某铜矿主矿体采矿方法优化选择研究

针对某铜矿主矿体500 m水平西区域复杂难采矿体,提出了进路式上向分层充填采矿法、脉内凿岩出矿巷低分段空场小步距回采嗣后充填法及脉外凿岩出矿巷低分段空场小步距回采嗣后充填法三种可行开采方案,并对三种采矿方案的采场布置、采切工程、回采工艺等进行了详细的介绍。对比分析三种采矿方法的优缺点和技术经济指标,优选出进路式上向水平分层充填采矿法进行开采。该采矿方法回采过程中采用浅孔爆破,能较好地保护上盘不稳定含砂层,工人作业环境安全性高,且其采切比、贫化损失相对较低,出矿品位较高,综合效益明显。     

液压机本体柔性化设计相关技术的研究

针对液压机本体设计特点，在液压机本体CAD应用系统的开发中，引入了柔性化设计的概念，以Pro／E为建模后台、VB6．0为操作语言，研究了柔性化设计的相关技术，并提出了相关解决方案，并为以：Pro／E为后台的应用系统的开发提供了一种可行方案。     

倾斜冷却体法制备半固态浆料的研究现状

介绍了低成本、高效率的倾斜冷却体法制备半固态浆料的方法，综述了国内外对该方法的研究现状、相关工艺参数对组织形貌的影响及需要解决的关键问题。     

轿车铝合金油泵壳体液态挤压工艺

采用液态挤压代替压力铸造及热模锻生产轿车铝合金油泵壳体,不仅克服了压铸件内部容易形成气孔和氧化夹杂的缺陷,而且减少了热模锻的投资及提高了材料利用率。本文介绍了铝合金油泵壳体液态挤压的模具结构及设计参数、技术经济分析。     

重组人EC-SOD包涵体的稀释复性及重折叠后蛋白的纯化

目的确定重组人ECSOD包涵体体外稀释复性和复性后蛋白纯化的适宜方法。方法通过对pH、温度、包涵体蛋白浓度、尿素和精氨酸浓度及氧化还原对比率的定性定量分析,研究重组人ECSOD包涵体体外稀释复性的基本条件。采用金属离子亲和柱(IMAC)和肝素亲和柱(Heparinsepharose)对复性蛋白进行纯化,比较纯化效率的差异。结果最佳复性条件为pH8.5,尿素浓度为1.5molL,精氨酸浓度大于0.3molL,GSH∶GSSG=4∶1;复性温度及包涵体蛋白终浓度越高,复性效率越低。IMAC和Heparinsepharose亲和柱均可用来纯化复性蛋白溶液,但Heparinsepharose纯化效率较高。结论确定了重组人ECSOD包涵体体外稀释复性的最佳条件及复性后蛋白纯化的方法。     

Theoretical Models for Binder Burnout

The kinetics of binder burnout, from a ceramic green body, are considered for the case of an "unzipping" binder which decomposes to produce a volatile monomer. The process is considered to fail if the concentration of monomer in the green body exceeds that in equilibrium with vapor at 1 atm (≅10⁵ Pa), when an internal bubble would be expected to form. Steady-state diffusional calculations and computer simulations explore the size and temperature dependence of the process and are in agreement. The model suggests that it is not feasible to burn out a large flat piece greater than about 3 mm thick, without going to very long times of burnout. The kinetics are significantly improved if porosity develops in the piece during the early stages of decomposition, as opposed to the retreat of the binder into the piece on a uniform front.     

Studies on high-performance blended/multiblended cements and their durability characteristics

Number of blends were prepared by intergrinding clinker, gypsum, fly ash, calcined clay, microsilica and limestone in laboratory ball mill in varying percentages, and their physical properties such as fineness, consistency, setting time and compressive strength have been determined. The durability tests on selected compositions were also conducted by exposing the mortar cubes separately in 5% Na₂SO₄ and 5% NaCl solutions till the age of 90 and 180 days. The performance was observed by compressive strength development criteria after various length of exposure. Results have been discussed and found that the durability of blended cement is higher than the ordinary Portland cement.     

重组人白细胞介素-10在大肠杆菌中的表达及生物学活性分析

目的在大肠杆菌中表达重组人白细胞介素-10(Interleukin-10,IL-10),并检测其生物学活性。方法将IL-10基因重组到质粒pET11c中,转化BL21(DE),提取质粒,经酶切鉴定和测序分析;在25℃用低浓度的IPTG诱导表达,对包涵体IL-10稀释复性;经ELISA检测其含量,MC/9细胞增殖法检测其生物学活性。结果工程菌IL-10/pET11c/BL21诱导表达的目的蛋白以可溶性和包涵体两种形式存在,Westernblot鉴定证实为IL-10蛋白,两种形式的IL-10均具有一定的生物学活性。结论已成功地在大肠杆菌中表达了IL-10,为进一步纯化和制备IL-10的基因工程药物打下了基础。     

50年来辽宁省不同等级舒适日数演变及空间区划分析

根据1964—2015年辽宁省23个气象站点的逐日平均气温、相对湿度及平均风速资料,采用人体舒适度指数法计算人体舒适度指数,在季尺度上分析辽宁省不同等级舒适日数演变情况及典型旅游城市最佳旅游期;运用旋转经验正交函数分解法(REOF),分析人体舒适度指数季尺度空间变化特征,并应用ArcGIS软件进行舒适区域划分。结果表明:①辽宁省多年平均冷不舒适日数呈降低趋势,舒适日数呈增加趋势,热不舒适日数也呈微弱增加趋势;舒适程度夏季＞秋季＞春季＞冬季;②除冬季外5座典型旅游城市均适宜旅游,夏季为最佳旅游期;其中,沈阳、本溪更适宜春季旅游,大连更适宜秋季旅游。③辽宁省四季舒适度变化情况可大致划分为辽西、辽中、辽东三个区域,具体划分情况随季节有相应变化,总体舒适度由辽宁东部向西部逐渐递减。     

The ageing Australian firefighter: an argument for age-based recruitment and fitness standards for urban fire services

Currently, there is no enforcement of physical standards within Australian fire services post-recruitment, possibly leading to inappropriate fitness and body composition. This study evaluated the impacts of ageing on physical standards of Australian firefighters. Seventy-three firefighters from three different 10-year age groups [25–34 years (n = 27), 35–44 years (n = 27), 45–54 years (n = 19)] volunteered for physical testing using dual-energy X-ray analysis and existing fitness tests used for recruitment by an Australian fire service. Older (45–54 years) participants demonstrated significantly poorer physical standards compared with younger participants including cardiovascular fitness (p < 0.05), strength (p = 0.001) and simulated operational power testing tasks (p < 0.001). Age-related body composition changes were also observed independent of body mass index. Minimum recruitment standards and fitness programs need to account for age-related declines in physical capabilities to ensure that the minimum standard is maintained regardless of age.

Practitioner Summary: Using dual-energy X-ray analysis and established fitness testing protocols, this study aimed to gain an appreciation of the current standards of body composition and fitness of Australian firefighters and the effects of ageing on their physical abilities post-recruitment. The study demonstrated a significant decline in physical standards due to age.