融合交通态势修正的台风灾害后多维度智能调拨策略

针对台风灾害后交通信息不确定、调拨策略考虑维度不足等问题,提出融合交通态势修正的台风灾害后多维度智能调拨策略。采用历史交通态势数据拟合道路通行时间概率分布,并基于拉丁超立方采样对交通态势进行随机抽样,以计算更准确的道路通行时间。考虑交通、电网、用户等多维度,以抢修队伍、抢修物资、应急发电车等作为调拨主体进行台风灾害后抢修调拨,提出考虑调拨距离、恢复时间、失负荷量最优的多维智能调拨策略,利用模糊隶属度函数求取帕累托前沿最优调拨方案。根据2018年台风“山竹”下的珠海市数据验证调拨策略的有效性。算例结果表明所提多维度智能调拨策略能有效缩短台风灾害后恢复进程,提升电网防灾减灾能力。     

润湿剂种类对热烧结锌铝涂层性能的影响

用6种不同类型的润湿剂制备涂层。采用SEM方法分析了涂层的表面微观形貌,通过胶带试验、盐雾试验、自腐蚀电位-时间曲线、阳极极化曲线等方法研究所制备涂层的结合力、耐蚀性和电化学性能,筛选出的3种聚合多元醇类润湿剂涂层性能良好。润湿剂是影响涂层结合力的重要因素,对涂层的耐盐雾腐蚀性能和电化学性能均有影响。     

引入智能虚拟讲解员的云展厅构建与交互反馈研究

奥林匹克遗产是全人类的宝贵财富,利用科技与文化艺术相融合,对实现北京冬奥会及奥林匹克遗产和精神文化的多元呈现和高效传播至关重要.线上云展厅作为信息时代数字博物馆发展的重要趋势,虽然在单项数字博物馆与交互系统技术研究方面已具备较好的基础,但尚未形成体系化、智能化、交互友好的冬奥会奥林匹克数字博物馆系统.面向北京2022年冬季奥林匹克运动会,提出一种具有交互反馈的云展厅系统构建方式,通过构建具有虚拟讲解员的智能交互云展厅,进一步探索交互反馈在知识传播型的数字博物馆中对于非物质文化遗产的传播作用.为了探索视听交互反馈对云展厅的奥林匹克精神文化传播的影响,同时提升知识传播型云展厅中的用户体验,对32名参与者进行用户实验.研究结果表明,所构建的云展厅能够极大地促进奥林匹克文化与精神的传播;同时,在云展厅中引入视听交互反馈能够提高用户的感知控制,从而有效地提升用户体验.     

敷设声学覆盖层的板架结构抗冲击性能数值计算研究

为提高潜艇的隐身性能,通常在潜艇非耐压壳板外表面敷设消声瓦,在耐压壳体的外表面敷设隔声去耦瓦,在耐压壳体内表面敷设"阻尼层"(以上三种结构统称为多种声学覆盖层);由于声学覆盖层含有空腔的特殊结构形式,该空腔结构形式在受到爆炸冲击波时,腔体将产生变形并吸收能量,这将严重影响潜艇的抗冲击性能。因此,针对敷设声学覆盖层的板架结构的吸能性能进行研究,找出了覆盖层空腔结构变形、速度及加速度与冲击波能量吸收之间的关系,得到敷设声学覆盖层板架结构的抗冲性能;并对声学覆盖层结构进行优化,在此基础上,给出兼具抗冲和隔振功能的声学覆盖层结构设计及性能参数的优化建议。     

PE泡沫塑料抗静电性能研究

主要研究用十八烷基二甲基羟乙基季铵硝酸盐和硬脂酸单甘油酯混合物型抗静电剂,采用浸渍法来改善聚乙烯(PE)泡沫塑料的抗静电性能,以及抗静电剂对PE泡沫塑料其它性能的影响,并探讨加入固色剂以延长泡沫塑料的抗静电时间。     

润滑剂TAF在改性工程塑料中的应用

介绍润滑剂改性乙撑双脂肪酸酰胺(TAF)的独特结构及其与聚合物良好的相容性,以及它在聚合物中良好的分散性,并以实际应用效果表明,TAF对改善玻纤增强工程塑料的玻纤外露具有十分明显的效果,从而改善了玻纤增强工程塑料的表面粗糙度。     

Using ELP Repeats as a Scaffold for De Novo Construction of Gadolinium-Binding Domains within Multifunctional Recombinant Proteins for Targeted Delivery of Gadolinium to Tumour Cells

Three artificial proteins that bind the gadolinium ion (Gd³⁺) with tumour-specific ligands were de novo engineered and tested as candidate drugs for binary radiotherapy (BRT) and contrast agents for magnetic resonance imaging (MRI). Gd³⁺-binding modules were derived from calmodulin. They were joined with elastin-like polypeptide (ELP) repeats from human elastin to form the four-centre Gd³⁺-binding domain (4MBS-domain) that further was combined with F3 peptide (a ligand of nucleolin, a tumour marker) to form the F3-W4 block. The F3-W4 block was taken alone (E2-13W4 protein), as two repeats (E1-W8) and as three repeats (E1-W12). Each protein was supplemented with three copies of the RGD motif (a ligand of integrin αvβ3) and green fluorescent protein (GFP). In contrast to Magnevist (a Gd-containing contrast agent), the proteins exhibited three to four times higher accumulation in U87MG glioma and A375 melanoma cell lines than in normal fibroblasts. The proteins remained for >24 h in tumours induced by Ca755 adenocarcinoma in C57BL/6 mice. They exhibited stability towards blood proteases and only accumulated in the liver and kidney. The technological advantages of using the engineered proteins as a basis for developing efficient and non-toxic agents for early diagnosis of tumours by MRI as well as part of BRT were demonstrated.     

Molecular Contrast Optical Coherence Tomography and Its Applications in Medicine

The growing need to understand the molecular mechanisms of diseases has prompted the revolution in molecular imaging techniques along with nanomedicine development. Conventional optical coherence tomography (OCT) is a low-cost in vivo imaging modality that provides unique high spatial and temporal resolution anatomic images but little molecular information. However, given the widespread adoption of OCT in research and clinical practice, its robust molecular imaging extensions are strongly desired to combine with anatomical images. A range of relevant approaches has been reported already. In this article, we review the recent advances of molecular contrast OCT imaging techniques, the corresponding contrast agents, especially the nanoparticle-based ones, and their applications. We also summarize the properties, design criteria, merit, and demerit of those contrast agents. In the end, the prospects and challenges for further research and development in this field are outlined.     

CE/纳米SiO2复合材料的改性研究

利用纳米SiO2对氰酸酯树脂(CE)进行改性。结果表明,适量的纳米SiO2可提高CE/纳米SiO2复合材料的冲击强度和弯曲强度;选用不同分子尺寸的偶联剂KH-560和SCA-3对纳米SiO2进行表面处理,扫描电镜(SEM)表明,纳米SiO2经偶联剂处理后CE/纳米SiO2复合材料的静态力学性能、动态力学性能都得到了不同程度的提高,特别是经SCA-3处理后的效果更加明显,偶联剂的加入改善了纳米SiO2在CE中的分散状态,使纳米SiO2与CE之间的界面结合强度进一步提高。     

增韧尼龙滑轮专用料的研制及应用

采用双螺杆挤出加工工艺,通过添加不同组分制得增强增韧尼龙材料,比较了尼龙品种、增韧剂、玻璃纤维及助剂对材料的改性效果,并分析了生产工艺对材料性能的影响,据此确定了材料的最佳工艺参数和配方,并成功应用在割草机滑轮制品上。