Maximum-likelihood mixture factor analysis model and its application for process monitoring

In the present paper, a mixture form of the factor analysis model is developed under the maximum-likelihood framework. In this new model structure, different noise levels of process variables have been considered. Afterward, the developed mixture factor analysis model is utilized for process monitoring. To enhance the monitoring performance, a soft combination strategy is then proposed to integrate different local monitoring results into a single monitoring chart, which is based on the Bayesian inference method. To test the modeling and monitoring performance of the proposed mixture factor analysis method, a numerical example and the Tennessee Eastman (TE) benchmark case studies are provided.     

制造企业基于Internet的设备远程诊断与维护系统研究

介绍了一个用于汽车发动机自动生产线的远程监控与诊断系统的结构与功能,对系统实现的有关关键技术进行了探讨,并给出了运行实例。     

Elevation of Tear MMP-9 Concentration as a Biomarker of Inflammation in Ocular Pathology by Antibody Microarray Immunodetection Assays

Matrix metalloproteinases are a family of enzymes fundamental in inflammatory processes. Between them, MMP-9 is up-regulated during inflammation; thus, its quantification in non-invasive fluids is a promising approach for inflammation identification. To this goal, a biomarker quantification test was developed for ocular inflammation detection using anti-MMP-9 antibody microarrays (AbMAs). After validation with eight healthy control tear samples characterized by ELISA, 20 samples were tested from individuals diagnosed with ocular inflammation due to: cataracts, glaucoma, meibomian gland dysfunction, allergy, or dry eye. Concentration values of tear MMP-9 were obtained for each sample, and 12 patients surpassed the pathological threshold (30 ng/mL). A significant elevation of MMP-9 concentration in the tears of glaucoma patients compared with healthy controls was observed. In order to evaluate the diagnostic ability, an ROC curve analysis was performed using our data, determining the optimal threshold for the test at 33.6 ng/mL of tear MMP-9. In addition, a confusion matrix was applied, estimating sensitivity at 60%, specificity at 88%, and accuracy at 68%. In conclusion, we demonstrated that the AbMAs system allows the quantification of MMP-9 in pathologies that involve inflammation of the ocular surface.     

基于Modbus现场总线的综采工作面大型设备监测监控系统

简要介绍了Modbus通讯协议,重点阐述了综采工作面大型设备实现远程监测监控功能的软硬件技术方案。在HT6L1-400Z/1140智能型组合电器的基础上采用Modbus现场总线,编制了通讯程序,实现了综采工作面大型设备的远程监测监控。     

采煤机位置监测装置的原理与应用

介绍了采煤机位置监测装置的主要功能、组成、工作原理以及应用。     

分布式监测诊断系统总体设计思想的研究

研究了分布式监测诊断系统的基本理论框架,提出了分布式监测诊断系统的定义、层次结构和各层的功能定义,并分析了分布式监测诊断系统与生产控制系统的关系。     

Development and Use of a Kinetical and Real-Time Monitoring System to Analyze the Replication of Hepatitis C Virus

In microbiological research, it is important to understand the time course of each step in a pathogen’s lifecycle and changes in the host cell environment induced by infection. This study is the first to develop a real-time monitoring system that kinetically detects luminescence reporter activity over time without sampling cells or culture supernatants for analyzing the virus replication. Subgenomic replicon experiments with hepatitis C virus (HCV) showed that transient translation and genome replication can be detected separately, with the first peak of translation observed at 3–4 h and replication beginning around 20 h after viral RNA introduction into cells. From the bioluminescence data set measured every 30 min (48 measurements per day), the initial rates of translation and replication were calculated, and their capacity levels were expressed as the sums of the measured signals in each process, which correspond to the areas on the kinetics graphs. The comparison of various HuH-7-derived cell lines showed that the bioluminescence profile differs among cell lines, suggesting that both translation and replication capacities potentially influence differences in HCV susceptibility. The effects of RNA mutations within the 5′ UTR of the replicon on viral translation and replication were further analyzed in the system developed, confirming that mutations to the miR-122 binding sites primarily reduce replication activity rather than translation. The newly developed real-time monitoring system should be applied to the studies of various viruses and contribute to the analysis of transitions and progression of each process of their life cycle.     

高速轧机润滑油品含水率实时检测系统的设计与应用

本文简要介绍了高速轧机润滑油品含水率实时检测系统的设计内容与应用情况,本系统使用效果明显,在国内本专业领域处于领先地位。     

电容器故障监测系统的应用研究

基于近年并联电容器装置频繁出现故障的现象和特点,研制出一套电容器故障监测系统,分别提取并联电容器装置的电流和电压实时信号,利用Labview虚拟仪器程序进行软件开发实现在线监测,对获取的电流电压信号进行谐波、合闸涌流、暂态过电压等方面进行分析和研究,并应用于现场测量,给出了一起电容器内部击穿故障的监测实例。     

IFIX在卷烟厂自动化生产物流监控系统中的应用

介绍了iFIX工控组态软件在卷烟厂的自动化生产物流监控系统中的应用。详细论述了生产物流监控系统的结构、组态过程、软硬件配置及软件设计等。可见iFIX在大型复杂生产物流分布式控制系统中的应用是可行的,保障了生产过程的连续运行,同时降低了生产制造成本。