二丙基硅烷双酚A环氧树脂的表征及固化性能研究

采用红外光谱（FT—IR）和核磁共振（^29Si NMR）对3,3’-二（3-三甲氧基硅丙基）双酚A环氧树脂（SEP）进行了结构表征,并对其性能和固化进行了研究。该树脂为含烷氧硅基的环氧树脂,室温下可流动,室温下黏度比E51大,在60℃以上黏度相近。采用表干时间、DSC和FT-IR等对SEP的湿固化研究结果表明,该环氧树脂通过硅氧烷水解缩合而固化,表干时间随固化温度升高而减小。该环氧树脂可以像E-51一样用胺类固化剂进行固化,低温下凝胶时间稍长,90％以上比较接近。     

铽-对氨基苯甲酸的原位合成和光固化荧光防伪油墨的性能

在EA基质中,合成了铽-对氨基苯甲酸配合物荧光剂,红外光谱的分析表明,配合物的吸收峰被EA(EA为双酚A-环氧丙烯酸酯)基质掩盖,表现为EA的特征吸收;荧光激发光谱、荧光发射光谱的研究表明,在EA基质中铽-对氨基苯甲酸配合物已经形成,并且表现出强的铽离子的特征荧光,即发出强的绿色荧光。由此荧光剂制备的光固化荧光防伪油墨在紫外光照射下能发出强的绿色荧光,经固化后的荧光强度明显低于固化前的荧光强度,并讨论了荧光猝灭机理。     

Bisphenol S Impairs Invasion and Proliferation of Extravillous Trophoblasts Cells by Interfering with Epidermal Growth Factor Receptor Signaling

The placenta supports fetal growth and is vulnerable to exogenous chemical exposures. We have previously demonstrated that exposure to the emerging chemical bisphenol S (BPS) can alter placental endocrine function. Mechanistically, we have demonstrated that BPS interferes with epidermal growth factor receptor (EGFR) signaling, reducing placenta cell fusion. Extravillous trophoblasts (EVTs), a placenta cell type that aids with vascular remodeling, require EGF to invade into the maternal endometrium. We hypothesized that BPS would impair EGF-mediated invasion and proliferation in EVTs. Using human EVTs (HTR-8/SVneo cells), we tested whether BPS could inhibit the EGF response by blocking EGFR activation. We also evaluated functional endpoints of EGFR signaling, including EGF endocytosis, cell invasion and proliferation, and endovascular differentiation. We demonstrated that BPS blocked EGF-induced phosphorylation of EGFR by acting as a competitive antagonist to EGFR. Transwell assay and a three-dimensional microfluidic chip invasion assay revealed that BPS exposure can block EGF-mediated cell invasion. BPS also blocked EGF-mediated proliferation and endovascular differentiation. In conclusion, BPS can prevent EGF-mediated EVT proliferation and invasion through EGFR antagonism. Given the role of EGFR in trophoblast proliferation and differentiation during placental development, our findings suggest that maternal exposure to BPS may contribute to placental dysfunction via EGFR-mediated mechanisms.     

低温固化型水性聚酯的合成及其水性烤漆应用

基于功能性组分羟乙基化双酚A,间苯二甲酸-5-磺酸钠以及多元醇/酸合成聚酯共聚物,并以硅烷偶联剂改性获得适合低温固化型水性烤漆的水性聚酯;研究了羟乙基化双酚A,间苯二甲酸-5-磺酸钠,支化组分以及硅烷偶联剂,与水性聚酯水溶性、贮存稳定性以及合成过程黄变的关系,确定了上述组分对水性低温固化涂层的耐化学性、耐溶剂性以及光泽...     

基于毛细管电泳的双酚E与血清白蛋白行为成像

目的 建立双酚E（BPE）与血清白蛋白相互作用快速评价方法,为双酚类化合物毒理效应研究提供有益参考。方法 使用毛细管电泳仪,应用外标Hummel-Dreyer（HD）法,测定了体外环境中BPE与血清白蛋白相互作用电泳图。采用非线性方程、Scatchard方程和Klotz方程三种函数形式分析实验数据,获得体系的相互作用参数。结果 三种不同函数形式所得到的拟合参数具有较高的一致性。BPE与血清白蛋白结合比约为2,相互作用参数表明牛血清白蛋白及人血清白蛋白的结合反应存在相似的结合位点数,且结合稳定。不同白蛋白与BPE的相互作用相似,均为非共价相互作用。结论 外标HD法作为一种简便有效的方法可以快速评价蛋白质-污染物相互作用相关问题。BPE与不同血清白蛋白具有相似的温和相互作用,这提示双酚类化合物在人体中和牛中可能具有类似的污染分布规律。     

双酚A市场发展趋势

综述了双酚A国内外产能、消费需求及其变化趋势,介绍了当前环保问题对双酚A制品市场的影响。     

高效液相色谱-串联质谱法测定饮料、牛奶和奶粉中双酚A和15种邻苯二甲酸酯

目的建立了饮料、牛奶和奶粉中双酚A及15种邻苯二甲酸酯的高效液相色谱-串联质谱分析方法。方法样品经甲醇提取,C_(18)色谱柱分离后,采用串联四极杆质谱电喷雾电离源正负离子切换多反应离子监测模式检测。结果双酚A及15种邻苯二甲酸酯在各自的线性范围内线性关系良好,相关系数均不低于0.9900,定量下限为10μg/kg,低、中、高3个加标水平下平均回收率为61.1%~129.5%,相对标准偏差为1.13%~22.12%。结论该方法具有前处理简单、灵敏度高的优点,适用于饮料、牛奶及奶粉中双酚A及15种邻苯二甲酸酯残留的确证和定量检测。     

双酚二胺型苯并噁嗪树脂的合成及表征

以双酚、甲醛和二胺为主要原料,以甲苯为溶剂,合成了苯并嗪(BOZ)中间体。采用红外光谱(FT-IR)技术对其结构进行了表征,同时采用差示扫描量热(DSC)法和热重分析(TGA)法对其固化过程及热稳定性能进行了研究。结果表明:双酚二胺类BOZ体系具有较宽的固化峰,其在200℃左右开始开环固化,具有良好的加工性能;700℃时的残炭率均超过40%(其中AFMDA体系为65%),耐温指数为185℃,说明该双酚二胺类BOZ体系是一种良好的耐高温材料,可以用于耐高温胶粘剂的制备。     

Blended resins based on a new propargyl‐functional resin: Synthesis,cure, and thermal properties

A new propargyl‐functional resin, propargyl ether bisphenol A novolac (PBPN), was synthesized, and the structure of PBPN were characterized using ¹H NMR and FTIR spectra. The PBPN was blended with 4,4′‐bismaleimide diphenyl methane (BDM) at different molar ratio to obtain the blends. Differential scanning calorimetry (DSC) was used to characterize the cure behavior of PBPN and the blends. Thermal gravimetric analysis (TGA) and dynamic mechanical analysis (DMA) were performed, respectively, to evaluate thermal stability and dynamic mechanical properties of the cured resins. The results indicate that the PBPN presented better cure and thermal properties than do traditional propargyl resins; furthermore, the cure behavior and thermal properties of PBPN could be improved remarkably by blending with BDM. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 4207–4212, 2006     

Preparation and characterization of TiO2/Ti film electrodes by anodization at low voltage for photoelectrocatalytic application

Multiporous TiO₂/Ti film electrodes were prepared by different anodic oxidation processes at low voltage, in which the micro-structured TiO₂ thick films were prepared in H₂SO₄–H₂O₂–H₃PO₄–HF solution for 2 h and the nano-structured TiO₂ thin films were prepared in H₃PO₄–HF solution for 30 min with post-calcination. Both types of TiO₂/Ti films were characterized by scanning electron microscopy and X-ray diffraction analysis. The photocatalytic (PC) and photoelectrocatalytic (PEC) reactivity of the TiO₂/Ti electrodes were evaluated in terms of bisphenol A (BPA) degradation in aqueous solution. The experimental results demonstrated that the nano-structured TiO₂/Ti thin-film electrodes had higher reactivity in the BPA degradation reaction. The PEC degradation of BPA was further studied using different cathodes, either a reticulated vitreous carbon (RVC) electrode or a platinum (Pt) electrode. The experimental results confirmed that the efficiency of BPA degradation could be significantly enhanced in the TiO₂/Ti–RVC reaction system due to the generation of H₂O₂ on the RVC cathode. It is believed that such a H₂O₂-assisted TiO₂ PEC oxidation process may have good potential for water and wastewater treatment.