18万t/a中高压甲醇合成系统原始开车总结

介绍了18万t/a甲醇合成系统原始开车前的准备工作、开车过程及开车过程中触媒升温还原的注意事项,分析了原始开车过程中出现的主要问题,并介绍了相应的解决方法。     

火电厂用中水水质问题及改善措施的分析

针对火电厂用于循环冷却水和锅炉补给水的中水水质不稳定的问题,介绍通过改进污水处理阶段的工艺和深度处理必电厂初级阶段中水以提高中水水质的措施,对节能减排、保护环境吴有重要意义.     

MicroRNA-Based Diagnosis and Therapy

MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene expression. Alteration in miRNA expression results in changes in the profile of genes involving a range of biological processes, contributing to numerous human disorders. With high stability in human fluids, miRNAs in the circulation are considered as promising biomarkers for diagnosis, as well as prognosis of disease. In addition, the translation of miRNA-based therapy from a research setting to clinical application has huge potential. The aim of the current review is to: (i) discuss how miRNAs traffic intracellularly and extracellularly; (ii) emphasize the role of circulating miRNAs as attractive potential biomarkers for diagnosis and prognosis; (iii) describe how circulating microRNA can be measured, emphasizing technical problems that may influence their relative levels; (iv) highlight some of the circulating miRNA panels available for clinical use; (v) discuss how miRNAs could be utilized as novel therapeutics, and finally (v) update those miRNA-based therapeutics clinical trials that could potentially lead to a breakthrough in the treatment of different human pathologies.     

Single-Circulating Tumor Cell Whole Genome Amplification to Unravel Cancer Heterogeneity and Actionable Biomarkers

The field of single-cell analysis has advanced rapidly in the last decade and is providing new insights into the characterization of intercellular genetic heterogeneity and complexity, especially in human cancer. In this regard, analyzing single circulating tumor cells (CTCs) is becoming particularly attractive due to the easy access to CTCs from simple blood samples called “liquid biopsies”. Analysis of multiple single CTCs has the potential to allow the identification and characterization of cancer heterogeneity to guide best therapy and predict therapeutic response. However, single-CTC analysis is restricted by the low amounts of DNA in a single cell genome. Whole genome amplification (WGA) techniques have emerged as a key step, enabling single-cell downstream molecular analysis. Here, we provide an overview of recent advances in WGA and their applications in the genetic analysis of single CTCs, along with prospective views towards clinical applications. First, we focus on the technical challenges of isolating and recovering single CTCs and then explore different WGA methodologies and recent developments which have been utilized to amplify single cell genomes for further downstream analysis. Lastly, we list a portfolio of CTC studies which employ WGA and single-cell analysis for genetic heterogeneity and biomarker detection.     

神华煤燃烧性能及其在火电机组"上大压小"中的作用

在总结神华煤及与其他动力煤配煤特性的基础上,重点分析神华煤与其他动力煤不同掺烧比条件下锅炉运行的经济性能、环保性能及其他性能,突出神华煤在火电机组"上大压小"中的重要作用。     

循环流化床锅炉点火系统的数值模拟分析

循环流化床(CFB)锅炉点火系统主要以风道燃烧器为主。风道燃烧器在实际运行时,燃油着火和燃尽性能不是很理想,会出现火焰贴壁、壁面结焦等现象,因此对CFB锅炉点火系统进行数值模拟研究。针对内蒙古某电厂CFB锅炉风道燃烧器实际燃烧工况,选用非结构化有限元体积网格模型进行数值模拟。通过对点火系统的数值模拟和实测结果比较分析,验证了针对内蒙古某电厂CFB锅炉点火系统进行理论模拟所设置的物理模型和边界条件是符合实际的,理论模拟和实测结果的相对误差在10%范围内,结果较为理想。说明利用FLUENT软件对点火系统内温度场及压力场的情况进行模拟分析是可行的,对同类电厂具有一定的参考价值。     

大型煤粉锅炉炉膛传热分体式计算方法及其可视化编程

对大型煤粉锅炉炉膛分体式计算方法进行研究,把炉膛以大屏过热器低端为界分成上、下两个部分进行传热计算,并用ＶＢ为程序编制了友好的用户界面．     

UG-75/5.3-M_3型锅炉冷态流化特性的试验研究

对UG－75／5．3－M3型循环流化床锅炉在点火底料不同厚度下的料层阻力进行了测试，并获得了该型锅炉在颗粒为0～5mm时料层阻力特性曲线，进而得出了料层阻力与料层厚度关系的计算公式和临界流化风量，为该种锅炉点火时风量的控制及运行中料层厚度的调节提供了依据。     

大型立式泵机组用同步电机两个高差的安装控制

电机定转子磁场中心高差和叶轮与外壳中心高差影响机组运行,分析了影响这两个高差的因素,应保证泵机组在运行状态下这两个高差满足要求,提出了高差安装确定控制方法。     

煤层气抽采直流微网建模与稳定性分析

针对目前煤层气抽采现场用电不合理现状,构建一种新型煤层气抽采直流微网供电系统,并对该直流微网系统稳定性及控制策略进行研究。煤层气抽采直流微网供电系统分三层结构:第一层由光伏和蓄电池组成能量供给层;第二层由双向Buck/Boost变换器构成能量传输和分配层;第三层由煤层气抽采机构成负荷层。基于此架构推导了第一、二层输出阻抗Zo(s),并建立第三层煤层气抽采机电动机输入阻抗Zin(s)与受控源K??m串联的小信号模型,在此基础上得到系统全局小信号模型。考虑到呈现负阻抗特性的煤层气抽采机电动机周期性动态交变负荷引起的系统不稳定,在能量传输和分配层分析并讨论了一种基于虚拟阻抗的直流微网稳定性控制策略,以及利用下垂控制实现负荷功率动态平衡分配的方法。进一步利用阻抗匹配原则求解多项式1/(1+Zo(s)/Zin(s))主导极点,比较采取该稳定性控制策略前后的主导极点位置并分析直流微网系统稳定性。最后基于Matlab/Simulink搭建由光伏阵列、储能单元和煤层气抽采机组成的煤层气抽采直流微网系统模型,系统仿真证明了稳定性控制策略的有效性。