高速电弧喷涂FeMnCrNi/Cr3C2涂层的工艺优化及磨损性能

采用高速电弧喷涂技术在Q235钢表面制备了FeMnCrNi/Cr₃C₂涂层。通过正交试验研究了喷涂电压、喷涂电流和喷涂距离对涂层形貌及性能的影响,获得了涂层制备的最佳工艺参数。利用扫描电镜、X射线衍射仪、能谱仪、显微硬度仪与激光共聚焦显微镜等研究了最佳工艺参数下制备的FeMnCrNi/Cr₃C₂涂层的形貌及性能。结果表明:影响涂层性能的主次因素顺序为:喷涂距离、喷涂电压、喷涂电流。最佳工艺参数为:喷涂电压31 V、喷涂电流240 A、喷涂距离200 mm。采用最佳工艺参数制备的涂层孔隙率为1.99%,显微硬度为719 HV0.1,是Q235钢的3.5倍,涂层的平均磨痕宽度、深度和截面积分别为281.95μm、4.42μm和564.81μm2,相比Q235钢分别减小了60%、72%和89%,具有更优的耐磨性;涂层的主要磨损形式为磨粒磨损。     

Glass formation in Fe-Cr-Zr-B-Mo alloys by tuning Nb addition

Fe-based bulk metallic glasses (BMGs) with high boron content have potential application as a coating material used in the framework for storing spent nuclear fuels to support their safe long-term disposal. The high glass forming ability (GFA) and large supercooled liquid region are therefore required for such Fe-based BMGs in either the glassy powder fabrication or the subsequent coating spraying. In order to meet these requirements, the influence of Nb content on the GFA of Fe₅₇Cr₁₀Zr₈B₁₈Mo_7−xNb_x (x=1–5, at.%) alloys was investigated, as Nb has positive roles in GFA and thermal stability of BMGs. The results indicate that a fully amorphous phase in the as-cast samples with 3 mm in diameter is obtained for both the Fe₅₇Cr₁₀Zr₈B₁₈Mo₅Nb₂ and Fe₅₇Cr₁₀Zr₈B₁₈Mo₄Nb₃ alloys. The corresponding supercooled liquid regions of the two BMGs are 78 K and 71 K, respectively. The mechanism for improving their GFA was analyzed based on the principle of metal solidification, the parameters for glass formation and thermal properties of the alloys. The compression strength and Vicker’s hardness of the two BMGs are 1,950 MPa and 1,310 HV, 2,062 MPa and 1,180 HV, respectively. The developed BMGs with high B content, good GFA, and very high hardness can be used as coating materials to the framework for spent nuclear fuels.

     

消防设备电源监控传感模块设计

针对市面上消防设备电源监控传感器采样精度差、通信不稳定、不符合国标规范等设计缺陷,以国家标准GB28184-2011《消防设备电源监控系统》为依据研究设计了一款电流电压型监控传感器。设计创新点在于采用RN8209G芯片进行采样,并通过CAN总线进行通信,在0~50 A电流范围内提高采样精度达到1%。设计产品已通过国标GB28184中4.7节表1中的基础实验及高低温试验要求。     

电动自行车用便携式充电器的质量安全风险研究

近年来,电动自行车在充电过程中发生的火灾事故频发,给人民群众的生命财产安全带来极大危险。通过风险监测研究发现,电动自行车用便携式充电器存在消耗功率大,输出电流大,充电时无人照看,使用环境恶劣等多个风险源。本文通过试验分析,揭示了此类产品的本身质量问题和由于使用不当所造成的安全风险。     

Catalytic combustion kinetics of isopropanol over novel porous microfibrous‐structured ZSM‐5 coating/PSSF catalyst

Porous thin‐sheet cobalt–copper–manganese mixed oxides modified microfibrous‐structured ZSM‐5 coating/PSSF catalysts were developed by the papermaking/sintering process, secondary growth process, and incipient wetness impregnating method. Paper‐like sintered stainless steel fibers (PSSF) support with sinter‐locked three‐dimensional networks was built by the papermaking/sintering process, and ZSM‐5 coatings were fabricated on the surface of stainless steel fibers by the secondary growth process. Catalytic combustion performances of isopropanol at different concentrations over the microfibrous‐structured Co–Cu–Mn (1:1:1)/ZSM‐5 coating/PSSF catalysts were measured to obtain kinetics data. The catalytic combustion kinetics was investigated using power–rate law model and Mars–Van Krevelen model. It was found that the Mars–Van Krevelen model provided fairly good fits to the kinetic data. The catalytic combustion reaction occurred by interaction between isopropanol molecule and oxygen‐rich centers of modified microfibrous‐structured ZSM‐5 coating/PSSF catalyst. The reaction activation energies for the reduction and oxidation steps are 60.3 and 57.19 kJ/mol, respectively. © 2014 American Institute of Chemical Engineers AIChE J, 61: 620–630, 2015     

Nanosponge-based pediatric-controlled release dry suspension of Gabapentin for reconstitution

Abstract

Context: Gabapentin was selected to formulate oral controlled release dry suspension because of short biological half life of 5–7?h and low bioavailability (60%). Gabapentin is a bitter drug so an attempt was made to mask its taste.

Objective: To formulate and evaluate controlled release dry suspension for reconstitution to increase the bioavailability and to control bitter taste of drug.

Materials and methods: Cyclodextrin based nanosponges were synthesized by previously reported melt method. The nanosponge–drug complexes were characterized by FTIR, DSC and PXRD as well as evaluated for taste and saturation solubility. The complexes were coated on Espheres by a suspension layering technique followed by coating with ethyl cellulose and Eudragit RS-100. A dry powder suspension for reconstitution of the microspheres was formulated and evaluated for taste, redispersibility, in vitro dissolution, sedimentation volume, leaching and pharmacokinetics.

Results and discussion: The complexes showed partial entrapment of drug nanocavities. Significant decrease in solubility (25%) was observed in the complexes than pure drug in different media. The microspheres of nanosponge complexes showed desired controlled release profile for 12?h. Insignificant drug leaching was observed in reconstituted suspension during storage for 7 days at 45?°C/75% RH. Nanosponges effectively masked the taste of Gabapentin and the coating polymers provided controlled release of the drug and enhanced taste masking. The results of in vivo studies showed increase in bioavailability of controlled release suspension by 24.09% as compared to pure drug.

Conclusion: The dry powder suspension loaded with microspheres of nanosponges complexes can be proposed as a suitable controlled release drug delivery for Gabapentin.     

Preparation and IVIVC evaluation of salvianolic acid B micro-porous osmotic pump pellets

Purpose: Salvianolic acid B micro-porous osmotic pump controlled release pellets (SalB-CRPs) with suitable in vitro release profiles and good in vitro and in vivo correlation (IVIVC) were developed.

Method: Extrusion-spheronization was used to prepare the starter cores containing SalB/MCC/Kollidon®CL-SF/Flowlac®100 of 30:40:15:15 [w/w, The formulation composition of SalB immediate-release pellets (SalB-IRPs)] and complexed with lactose. The pellets were subsequently coated with Surelease aqueous dispersion to achieve controlled-release properties. Furthermore, a single-dose pharmacokinetics study was carried out in New Zealand White (NZW) rabbits.

Results: In the starter cores, the lactose content was 25% based on the SalB-IRPs constituent. The optimal coating polymer ratio of Surelease aqueous dispersion and polyvinyl alcohol–polyethylene glycol (PVA–PEG) graft copolymer (EC/PVA–PEG) was found to be 70:30 (w/w, %) with a coating weight of 5%. The prepared SalB-CRPs had similar in vitro release under three different pH release mediums. A good IVIVC was characterized by a high coefficient of determination (r?=?0.9801). The in vivo study indicated that the maximum plasma concentration (C_max) of SalB-CRPs was decreased, peak concentration time (T_max) and mean residence time (MRT) were all prolonged, as that of SalB-IRPs. In addition, the area under concentration–time curve from 0 to 24?h (AUC_0–24?h) and 0 to infinity (AUC_0–∞) were significantly higher, compared with those of SalB-IRPs.

Conclusion: Collectively, these results manifested that SalB-CRPs were likely to be a more suitable formulation in treating cardiovascular disease with improved in vivo retention, decreased plasma drug concentration fluctuation.     

Influence of Particle Size and Heating Rate on Decomposition of BC Dry Chemical Fire Extinguishing Powders

Pyrolysis of BC dry chemical fire extinguishing powders which are useful for Class “B” and Class “C” fires was conducted on a thermogravimetric analyzer with sample loading of 10–25 mg under dynamic air atmosphere. The effect of particle sizes (medium value 48.99, 27.24, 4.93 µm) and heating rates (10, 15, and 20°C min^?1) were examined. The pyrolysis kinetics of the samples was analyzed using a distribution activation energy model. It was found that the decomposition temperature decreased and the pyrolysis rate increased after the samples were milled. The agglomeration of particles during production did not have an appreciable influence on the pyrolysis process of the samples in our experimental conditions. The activation energy value was 77.13?219.78 kJ · mol^?1, 58.18?288.67 kJ · mol^?1, and 44.59?209.17 kJ · mol^?1 for the powder of particle size 48.99, 27.24, 4.93 µm. We should use micro powder in fire extinguishing.     

以车代磨加工柱塞喷涂层的工艺性能研究

针对柱塞喷涂重熔后磨削加工用时长,效率低,严重影响产品生产周期这一瓶颈问题,本文介绍了一种安全可靠、简单可行的新工艺方法,并通过这种以车代磨新工艺方法的探究和工艺参数的验证与实施,缩短了喷涂柱塞的加工周期,大幅度的提高了加工效率,很好地解决了喷涂柱塞加工周期长,效率低这一生产瓶颈问题。既提高了喷涂柱塞的产品质量,又极大的降低了加工成本,也为喷涂层这种高硬度材料的高效硬加工进行了很有意义的探索,并有很好的推广价值。