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This review reports recent advances in the application of bacterial nanocellulose (BNC) in biomedical fields. BNC has attracted both academic and industrial attention as it shows interesting properties for both biomedical and cosmetic applications. Herein, the structure, properties and selected applications of BNC in the preparation of wound dressings and artificial skin are discussed in general, and detailed examples are also drawn from the scientific literature. In this review the most common applications are presented in detail together with issues related to regenerative medicine and biomedicine, skin tissue engineering, auricular cartilage reconstruction, bone regeneration and the treatment of traumatic tympanic membrane perforation. © 2019 Society of Chemical Industry 相似文献
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Lanthanide‐doped nanomaterials have attracted significant attention for their preeminent properties and widespread applications. Due to the unique characteristic, the lanthanide‐doped photoluminescence materials with hollow structures may provide advantages including enhanced light harvesting, intensified electric field density, improved luminescent property, and larger drug loading capacity. Herein, the synthesis, properties, and applications of lanthanide‐doped photoluminescence hollow structures (LPHSs) are comprehensively reviewed. First, different strategies for the engineered synthesis of LPHSs are described in detail, which contain hard, soft, self‐templating methods and other techniques. Thereafter, the relationship between their structure features and photoluminescence properties is discussed. Then, niche applications including biomedicines, bioimaging, therapy, and energy storage/conversion are focused on and superiorities of LPHSs for these applications are particularly highlighted. Finally, keen insights into the challenges and personal prospects for the future development of the LPHSs are provided. 相似文献
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Chor Yong Tay Magdiel Inggrid Setyawati Jianping Xie Wolfgang J. Parak David Tai Leong 《Advanced functional materials》2014,24(38):5936-5955
In nanomedicine design, emphasis is centered on the engineered impacts of the nanomaterials (NMs). However, failure to understand the unintended effects of nanomaterials on the cell biology can affect the overall performance, approval, and adoption in the clinic. Much of these unintended effects arise from unique physico‐chemical properties of the NMs. This feature article discusses some of the key physico‐chemical parameters of NMs and highlights how they could cause unexpected and novel biological responses, with some insights into their underlying mechanisms. 相似文献
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学术期刊中的附加数据是进行数据分析和文本挖掘的重要依据,具有的分散性、多样性和时效性的特点,难以管理和维护,文章将这类数据称HotData。HotDataSpider以生物医学类文献为研究对象,对生物信息学领域15本国际权威期刊提供的附加数据进行分析,实现了自动抽取、转换,最终将整理好的数据集批量导入到上海生物信息技术研究中心提供的HotData主题数据库中。 相似文献
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Ivana Jarak Inês Silva Ctia Domingues Ana Isabel Santos Francisco Veiga Ana Figueiras 《International journal of molecular sciences》2022,23(15)
The fast advancement in nanotechnology has prompted the improvement of numerous methods for the creation of various nanoscale composites of which nanofibers have gotten extensive consideration. Nanofibers are polymeric/composite fibers which have a nanoscale diameter. They vary in porous structure and have an extensive area. Material choice is of crucial importance for the assembly of nanofibers and their function as efficient drug and biomedicine carriers. A broad scope of active pharmaceutical ingredients can be incorporated within the nanofibers or bound to their surface. The ability to deliver small molecular drugs such as antibiotics or anticancer medications, proteins, peptides, cells, DNA and RNAs has led to the biomedical application in disease therapy and tissue engineering. Although nanofibers have shown incredible potential for drug and biomedicine applications, there are still difficulties which should be resolved before they can be utilized in clinical practice. This review intends to give an outline of the recent advances in nanofibers, contemplating the preparation methods, the therapeutic loading and release and the various therapeutic applications. 相似文献
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综述了纳米管状埃洛石在医学与生物医学、纳米复合材料和环境污染治理等领域的应用研究进展。重点评述了埃洛石在上述领域的研究现状、面临挑战和未来前景。埃洛石由于自身独特的纳米管状结构和好的生物相容性,可用于药物、生物活性分子、化妆品、除草剂、抗氧化剂、抗腐蚀剂和阻燃剂等的储存和可控释放,在药物输送、抗微生物材料、自修复聚合物以及再生医学等领域具有广阔的应用前景,是我国具有资源优势的一种重要非金属矿资源。埃洛石在人体内的相容性和细胞毒性以及埃洛石作为药物或生物活性分子(如小干扰RNA)载体等研究是今后需大力关注和投入的研究方向。 相似文献
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