涡流检测对比试样的作用

阐述了涡流检测对比试样的作用,通过对比试验说明了试样中两种类型的人工缺陷（通孔和槽形）的优缺点和槽形人工缺陷相位信号与钢管制造过程中容易产生的表面缺陷信号更相似。在普遍采用通孔的情况下,建议在试样上加工槽形人工缺陷与通孔进行对比以提高检测质量。     

Dual Knockdown of Musashi RNA-Binding Proteins MSI-1 and MSI-2 Attenuates Putative Cancer Stem Cell Characteristics and Therapy Resistance in Ovarian Cancer Cells

In ovarian cancer, therapy resistance mechanisms complicate cancer cell eradication. Targeting Musashi RNA-binding proteins (MSI) may increase therapeutic efficacy. Database analyses were performed to identify gene expression associations between MSI proteins and key therapy resistance and cancer stem cell (CSC) genes. Then, ovarian cancer cells were subjected to siRNA-based dual knockdown of MSI-1 and MSI-2. CSC and cell cycle gene expression was investigated using quantitative polymerase chain reaction (qPCR), western blots, and flow cytometry. Metabolic activity and chemoresistance were assessed by MTT assay. Clonogenic assays were used to quantify cell survival post-irradiation. Database analyses demonstrated positive associations between MSI proteins and putative CSC markers NOTCH, MYC, and ALDH4A1 and negative associations with NOTCH inhibitor NUMB. MSI-2 expression was negatively associated with the apoptosis regulator p21. MSI-1 and MSI-2 were positively correlated, informing subsequent dual knockdown experiments. After MSI silencing, CSC genes were downregulated, while cell cycle progression was reduced. Metabolic activity was decreased in some cancer cells. Both chemo- and radioresistance were reduced after dual knockdown, suggesting therapeutic potential. Dual knockdown of MSI proteins is a promising venue to impede tumor growth and sensitize ovarian cancer cells to irradiation and chemotherapy.     

大壁厚高钢级管线钢DWTT断口分析

对不同缺口形式和不同厚度的大壁厚高钢级管线钢试样进行了落锤撕裂试验,并对断口形貌进行了研究。结果表明:API RP 5L3对无效试样的定义已经不适用于大壁厚高钢级管线钢;大壁厚高钢级管线钢的DWTT压制缺口试样出现异常断口的几率较大。建议在试验时尽量采用人字形缺口的全壁厚试样;对于大壁厚高钢级管线钢,不管何种缺口形式的落锤撕裂试样,其断口都容易出现分离现象。     

TRANSIENT THERMOELASTIC CONTACT PROBLEM IN A LONG,CIRCULAR CYLINDER

This paper treats a transient thermoelastic contact problem in a long, circular cylinder to which a heated rigid band is bonded. The problem may be reduced to that of solving dual-integral equations. The radial, hoop, and axial stresses have singularities at the end of rigid band on the cylindrical surface. The coefficients which may determine the strength of singularities of stresses are introduced.     

高填方下加筋土高挡墙实测变形分析

为了揭示位于“V”形沟谷中的某座3级加筋土挡墙的变形规律,在现场实测数据的基础上,重点分析了高填方下3级加筋土高挡墙墙面板位移、墙后填土体沉降、高填方下路面沉降以及挡墙下涵洞底部沉降在施工期间和竣工后的变化情况。结果表明:①加筋土挡墙墙面板的水平位移、竖向位移以及墙后填土体的沉降主要发生在施工期间,且数值都比较大,竣工后1~2 a的时间内,其变形趋于稳定,但总的累积变形较大,说明加筋土挡墙能够适应较大变形的填方工程,这是其优势所在;②在“V”形沟谷中采用高填方下加筋土高挡墙的结构形式能满足路面沉降要求,高填方下的涵洞也是安全的;③由于挡墙筋带的特殊性,使得形成的加筋土挡墙具有锚定板挡墙和土钉墙的某些优点,既能约束墙内土体的变形,又能作为整体很好地同周围“V”形沟谷变形相协调,使得填方内应力重分布,路面沉降变形平缓过渡,未产生明显差异沉降,使用效果良好。这种挡墙结构在山区公路铁路建设中具有广阔的应用前景,值得推广。     

基于自适应陷波器的噪声调频干扰抑制方法

针对线性调频引信抗噪声干扰能力比较差的问题,提出了基于自适应陷波器的噪声调频干扰抑制方法。该方法根据线性调频引信差频信号的单频特性,将自适应陷波器应用到线性调频引信中,对噪声调频干扰进行抑制。通过自适应调整陷波器的权值,使陷波器在差频信号的频率点具有陷波特性,从而达到噪声调频干扰抑制的目的。仿真结果表明：SJB=-10 dB时,仍然能达到很好的噪声调频干扰抑制效果。     

Time-varying AR modeling and adaptive IIR notch filter for anti-jamming DSSS receiver

Using Time-Varying AR (TVAR) model and adaptive notch filter is a new method for the non-stationary jammer suppression in Direct Sequence Spread Spectrum (DSSS). The performance of TVAR model for Instantaneous Frequency (IF) estimation will be affected by some factors such as basis functions. Focusing on this problem, the optimal basis function of TVAR model for the IF estimation of the LFM signal is obtained in this paper. Besides the depth and width of notching, the phase properties of notch filter affect the Signal-to-Interference plus-Noise Ratio (SINR) of correlation output to the narrowband jammer suppression in DSSS, in response to the problem the closed solution of correlation output SINR improvement has been derived when a single frequency jammer passes through direct IIR notch filter, and its performance has been compared with those of five coefficient FIR filters. Later, a novel method for LFM jammer suppression based on Fourier basis TVAR model and direct IIR notch filter is proposed. The simulation results show the effectiveness of the proposed method.     

一种中心频率和品质因子可调的全集成陷波器

介绍了一种新颖的全集成50/60Hz陷波器。该陷波器采用电流舵技术,克服了常规陷波器难以集成、线性失真大的缺点,并且中心频率和品质因子可分别通过偏置电压和编程调节。电路在SMIC 0.18μm CMOS工艺上设计并流片。测试结果表明中心频率调节范围为0.6 Hz~252Hz,品质因子可设为1、2、5或者10,总谐波失真仅有-76dB,远低于其他文献。最后,采用本陷波器对ECG信号进行了实时滤波,结果证明本电路可行。     

心脏病与高频心电研究

寻求心脏病的早期诊断方法是当务之急,高频心电除了具有较宽的通频带和较小信号幅度外,它比常规心电图具有更多的有关心脏活动状态的信息,可以观察到更多有关心脏主要部位病变的细节,能揭示出QRS综合波上某些部位的波形特征,所谓切迹(motch)和转折(slur)。本文重点研究高频心电的分析和识别方法及其技术实现。     

Modified Notch Filter-based Instantaneous Phasor Estimation for High-speed Distance Protection

A novel method for estimating the instantaneous phasor of a fault current signal is proposed for high-speed distance protection immune to a DC-offset. The method uses a modified notch filter in order to eliminate the fundamental frequency component from the fault current signal. Since the output of the modified notch filter is the delayed DC-offset, delay compensation results in the same waveform as the original DC-offset. Subtracting the obtained DC-offset from the fault current signal yields a sinusoidal waveform, which becomes the real part of the instantaneous phasor. The imaginary part of the instantaneous phasor is based on the first difference of the fault current signal. Since a DC-offset also appears in the first difference, the DC-offset is removed from the first difference using the results of the delay compensation. The performance of the proposed method was evaluated for a–phase to ground faults on a 345 kV 100 km overhead transmission line. The Electromagnetic Transient Program was used to generate fault current signals for different fault locations and fault inception angles. The performance evaluation showed that the proposed method can estimate the instantaneous phasor of a fault current signal with high speed and high accuracy. The paper concludes by describing the hardware implementation of the proposed method on a prototype unit based on a digital signal processor.