Chl1, an ATP-Dependent DNA Helicase,Inhibits DNA:RNA Hybrids Formation at DSB Sites to Maintain Genome Stability in S. pombe

As an ATP-dependent DNA helicase, human ChlR1/DDX11 (Chl1 in yeast) can unwind both DNA:RNA and DNA:DNA substrates in vitro. Studies have demonstrated that ChlR1 plays a vital role in preserving genome stability by participating in DNA repair and sister chromatid cohesion, whereas the ways in which the biochemical features of ChlR1 function in DNA metabolism are not well understood. Here, we illustrate that Chl1 localizes to double-strand DNA break (DSB) sites and restrains DNA:RNA hybrid accumulation at these loci. Mutation of Chl1 strongly impairs DSB repair capacity by homologous recombination (HR) and nonhomologous end-joining (NHEJ) pathways, and deleting RNase H further reduces DNA repair efficiency, which indicates that the enzymatic activities of Chl1 are needed in Schizosaccharomyces pombe. In addition, we found that the Rpc37 subunit of RNA polymerase III (RNA Pol III) interacts directly with Chl1 and that deletion of Chl1 has no influence on the localization of Rpc37 at DSB site, implying the role of Rpc37 in the recruitment of Chl1 to this site.     

Research on a New Hybrid System of a Tyre Crane Using Supercapacitors

Research on a hybrid system of a crane is a focus which considers environmental protection and energy saving.A new environmental protection and energy saving hybrid system of tyre crane.which utilizes supercapacitors as the energy store device,is presented.Analyzing the pdneiple of supercapacitors,the model of the crane's hybrid system is set up in this paper,and the model of main blocks are established.Through simulation analyzing,the energy saving result of the new hybrid system is obtained,and the good application value of the new hybrid system is explained.     

Theranostic Agent Combining Fullerene Nanocrystals and Gold Nanoparticles for Photoacoustic Imaging and Photothermal Therapy

Developing photoactivatable theranostic platforms with integrated functionalities of biocompatibility, targeting, imaging contrast, and therapy is a promising approach for cancer diagnosis and therapy. Here, we report a theranostic agent based on a hybrid nanoparticle comprising fullerene nanocrystals and gold nanoparticles (FGNPs) for photoacoustic imaging and photothermal therapy. Compared to gold nanoparticles and fullerene crystals, FGNPs exhibited stronger photoacoustic signals and photothermal heating characteristics by irradiating light with an optimal wavelength. Our studies demonstrated that FGNPs could kill cancer cells due to their photothermal heating characteristics in vitro. Moreover, FGNPs that are accumulated in tumor tissue via the enhanced permeation and retention effect can visualize tumor tissue due to their photoacoustic signal in tumor xenograft model mice. The theranostic agent with FGNPs shows promise for cancer therapy.     

基于CAN总线的交流电动机在线监控系统

为了实现高可靠性现代拖动系统,文章作者提出了一种基于CAN总线技术的交流电动机在线监控系统设计方案,实现了电机远程监控与多电机群控功能,同时给出了系统结构框图、关键硬件电路原理图以及主要软件模块的程序流程图。     

电力用直流和交流一体化不间断电源设备

介绍电力用直流和交流一体化不间断电源设备的原理及应用。     

A new method for estimating initial rotor phase of self‐excited hybrid‐field synchronous motors

This paper proposes a new method for properly estimating the rotor initial phase (i.e., the position) of the newly emerging self‐excited hybrid‐field synchronous motors (SelE‐HFSMs), which have the rotor held by both a permanent magnet and a diode‐shorted held winding. The proposed method injects a spatially rotating high‐frequency voltage and detects the rotor phase directly by evaluating the norm of the associated current. The method is very simple, but has a high degree of usability. 2010 Wiley Periodicals, Inc. Electr Eng Jpn, 173(3): 49–58, 2010; Published online in Wiley InterScience ( www.interscience. wiley.com ). DOI 10.1002/eej.21027     

新型混合型限流断路器分析及试验

研究了一种基于高速斥力开关的交直流两用混合型限流断路器方案,该限流断路器在限流过程中先经过一个强迫换流过程,使得触头分离时高速斥力开关上电流减小到较小值,触头分离后再经历一个自然零电压换流过程,将斥力开关电流换流到二极管支路上.重点对限流断路器换流过程进行了理论分析及仿真,分析了其可能出现的4种分断情况.研制了400V/500A限流断路器样机,并进行了不同短路电流上升率的限流试验,验证了理论分析的正确性.     

交流电机绕组分布系数推导方法的研究

对交流电机绕组分布系数推导的代数法进行了详尽描述,并对代数法与几何法进行了比较。     

直流微电网建模与稳定性分析

针对直流微电网的稳定性问题,采用状态空间法建立了直流微电网中多种变流装置及其控制系统的平均模型,并在此基础上对直流微电网进行了小扰动稳定性分析,得出了随着变流器控制参数变化的系统特征值轨迹。分析表明,当变流器的控制系数增大到一定数值时,将会出现实部为正的系统特征值,即系统不稳定。为了验证这一分析方法的可行性,又对所研究的直流微电网进行了时域仿真,得出负荷突增时不同控制系数下的时域电压曲线。仿真结果一方面验证了稳定性分析的结果,另一方面也表明,当控制系数在稳定范围内时,系数越大,则电压控制的效果也越好。由此可见,合理选择变流器的控制参数能够很好地保证直流微电网的电压稳定性。     

变压器直流偏磁电流监测技术研究

在介绍变压器直流偏磁电流对变压器影响的基础上,对开展直流偏磁电流监测的相关技术进行了研究,并设计了一种光电型变压器直流偏磁电流监测装置,该设计在电气上完全切断了过电压及各种干扰的传播路径,能有效保证监测装置工作的稳定性、可靠性。