用变频器实现水库泄洪闸的智能控制

针对传统泄洪闸控制系统的通病,采用通用变频控制技术改造泄洪闸电机控制系统实现智能控制,该方案应用于工程实践,效果良好.     

双鼠笼感应电机M-S、I-S曲线计算和仿真

基于三相双鼠笼感应电动机的等效电路,本文推导出一种计算双鼠笼双端环感应电动机M-S与I-S曲线的方法,并利用计算机编程实现对电动机运行过程中的整个转矩、电流曲线进行仿真,提高了分析曲线的效率和设计准确度,为新产品设计、电机故障检查提供强有力的依据。     

From Molecules to Behavior in Long-Term Inorganic Mercury Intoxication: Unraveling Proteomic Features in Cerebellar Neurodegeneration of Rats

Mercury is a severe environmental pollutant with neurotoxic effects, especially when exposed for long periods. Although there are several evidences regarding mercury toxicity, little is known about inorganic mercury (IHg) species and cerebellum, one of the main targets of mercury associated with the neurological symptomatology of mercurial poisoning. Besides that, the global proteomic profile assessment is a valuable tool to screen possible biomarkers and elucidate molecular targets of mercury neurotoxicity; however, the literature is still scarce. Thus, this study aimed to investigate the effects of long-term exposure to IHg in adult rats’ cerebellum and explore the modulation of the cerebellar proteome associated with biochemical and functional outcomes, providing evidence, in a translational perspective, of new mercury toxicity targets and possible biomarkers. Fifty-four adult rats were exposed to 0.375 mg/kg of HgCl₂ or distilled water for 45 days using intragastric gavage. Then, the motor functions were evaluated by rotarod and inclined plane. The cerebellum was collected to quantify mercury levels, to assess the antioxidant activity against peroxyl radicals (ACAPs), the lipid peroxidation (LPO), the proteomic profile, the cell death nature by cytotoxicity and apoptosis, and the Purkinje cells density. The IHg exposure increased mercury levels in the cerebellum, reducing ACAP and increasing LPO. The proteomic approach revealed a total 419 proteins with different statuses of regulation, associated with different biological processes, such as synaptic signaling, energy metabolism and nervous system development, e.g., all these molecular changes are associated with increased cytotoxicity and apoptosis, with a neurodegenerative pattern on Purkinje cells layer and poor motor coordination and balance. In conclusion, all these findings feature a neurodegenerative process triggered by IHg in the cerebellum that culminated into motor functions deficits, which are associated with several molecular features and may be related to the clinical outcomes of people exposed to the toxicant.     

变频调速在斗轮堆取料机行走控制系统中的应用

采用变频器在斗轮堆取料机行走机构驱动中进行变频调速,整机运行平稳,无震动,可提高整机结构安全可靠性,延长行走减速机主要零部件的使用寿命,使故障及检修率下降,系统的控制水平大大提高。     

混合磁路多边耦合电机的转矩提升功能

为对混合磁路多边耦合电机在提升电磁转矩方面的作用做一分析,通过理论分析和实验研究对比这种电机和同体积的混合式步进电机的电磁转矩,说明该结构的电机在提升电磁转矩方面的作用.运用等值磁网络模型的方法解析得到混合磁路多边耦合电机的电磁转矩,指出电磁转矩中含有永磁体转矩、磁阻转矩和轴向线圈转矩3种成分,其中轴向线圈转矩的存在是混合磁路多边耦合电机转矩较混合式步进电机转矩增加的原因.实验结果说明了轴向线圈在提高电机电磁转矩,提高电机铁心利用率方面的作用.     

轴径向气隙混合磁路多边耦合电机的弱磁控制

在电机轴向引入励磁线圈,使电机主磁场的磁通可调.控制轴向线圈电流的大小和方向,可以实现增磁控制和弱磁控制,可控制电枢绕组电流全部为转矩电流,从而简化了电枢绕组电流的控制.给出了电机的结构,通过解析和仿真分析了增磁和弱磁控制的方案,并进行了相应的实验.理论分析和实验结果表明,增磁控制使得电机具有低速大转矩特性,弱磁控制使得电机高速接近恒功率的特性,能够满足电动车驱动等宽调速范围应用的需要.     

煤矿锚杆机除尘马达改进

针对煤矿进口锚杆机除尘马达频繁出现故障的情况,通过排查除尘装置的安装方式和监测马达工作时的压力状态,查找故障原因,并制定解决方案。通过马达外接单向阀,可满足马达进油口最低安全压力限制的要求,解决了马达频繁损坏的问题,保障了设备工作的稳定性,提高了工作效率。     

机动车行进中自动除尘系统的研究

介绍了机动车行进中自动除尘系统的除尘原理、技术重点、试验方法和结果,突出表现其利用造振路面及该路面上的水层除尘,并能将除尘废水经除油、絮凝沉淀后达到清水回用的显著特点,由此说明机动车行进中自动除尘系统是一个新型洗车循环系统,具有推广应用前景。     

贮存条件对毛刷式装药结构火箭发动机固药力的影响

为研究贮存条件对毛刷式装药结构火箭弹发动机固药力的影响,分别选取已在温带、热带、亚热带内陆和亚热带沿海4个地区、仓库和野外两种不同场地贮存5a的32发火箭弹发动机,首先利用拉力机对每发火箭弹发动机不同位置的8根推进剂固药力进行了测定,然后根据秩和检验方法对实验结果进行了处理与分析。通过实验与分析,得到32发火箭弹发动机的固药力,测定结果的平均值为62、11～134．79N;对于同一种贮存场地,温带与热带、热带与亚热带内陆、热带与亚热带沿海贮存地区发动机固药力之间有显著差异,其他贮存地区发动机固药力之间没有显著差异;而对于同一个地区,贮存场地对火箭发动机的固药力没有显著影响。     

Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder. There is no cure and current treatments fail to slow the progression of the disease. Epigenetic modulation in the acetylation state of NF-kB RelA and the histone 3 (H3) protein, involved in the development of neurodegeneration, is a drugable target for the class-I histone deacetylases (HDAC) inhibitors, entinostat or valproate, and the AMP-activated kinase (AMPK)-sirtuin 1 pathway activator, resveratrol. In this study, we demonstrated that the combination of valproate and resveratrol can restore the normal acetylation state of RelA in the SOD1(G93A) murine model of ALS, in order to obtain the neuroprotective form of NF-kB. We also investigated the sexually dimorphic development of the disease, as well as the sex-sensibility to the treatment administered. We showed that the combined drugs, which rescued AMPK activation, RelA and the histone 3 acetylation state, reduced the motor deficit and the disease pathology associated with motor neuron loss and microglial reactivity, Brain-Derived Neurotrophic Factor (BDNF) and B-cell lymphoma-extra large (Bcl-xL) level decline. Specifically, vehicle-administered males showed earlier onset and slower progression of the disease when compared to females. The treatment, administered at 50 days of life, postponed the time of onset in the male by 22 days, but not in a significant way in females. Nevertheless, in females, the drugs significantly reduced symptom severity of the later phase of the disease and prolonged the mice’s survival. Only minor beneficial effects were produced in the latter stage in males. Overall, this study shows a beneficial and sexually dimorphic response to valproate and resveratrol treatment in ALS mice.