测试条件对聚氯乙烯树脂稀溶液粘数的影响

聚氯乙烯树脂稀溶液粘数是聚氯乙烯树脂的一项重要指标,它的高低决定着产品的不同用途。本实验测试了几种不同测试条件如测试温度、黏度计毛细管直径、溶剂浓度等对聚氯乙烯树脂稀溶液粘数结果所产生的影响,通过实验数据的理论分析和计算,对原因进行了具体的分析。这些分析结果的获得对提高粘数分析的准确性,对于指导实际生产,规范检验操作,修订检验标准都有着重要的意义。     

Clinically Applicable Assessment of Tisagenlecleucel CAR T Cell Treatment by Digital Droplet PCR for Copy Number Variant Assessment

Chimeric antigen receptor (CAR) T cell therapy is an innovative immunotherapy for treating cancers in both children and adults with proven utility in numerous clinical trials. Significantly, some CAR T cell therapies have now been approved by relevant national regulatory bodies across numerous countries for clinical therapeutic use outside of clinical trials. One such recently licensed product is tisagenlecleucel, a CAR T therapy approved for the treatment of B-cell acute lymphoblastic leukemia (B-ALL) using autologous T cells from the patient. The genetically engineered T cells target a protein called CD19, common to B cells, through a CAR incorporating a 4-1BB costimulatory domain to improve response. Since tisagenlecleucel is now a standard of care treatment for B-ALL, it is clinically essential to be able to accurately monitor these CAR T cells in patients. Assessment of the copy number variant (CNV) of the CAR T cell products allows this within a clinically acceptable timeframe for optimal patient benefit. However, no standardized method with high reproducibility and efficiency has been described within a routine clinical laboratory setting. Here, we demonstrated a novel digital droplet PCR (ddPCR)-based methodology for the study of CNV (ddPCR-CNV) in 4-1BB CD19-specific CAR T cells with universal applicability across clinical diagnostic laboratories.     

铬硅薄膜电阻的退火工艺条件研究

分析了CrSi薄膜电阻阻值的变化机理,并以此作为理论指导,开展退火工艺条件对铬硅薄膜电阻稳定性影响的实验,得到优化的退火工艺条件,可以使铬硅薄膜电阻的温度系数减小到±0.0001℃左右,大大提高了铬硅薄膜电阻的稳定性。     

火力发电厂性能指标一致化问题的思考和建议

针对火力发电厂纯凝汽式机组主要性能指标计算的影响因素,结合国内外不同标准对于机组工况的定义,提出了性能指标计算取值过程当中存在的工况不一致的问题,分析了问题存在的原因,提出了解决问题的建议。     

某型器件工作状态记录仪的设计

为对某型器件工作状态中的几个重要参数进行全程监测和定量分析,并满足在高冲击等特殊环境下使用的要求,提出了一种基于CPLD为主控、以Flash为存储器的测试存储系统设计方案.详细阐述了硬件系统各组成模块的电路及其工作原理,给出了相应的程序设计流程图,介绍了采集中的编码方法和提高存储速度的方法.在实地测试过程中,记录仪达到...     

On-line acoustic viscometry in oil condition monitoring

The paper describes the theoretical standpoints of developing magnetoelastic viscometers and a concept of viscosity measurement. The magnetoelastic viscometer has shown the readings close to the capillary viscometer. Testing of the oils with PMMA viscosity-index improvers by viscometers has indicated changes in rheological properties observed in the non-Newtonian behavior of the oils. With increase in content or molecular weight of the improver, the non-Newtonian behavior of the oil appeared at lower frequencies of viscosity measurements.     

水热法制备粉煤灰钙基脱硫剂

文章研究了利用粉煤灰和Ca(OH)2为原料水热反应制备钙基脱硫剂。影响钙基脱硫剂钙剂利用率最主要的因素是水浴温度(TH),它的最佳值是90℃;温度上下浮动5℃,利用率将降低20%。其次还有水浴温度、粉煤灰与Ca(OH)2质量比(FC)、水固比(LS),这些因素的波动对利用率的影响相对较小。水浴时间(tH)达到8 h以上,FC在5～10的范围内变化,LS在8～18的范围内变化均能制备具有较高利用率的钙基脱硫剂。     

Experimental study of CT test on the failure of acrylate spray-applied waterproof layer in the groundwater environment

In this study the computerized tomography (CT) was first used to quantitatively analyze the failure of acrylate spray-applied waterproof membrane in the groundwater environment. The results of the CT tests show that it is feasible to use the CT to quantitatively analyze the failure of the waterproof membrane and the CT method has the advantages of speediness and accuracy that can eliminate the fussy operation process in routine tests. The main conclusions summarized from the study are as follows. First, the...     

Negative refraction of a surface plasmon polariton

We study theoretically the negative refraction of a surface plasmon polariton. The system we consider consists of a vacuum that is in a contact with two metals that each fill a quarter space with a periodic boundary between them. The interface of each of the metals with the vacuum supports a surface plasmon polariton. When a surface plasmon polariton passes through the periodic boundary between the metals it transforms partly into the Bragg beams of the refracted and reflected surface plasmon polaritons and partly into volume waves in the vacuum. A suitable choice of the period can ensure that the only propagating Bragg beams of the refracted surface plasmon polariton are the specular beam and the (?1)-order beam, which is negatively refracted. With a suitable choice for the form of the profile function and its amplitude the specular beam can be made to vanish.