多室内环流反应器中液体循环量的试验验证与模拟

目的 对液相氧化脱硫多室内环流反应器液体循环量的影响因素进行模拟和验证。方法 采用CFD数值模拟,基于欧拉-欧拉多相流模型,对液相氧化脱硫多室内环流反应器进行气液两相流模拟,考查了酸气流量和空气流量对液体循环量的影响。结果 利用数值模拟得到的液体循环量与利用靶式流量计测得的液体循环量误差小于10%。当酸气中H₂S体积分数不超过3%时,液体循环量(z)与酸气流量(x)、空气流量(y)之间的关系式为：z=-474.996+0.358x+0.487 3y。结论 欧拉-欧拉两相流模型能够准确地预测液相氧化脱硫反应器内液体循环量。     

瓦斯突出预测敏感指标的确定方法研究

通过模糊数学与概率论相结合分析,提出确定预测敏感指标的数学模型,把抽象的敏感指标确定问题通过具体的数值表示出来。实践证明,该模型预测的结果与实际相吻合,该模型的建立对突出矿井确定其敏感指标具有一定的参考价值。     

抽放方法治理采煤工作面上隅角瓦斯

针对高瓦斯工作面上隅角瓦斯大,严重影响安全,制约生产的问题,采用直接抽放工作面上隅角瓦斯及顶板抽放法取得成功。实践证明顶板抽放法是解决高瓦斯采面瓦斯问题非常有效和更为安全的方法。     

抽出式风机在治理工作面上隅角瓦斯的应用

针对漳村煤矿综采工作面上隅角瓦斯浓度高的情况,用抽出式风机处理上隅角瓦斯,较好地解决了上隅角瓦斯频繁超限事故,实现了矿井的安全生产。     

天然气置换后铸铁管承插接口漏气对策

分析了天然气置换人工煤气后铸铁管道承插接口漏气原理,介绍了4种解决方案:管道更换、PE管内衬、接口修补及燃气加湿,对其进行了技术经济比较。     

焦作矿区煤层瓦斯合理预抽期的研究

主要介绍了合理预抽期确定模型在焦作矿区的应用。为了减少瓦斯突出的危险性,合理地确定预抽期是瓦斯抽放的关键因素之一。     

高瓦斯自燃煤层综放工作面瓦斯综合治理

通过对高瓦斯自燃煤层综采放顶煤回采工作面的瓦斯涌出考察,及对瓦斯涌出与风量、高抽巷布置、推进速度、周期来压的关系分析,提出瓦斯综合治理措施,在实践中取得较好成效。     

门站调压系统自动识别选路装置的设计

介绍了天然气门站调压系统中自动识别选路装置的设计原则,探讨了自动识别选路装置的结构及控制过程。当运行路超压切断或不能满足下游用气时,备用路能自动启动供气。当运行路超压时,运行路紧急切断阀关闭,而备用路紧急切断阀不动作。     

深圳市天然气安全应急储备及事故气源的研究

分析了深圳市建设天然气安全应急储备及事故气源的必要性,通过对深圳市天然气产业链中各环节之间相互关系的分析,提出了建设实施方案。     

Dried Blood Spots as Matrix for Evaluation of Valproate Levels and the Immediate and Delayed Metabolomic Changes Induced by Single Valproate Dose Treatment

The immediate and delayed metabolic changes in rats treated with valproate (VPA), a drug used for the treatment of epilepsy, were profiled. An established approach using dried blood spots (DBS) as sample matrices for gas chromatography/mass spectrometry-based metabolomics profiling was modified using double solvents in the extraction of analytes. With the modified method, some of the previously undetectable metabolites were recovered and subtle differences in the metabolic changes upon exposure to a single dose of VPA between males and female rats were identified. In male rats, changes in 2-hydroxybutyric acid, pipecolic acid, tetratriacontane and stearic acid were found between the control and treatment groups at various time points from 2.5 h up to 24 h. In contrast, such differences were not observed in female rats, which could be caused by the vast inter-individual variations in metabolite levels within the female group. Based on the measured DBS drug concentrations, clearance and apparent volume of distribution of VPA were estimated and the values were found to be comparable to those estimated previously from full blood drug concentrations. The current study indicated that DBS is a powerful tool to monitor drug levels and metabolic changes in response to drug treatment.