Long-term high-velocity oxidation and hot corrosion testing of several NiCrAl and FeCrAl base oxide dispersion strengthened alloys

Several oxide dispersion strengthened (ODS) alloys have been tested for cyclic, long-term, high gas-velocity resistance to oxidation at 1100°C and hot corrosion at 900°C. Both nominally Ni-16Cr-4Al and Fe-20Cr-4.5Al ODS alloys were subjected up to 2500 cycles, where each cycle consisted of 1 hr in a hot, Mach 0.3 combusted gas stream followed by a 3-min quench in an ambient temperature, Mach 0.3 air blast. For comparison to existing technology, a coated superalloy was simultaneously tested. The ODS iron alloy exhibited clearly superior behavior, surviving 3800 oxidation and 2300 hot corrosion cycles essentially unscathed. While the ODS nickel alloys exhibited adequate oxidation resistance, the long-term hot corrosion resistance could be marginal, since the best life for such alloys under these conditions was only 1100 cycles. However, the hot corrosion resistance of the ODS Ni-base alloys is excellent in comparison to that of traditional superalloys.     

Enhancement of dissolution rate of valdecoxib using solid dispersions with polyethylene glycol 4000

The aim of the present study was to enhance the dissolution rate of valdecoxib using its solid dispersions (SDs) with polyethylene glycol (PEG) 4000. The phase solubility behavior of valdecoxib in the presence of various concentrations of PEG 4000 in water was obtained at 37°C. The solubility of valdecoxib increased with increasing amount of PEG 4000 in water. Gibbs free energy (ΔG°_tr) values were all negative, indicating the spontaneous nature of valdecoxib solubilization, and they decreased with increase in the PEG 4000 concentration, demonstrating that the reaction conditions became more favorable as the concentration of PEG 4000 increased. The SDs of valdecoxib with PEG 4000 were prepared at 1:1, 1:2, 1:5, and 1:10 (valdecoxib: PEG 4000) ratio by melting method. Evaluation of the properties of the SDs was performed by using dissolution, Fourier-transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), X-ray diffraction (XRD), and scanning electron microscopy (SEM) studies. The SDs of valdecoxib with PEG 4000 exhibited enhanced dissolution rate of valdecoxib, and the rate increased with increasing concentration of PEG 4000 in SDs. Mean dissolution time (MDT) of valdecoxib decreased significantly after preparation of SDs and physical mixture with PEG 4000. The FTIR spectroscopic studies showed the stability of valdecoxib and absence of well-defined valdecoxib-PEG 4000 interaction. The DSC and XRD studies indicated the amorphous state of valdecoxib in SDs of valdecoxib with PEG 4000. The SEM pictures showed the formation of effective SDs of valdecoxib with PEG 4000, since well-defined changes in the surface nature of valdecoxib, SDs, and physical mixture were observed.     

Celecoxib-cyclodextrin systems: characterization and evaluation of in vitro and in vivo advantage

Solid dispersions of Celecoxib were prepared with hydroxypropyl β cyclodextrin by various methods such as physical mixture, cogrinding, kneading, and coevaporation. The dispersions were characterized by differential scanning calorimetry (DSC), X-ray diffraction patterns, infrared spectroscopy, and nuclear magnetic resonance studies. The DSC thermograms of the dispersions indicated potential of heat-induced interaction between Celecoxib and cyclodextrin that could influence in vitro drug dissolution. The dispersions exhibited faster rates of dissolution compared to that of Celecoxib. The kneaded dispersion with the fastest in vitro dissolution rate when compressed into tablets showed a better release profile compared to the tablets of pure Celecoxib. In vivo studies revealed that the kneaded dispersion provided for quicker response and was more effective in inhibiting rat paw edema as compared to Celecoxib alone, thus confirming the advantage of improved pharmacological activity of Celecoxib when administered as a solid dispersion with cyclodextrin.     

瞬态啁啾对色散支持传输系统的影响

本文分析和计算了瞬态啁啾对色散支持传输（Ｄｉｓｐｅｒｓｉｏｎ－ＳｕｐｐｏｒｔｅｄＴｒａｎｓｍｉｓｓｉｏｎ）系统的作用，结果表明，在高速调制下瞬态啁啾可能严重影响系统性能。最后对如何改善系统性能进行了讨论。     

地下水溶质径向弥散问题的混合拉普拉斯变换有限单元解

本文采用混合拉普接斯变换有限单元法，求解地下水溶质径向弥散问题，通过与精确解析解、数值解及砂槽试验资料对比，表明该算法效率高、精度好、能有效地克服数值困难。     

光纤放大器的增益色散对孤子传输的影响

本文用微扰法近似求解了含增益色散效应的ＮＬＳ方程，由此解讨论了光纤放大器的增益色散对孤子的幅值和形状的影响。     

非接触式高压静电场微胶囊制备方法

为制备脂肪干细胞微胶囊,设计并研制基于高压静电成囊原理的非接触式微囊发生装置。以海藻酸钠在氯化钙溶液中成囊的方法制备细胞微胶囊,并分析电场电压、推进速度、电极距离和针头型号等参数对所制微囊粒径的影响。采用非接触式微囊发生器能制备出表面光滑、形状规则、大小均匀的微胶囊。用该装置制备出微囊化脂肪干细胞,经过一周培养,细胞在微胶囊中存活良好,增殖明显。     

光正交频分复用技术的原理、应用与发展

由于光正交频分复用具备自适应色散补偿能力,它在大容量、长距离光通信系统中有广阔的应用前景.文章主要介绍光正交频分复用技术的基本原理,跟踪该技术目前在国际上的发展状况,讨论其存在的主要技术问题,并展望它在未来的发展.     

色散平坦渐减光纤中自相似脉冲演化特性研究

从脉冲在光纤中传输所满足的非线性薛定谔方程出发,采用分布傅里叶方法对脉冲在色散平坦渐减光纤中自相似脉冲演化特性进行了研究。结果表明：双曲正割脉冲在不同初始能量和初始脉冲宽度的情况下,色散平坦渐减光纤可以产生带有线性啁啾的自相似脉冲。进一步研究表明,随着初始啁啾增加,脉冲逐渐展宽且展宽速度逐渐加快,而演化特性的劣化程度随啁啾参量的增加而增大;当初始啁啾为正时自相似脉冲演化特性劣于负啁啾时的特性。     

量化线性离散码性能分析

文章研究了量化线性离散码的系统模型和性能。通过对线性离散码码字矩阵每一个元素的实部和虚部进行量化,试图找到消耗较少存储资源,并具有与原码字相似比特差错率（Bit Error Rate,BER）的码字。仿真结果表明：这样的码字可以通过对原线性离散码进行量化处理得到。