合理设计反馈电路以对PSM发射机进行镇噪

针对PSM发射机原有杂音补偿器在抵消杂音方面所存在的缺陷而设计了具有“静态使用、动态停用”特点的镇噪器，并详细阐述了设计思路及其优点。     

200KA铝电解槽打壳、下料气缸排风管消声装置的研究与实施

论述了噪声对人体的危害及我厂电解车间噪声的现状，分析了我厂电解车间降低噪声的必要性。并结合我厂实际情况与消声原理，研制出了一种新型的消声装置，从而达到了降低我厂电解车间噪声的目的。     

智能调频消声器的设计和实现

提出了基于无源主动噪声控制思想的一种新型消声器。该消声器采用前馈控制，利用双通道信号采集和处理系统实时处理当地有调噪声，控制器智能决策后，控制伺服电机驱动执行机构调节声波干涉频率，对低频有调噪声进行最优化干涉消声。     

《有流船用排气消声器声学性能分析》

用发展的双倒易边界元法考察了气流对双级膨胀腔消声器消声性能的影响，结果表明较高马赫数亚音速流的影响不可忽略。同时总结了内插管数量，进口位置和导流环结构对消声器传递损失的影响规律，具有一定的实用价值。     

长春-40拖拉机排气消声器改进设计

本文介绍了长春-40拖拉机排气消声器的改进设计方案,经新、旧消声器的对比实验表明,新消声器比旧消声器排气口附近噪声降低9dB(A),拖拉机环境噪声降低2dB(A),功率损失<2％,低于原消声器。     

同轴抗性消声器声学和阻力特性的数值计算与分析

使用三维数值方法计算同轴膨胀腔消声器和直通穿孔管消声器的声传递损失和流动阻力损失，详细研究了进出口管插入膨胀腔内部长度以及进出口的结构形状对消声器传递损失和阻力损失的影响。采用锥形和指数形进出口管、进出口导流环以及穿孔管均能有效地降低流动阻力损失，而对消声器的低频消声性能影响较小，但对中高频消声性能影响很大。     

内燃机排气消声器主要参数的选择（一）

根据笔者多年设计消声器的实践经验,分析影响内燃机排气消声器消声性能的各种主要参数,以及如何正确选取消声器各主要参数的方法。     

Novel Small Molecule Positive Allosteric Modulator SPAM1 Triggers the Nuclear Translocation of PAC1-R to Exert Neuroprotective Effects through Neuron-Restrictive Silencer Factor

The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) exerts effective neuroprotective activity through its specific receptor, PAC1-R. We accidentally discovered that as a positive allosteric modulator (PAM) of PAC1-R, the small-molecule PAM (SPAM1) has a hydrazide-like structure, but different binding characteristics, from hydrazide for the N-terminal extracellular domain of PAC1-R (PAC1-R-EC1). SPAM1 had a significant neuroprotective effect against oxidative stress, both in a cell model treated with hydrogen peroxide (H₂O₂) and an aging mouse model induced by D-galactose (D-gal). SPAM1 was found to block the decrease in PACAP levels in brain tissues induced by D-gal and significantly induced the nuclear translocation of PAC1-R in PAC1R-CHO cells and mouse retinal ganglion cells. Nuclear PAC1-R was subjected to fragmentation and the nuclear 35 kDa, but not the 15 kDa fragments, of PAC1-R interacted with SP1 to upregulate the expression of Huntingtin (Htt), which then exerted a neuroprotective effect by attenuating the binding availability of the neuron-restrictive silencer factor (NRSF) to the neuron-restrictive silencer element (NRSE). This resulted in an upregulation of the expression of NRSF-related neuropeptides, including PACAP, the brain-derived neurotrophic factor (BDNF), tyrosine hydroxylase (TH), and synapsin-1 (SYN1). The novel mechanism reported in this study indicates that SPAM1 has potential use as a drug, as it exerts a neuroprotective effect by regulating NRSF.     

火电厂蒸汽放空消声器及其阀门流量适配

介绍小孔消声器在电厂蒸汽放空时的消声作用、效果及其阀门流量的适配,分析ＺＦ４１６型消声器的流量－驻压特性曲线及其阀门结构的选择。