A Generalized System for Photo-Responsive Membrane Rupture in Polymersomes

Polymersomes are vesicles whose membranes are comprised of self-assembled block co-polymers. We recently showed that co-encapsulating conjugated multi-porphyrin dyes in a polymersome membrane with ferritin protein in the aqueous lumen confers photo-lability to the polymersome. In the present study, we illustrate that the photo-lability can be extended to vesicles containing dextran, an inert and inexpensive polysaccharide, as the luminal solute. Here we explore how structural features of the polymersome/porphyrin/dextran composite affect its photo-response. Increasing dextran molecular weight, decreasing block copolymer molecular weight, and altering fluorophore-membrane interactions results in increasing the photo-responsiveness of the polymersomes. Amphiphilic interactions of the luminal encapsulant with the membrane coupled with localized heat production in the hydrophobic bilayer likely cause differential thermal expansion in the membrane and the subsequent membrane rupture. This study suggests a general approach to impart photo-responsiveness to any biomimetic vesicle system without chemical modification, as well as a simple, bio-inert method for constructing photo-sensitive carriers for controlled release of encapsulants.     

采用光激励和光检测的LED电特性测试方法

针对目前用于测试LED光电特性多采用接触式的电注入检测方法存在系统复杂、成本高、检测效率低且易造成芯片损伤等不足,提出一种采用光激励和光检测的非接触式检测方法。通过获取光激励LED p-n结产生的光致发光（PL）光谱,在建立了LED PL、电致发光（EL）效应间的确切联系以及LED发光光谱特性与其电特性间的对应关系的基...     

从专利角度看LED显示技术的发展

LED显示技术作为现代信息社会的重要标志之一,已经被广泛应用于多个行业中.从专利信息分析的角度,从LED显示技术历年专利申请量、重要申请人、IPC分类情况以及国内重要企业技术构成进行了分析,探讨了LED显示技术的发展过程,介绍了LED显示技术的行业的发展现状,为相关企业明晰行业动态,实现知识产权战略布局提供了有效依据.     

A Resistant Quantum Key Exchange Protocol and Its Corresponding Encryption Scheme

The emergence of quantum computer will threaten the security of existing public-key cryptosystems, including the Diffie Hellman key exchange protocol, encryption scheme and etc, and it makes the study of resistant quantum cryptography very urgent. This motivate us to design a new key exchange protocol and eneryption scheme in this paper. Firstly, some acknowledged mathematical problems was introduced, such as ergodic matrix problem and tensor decomposition problem, the two problems have been proved to NPC hard. From the computational complexity prospective, NPC problems have been considered that there is no polynomial-time quantum algorithm to solve them. From the algebraic structures prospective, non-commutative cryptography has been considered to resist quantum. The matrix and tensor operator we adopted also satisfied with this non-commutative algebraic structures, so they can be used as candidate problems for resisting quantum from perspective of computational complexity theory and algebraic structures. Secondly, a new problem was constructed based on the introduced problems in this paper, then a key exchange protocol and a public key encryption scheme were proposed based on it. Finally the security analysis, efficiency, recommended parameters, performance evaluation and etc. were also been given. The two schemes has the following characteristics, provable security,security bits can be scalable, to achieve high efficiency, quantum resistance, and etc.     

LPP聚酰亚胺取向膜的制备及其取向研究

合成具有光敏性的聚酰亚胺OPDA－BAPAF－Cin－CN,对其化学性质进行研究。用这种聚酰亚胺作为光致取向剂,能对液晶MLC－LC2000有良好的取向效果。研究了这种取向剂对液晶MLC－LC2000的取向方向及提高预倾角的作用,发现该取向剂有良好的热稳定性。     

电子束曝光UV3正性抗蚀剂的工艺研究

为了在体硅CMOSFinFET中用等离子体腐蚀精细凹槽图形，研究了将电子束直写曝光用于原为深紫外光学曝光的UV3正性抗蚀剂的工艺技术；详细分析了包括膜厚、曝光能量、曝光剂量、显影时间、设计尺寸和衬底材料等在内的各类工艺参数与实际曝光图形效果的关系；特别指出了曝光过程中特有的延迟效应及解决办法。采用最终的优化工艺条件，得到了合适的图形效果。     

基于SU-8胶转子的非接触压电微马达

研制了一种非接触压电微马达，通过阻抗分析仪对定子进行扫频测试，确定其共振频率，并且详细介绍了SU-8胶转子制作的工艺流程。利用转速仪比较不同形状和尺寸的转子在调频和调压下的转速，从而确立压电微马达的最优转子。转子半径为6mm，叶片宽度为6mm的三叶片转子转速最高为3569r／min。转子的启动电压和最高电压分别为8V和24V。     

多光子J-C模型的研究

本文推广二能级原子J-C模型到多光子过程。求得在存在偏调情况下,单模相干场对二能级原子激发时的光子数几率分布函数,由此研究了原子受激辐射性质。     

手绘人脸识别的研究

人脸自动识别技术的应用领域十分广泛,其中从警察局的犯罪嫌疑人数据库中进行人脸图像的自动识别就是人脸识别的实际应用之一。但是,在许多情况下,犯罪嫌疑人的照片或图像是不容易得到的,最好的代替方法就是一张通过目击者的回忆而得到的手绘草图。介绍一种在人脸草图和照片之间进行自动识别的方法。通过将一张照片图像转化成手绘草图,减小了在照片和草图之间的差别,这样就为照片和图像进行匹配提供了有效的条件。在包含188个人脸图像数据中进行试验充分地证明了该算法的有效性。     

Nanometric Micelles with Photo‐Triggered Cytotoxicity

The development of a photo‐responsive micellar system capable of triggering cell death is reported. Precursors of the micelles are synthesized by connecting a lipophilic chain to a hydrophilic polyethylene glycol via a photo‐labile nitrobenzyl group. The resulting amphiphilic units are self‐assembled in water forming 12 nm micelles that are readily internalized into cells. Upon photo‐irradiation, micelles undergo cleavage and yield a cytotoxic nitrosobenzaldehyde derivative, which significantly inhibits the proliferation of MDA‐MB‐231 cells under standard in vitro conditions.