中医方剂与图集的转换方法

中药复方数据挖掘研究是将我国丰富的中药信息资源和现代最新信息技术相结合的重要内容,它意味着基于中医理论,利用知识发现技术,对传统中药新药、中医组方理论及规律、中药作用机制、有效成分构效关系等多个方面进行全面、系统的研究。图作为一种经典的数据结构,被广泛用于复杂数据结构分析与建模。文章探讨了图建模技术并实现了中医方剂与图集的转换。     

SVM-based ontology matching approach

There are a lot of heterogeneous ontologies in semantic web, and the task of ontology mapping is to find their semantic relationship. There are integrated methods that only simply combine the similarity values which are used in current multi-strategy ontology mapping. The semantic information is not included in them and a lot of manual intervention is also needed, so it leads to that some factual mapping relations are missed. Addressing this issue, the work presented in this paper puts forward an ontology matching approach, which uses multi-strategy mapping technique to carry on similarity iterative computation and explores both linguistic and structural similarity. Our approach takes different similarities into one whole, as a similarity cube. By cutting operation, similarity vectors are obtained, which form the similarity space, and by this way, mapping discovery can be converted into binary classification. Support vector machine (SVM) has good generalization ability and can obtain best compromise between complexity of model and learning capability when solving small samples and the nonlinear problem. Because of the said reason, we employ SVM in our approach. For making full use of the information of ontology, our implementation and experimental results used a common dataset to demonstrate the effectiveness of the mapping approach. It ensures the recall ration while improving the quality of mapping results.     

基于描述逻辑的OntoUML模型的形式化表示

将形式本体理论应用于UML语言的改进是UML的形式化研究的主要方法之一,其中On-toUML是一个概念上完整、语义上清晰和更具本体意义的UML版本。虽然OntoUML基于本体对UML进行了扩充,提供了更为丰富,更能表达现实世界语义的建模原语,但其表达方式不利于在信息系统的设计与开发中应用。本文基于描述逻辑对OntoUML中的关键建模原语及其关系给出了SHIQ形式化表示方法,并进行了实例研究。该方法表达精练、语义清晰,不仅能够表达逻辑清晰的模型,而且保证模型能够正确反映领域事实。这种形式化方法为信息系统概念建模方法提供了理论和应用支撑,在一定程度上推动了OntoUML更为广泛的应用。     

基于图的语义网络构造算法研究

在自然语言处理的基础上,将中医领域本体与图的基本性质相结合,提出了构造中医诊疗知识语义网络算法。给出了图的基本性质、语义网络的图定义,并为知识的网络表示建立了相应的数据结构。将算法用于中医领域语义网络和语义场构建。试验结果表明,该算法具有较好的实用性。提出的基于图的语义网络构造算法,对于文本挖掘、知识获取技术研究有重要意义,也是中医专家知识获取的有效方法。     

基于知识的P2P网格资源发现研究*

针对当前网格资源管理系统扩展性差的问题,提出了具有分布式本体知识库的网格资源管理模型.新模型由分布的多个自治管理域组成;自治域之间通过DHT覆盖网连接.网格资源信息以本体知识库的形式管理:本地知识库管理域内网格知识;全局知识库则提供分布本体的语义映射以及知识的索引和定位.资源发现转换为本体知识库的实例检索推理,并且支持跨管理域的资源集发现.新模型极大地提高了网格资源管理系统的可扩展性.     

多信息源下本体自动抽取的实现*

以关系型数据库、XML文件、HTML文件、一般文档为信息源,运用不同的方法分别将多信息源映射为概念图,并按照拟定的概念逻辑结构进行统一存储,最后运用抽取算法实现本体的自动抽取.     

Catalase (CAT) Gene Family in Rapeseed (Brassica napus L.): Genome-Wide Analysis,Identification, and Expression Pattern in Response to Multiple Hormones and Abiotic Stress Conditions

Catalase (CAT) is an antioxidant enzyme expressed by the CAT gene family and exists in almost all aerobic organisms. Environmental stresses induce the generation of reactive oxygen species (ROS) that eventually hinder plant growth and development. The CAT enzyme translates the hydrogen peroxide (H₂O₂) to water (H₂O) and reduce the ROS levels to shelter the cells’ death. So far, the CAT gene family has not been reported in rapeseed (Brassica napus L.). Therefore, a genome-wide comprehensive analysis was conducted to classify the CAT genes in the rapeseed genome. The current study identified 14 BnCAT genes in the rapeseed genome. Based on phylogenetic and synteny analysis, the BnCATs belong to four groups (Groups I–IV). A gene structure and conserved motif analysis showed that Group I, Group II, and Group IV possess almost the same intron/exon pattern, and an equal number of motifs, while Group III contains diverse structures and contain 15 motifs. By analyzing the cis-elements in the promoters, we identified five hormone-correlated responsive elements and four stress-related responsive elements. Further, six putative bna-miRNAs were also identified, targeting three genes (BnCAT4, BnCAT6, and BnCAT8). Gene ontology (GO) enrichment analysis showed that the BnCAT genes were largely related to cellular organelles, ROS response, stimulus response, stress response, and antioxidant enzymes. Almost 10 BnCAT genes showed higher expression levels in different tissues, i.e., root, leaf, stem, and silique. The expression analysis showed that BnCAT1–BnCAT3 and BnCAT11–BnCAT13 were significantly upregulated by cold, salinity, abscisic acid (ABA), and gibberellic acid (GA) treatment, but not by drought and methyl jasmonate (MeJA). Notably, most of the genes were upregulated by waterlogging stress, except BnCAT6, BnCAT9, and BnCAT10. Our results opened new windows for future investigations and provided insights into the CAT family genes in rapeseed.     

结合相关规则和本体加权图的查询扩展

针对现有信息检索系统查询性能的不足,提出了一种结合相关规则和WordNet本体信息的查询扩展方法.该方法借助相关规则挖掘和WordNet本体信息构建加权词语关系图,并根据加权图的结构和权重信息计算扩展词的重要性.查询时,从这个图中取原查询词的最邻近词作为扩展词来源,选取其中权重最大的p个词返回并进行二次检索.在实现算法的基础上,通过Lucene全文检索器进行实验,将所得的结果值F1与其他算法的结果作比较.比较结果表明,该方法比不作扩展的检索有约16.93％的性能提升.     

基于本体的文档互操作度量模型

为客观、自动化地评价各种文档在不同情况下实际达到的互操作能力,提出利用本体技术建立文档互操作性度量模型。在准确、形式化地描述文档概念及其关联的基础上,综合考虑各种影响互操作性的度量因素,通过度量函数对不同文档系统间的互操作性进行计算,通过量化的结果为互操作性测评提供客观依据。基于本体的形式化描述,实现了一个面向办公文档领域的原型系统以自动化地进行文档互操作性度量,验证了度量模型构建方法的有效性和模型的实用性。     

Web服务质量建模及其正确性验证

针对现有的Web服务质量模型主要考虑的都是通用的服务质量属性,没有考虑特定的Web服务属性在评价中的作用,提出了一个新的Web服务质量模型,它引入了一个特定领域的服务质量属性,该模型包括三个子模型。模型中建立了相关的服务质量树和目标对象树,通过量化指标子模型对目标对象进行量化,形成相应的服务权重树。该模型既可适应用于单个的Web服务请求,也可以用于多个服务组合而成的请求。通过一个应用实例验证了模型的正确性和可用性。