱聚类融合模糊C-means（FCM）聚类的蛋白质相互作用（PPI）网络功能模块挖掘方法准确率不高、执行效率较低和易受假阳性影响的问题，提出一种基于模糊谱聚类的不确定PPI网络功能模块挖掘（FSC-FM）方法。首先，构建一个不确定PPI网络模型，使用边聚集系数给每一条蛋白质交互作用赋予一个存在概率测度，克服假阳性对实验结果的影响；第二，利用基于边聚集系数流行距离（FEC）策略改进谱聚类中的相似度计算，解决谱聚类算法对尺度参数敏感的问题，进而利用谱聚类算法对不确定PPI网络数据进行预处理，降低数据的维数，提高聚类的准确率；第三，设计基于密度的概率中心选取策略（DPCS）解决模糊C-means算法对初始聚类中心和聚类数目敏感的问题，并对预处理后的PPI数据进行FCM聚类，提高聚类的执行效率以及灵敏度；最后，采用改进的边期望稠密度（EED）对挖掘出的蛋白质功能模块进行过滤。在酵母菌DIP数据集上运行各个算法可知，FSC-FM与基于不确定图模型的检测蛋白质复合物（DCU）算法相比，F-measure值提高了27.92%，执行效率提高了27.92%；与在动态蛋白质相互作用网络中识别复合物的方法（CDUN）、演化算法（EA）、医学基因或蛋白质预测算法（MGPPA）相比也有更高的F-measure值和执行效率。实验结果表明，在不确定PPI网络中，FSC-FM适合用于功能模块的挖掘。     

When Teachers' and Parents' Values Differ: Teachers' Ratings of Academic Competence in Children From Low-Income Families.

The authors examined predictors of teachers' ratings of academic competence of 105 kindergarten children from low-income families. Teachers rated target children's expected competence in literacy and math and completed questions about their perceptions of congruence-dissonance between themselves and the child's parents regarding education-related values. Independent examiners assessed children's literacy and math skills. Teachers' instructional styles were observed and rated along dimensions of curriculum-centered and student-centered practices. Controlling for children's skills and socioeconomic status, teachers rated children as less competent when they perceived value differences with parents. These patterns were stronger for teachers who exhibited curriculum-centered, rather than student-centered, practices. The findings suggest a mechanism by which some children from low-income families enter a path of diminished expectations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

比较法在房地产开发中的应用

对"比较法"原理和应用情况进行了分析,说明其在房地产开发中能够科学地预测房地产的价格和收益,从而提高财务分析的科学性和权威性,为项目决策提供科学依据,以促进"比较法"在房地产开发中的应用。     

关于征地制度的思考

针对当前农村土地问题的现状．认为调整农村土地关系改革土地制度是解决当前农村问题的关键之一。介绍苏格兰土地改革的经验．提出农村土地转为非农用地的交易中国家应实行限制性措施．可尝试建立“国家失地农民账户”和“国家失地农民保障基金”．从而合理分配土地交易产生的级差收益保障失地农民的合法利益。     

Moving Endpoints and the Internal Consistency of Agents' Ex Ante Forecasts

Forecasts by rational agents contain embedded initial and terminal boundary conditions. Standard time series models generate two types of long-run boundary values or steady-state 'endpoints' – fixed endpoints and moving average endpoints. Neither can explain the shifting endpoints implied by postwar movements in the cross-section of forward rate forecasts in the term structure or by post-1979 changes in survey estimates of expected long-run inflation. Multiperiod forecasts by a broader class of 'moving endpoint' time series models provide substantially improved tracking of the historical term structure and generally support the internal consistency of the ex ante long-run expectations of bond traders and survey respondents.     

Trajectories leading to school-age conduct problems.

The present study applied a semiparametric mixture model to a sample of 284 low-income boys to model developmental trajectories of overt conduct problems from ages 2 to 8. As in research on older children, 4 developmental trajectories were identified: a persistent problem trajectory, a high-level desister trajectory, a moderate-level desister trajectory, and a persistent low trajectory. Follow-up analyses indicated that initially high and low groups were differentiated in early childhood by high child fearlessness and elevated maternal depressive symptomatology. Persistent problem and high desister trajectories were differentiated by high child fearlessness and maternal rejecting parenting. The implications of the results for early intervention research are discussed, with an emphasis on the identification of at-risk parent-child dyads. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

从公共住房到租金优惠券——美国低收入阶层住房政策演化解析

本文对美国低收入阶层住房政策的演化过程作了介绍 ,分析了其中三种典型住房政策的实施效果。在把握我国国情的基础上 ,借鉴美国住房政策演化过程的经验教训 ,为建立我国弱势人群住房政策提出了建议。     

企业目标的经济学分析

市场经济条件下,股东、经理、员工、政府、社会等企业内外方方面面对企业提出了不同的要求,于是企业具有多种目标。企业是以盈利为主要目的的经济单位,因此,唯有利润才是最重要的目标,其他目标与利润目标都有着直接或间接的联系。     

基于行为经济的预期回报与创业决策关联分析

预期回报对决策具有决定性的影响。基于行为经济模型,认为创业决策依赖于预期回报和欲望水平之间的相互作用,并通过计量分析验证了预期回报对创业决策的影响。     

我国奶牛场收入政策及发展

叙述了我国目前乳业概况，就经济体制转变以来，我国的奶生产情况，牧场收入，政府所起的作用及乳业今后面临的挑战等问题进行了分析和论述。