基于SiP技术的胶囊内窥镜微型电路系统制造

胶囊内窥镜是近年发展起来的微型医疗仪器,其电路构造具有体积小、功能全等特点。文章提出用高密度封装SiP技术实现胶囊内窥镜的电路系统微型化。相对传统的芯片定制方式,采用堆叠式、表面贴装式或倒装焊式等组装方式具有成本低、难度低、开发周期短的优点。SiP封装、埋植式元件基板制造等高密度封装技术的不断发展,使得采用普通商用芯片实现胶囊内窥镜电路系统制造具有可行性。     

重庆巫山龙骨坡遗址危岩抢险勘察技术应用

对重庆巫山龙骨坡遗址危岩的稳定性状态进行了分析,并根据现场实地调查结果,提出了危岩的治理方法,同时通过对危岩的加固研究,指出采用该方法达到了保护遗址的效果,解决了危岩对遗址的危险程度的勘察问题,为进一步设计加固保护遗址提供了数据。     

矿山企业事故应急救援体系建设探讨

介绍了企业建立、完善应急救援体系,提高企业防灾减灾能力,增强员工事故防范能力,从而提升企业安全生产水平。     

白象山铁矿F4断层突水应急救援方案分析

矿井突水一直是困扰矿山企业安全生产的突出问题。以马钢集团姑山矿业有限责任公司白象山铁矿F4断层突水事故应急救援为实例,通过对F4断层突水抢险救灾经过和应急救援方案的整理分析,提出了事故应急响应信息流程并总结了抢险成功的几个原因。     

Coping strategies and collective efficacy as mediators between stress appraisal and quality of life among rescue workers.

Fire-fighters, paramedics, and emergency medical technicians routinely confront potentially traumatic events in the course of their jobs. The mediation role of coping strategies and collective efficacy in the relationship between stress appraisal and quality of life was examined (compassion satisfaction, compassion fatigue, and burnout) in a correlational study. Participants were 463 Italian rescue workers (fire fighters and different categories of emergency health care professionals). Participants filled out measures of stress appraisal, collective efficacy, coping strategies, and quality of life. The results showed that emotion and support coping, self-blame coping, and self-distraction mediated the relationship between stress appraisal and compassion fatigue. Moreover, collective efficacy, self-blame coping, and religious coping mediated the relationship between stress appraisal and burnout. Finally, collective efficacy, self-blame coping, and problem-focused coping mediated the relationship between stress appraisal and compassion satisfaction. Cognitive restructuring and denial did not mediate the relation between stress appraisal and any of the quality of life dimensions. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

围岩含水条件下快速测压工艺

围岩含水条件下,高压注浆可以实现封堵渗水裂隙,利用胶囊粘液封孔法传统与改进工艺对比测定煤层瓦斯压力,通过在平煤天安十一矿的试验与应用对比,从而在实践中论证了胶囊粘液封孔-补气法快速测压的可行性。     

Process for overcoming drug retention in hard gelatin inhalation capsules

The quantity and consistency of drug delivery from dry powder inhalation devices that incorporate a pre-measured dose in a hard shell capsule of gelatin or other compatible material can be negatively affected by mold release lubricants used in capsule manufacturing. This paper describes a novel process employing supercritical CO₂ for selective extraction of the fraction of lubricant responsible for the observed high and inconsistent drug retention in capsules and the ensuing lack of reproducibility of drug delivery. The process allows for lubricant removal from seemingly inaccessible interior surfaces of assembled capsule shells without altering the structural or chemical properties of the capsules. Diffusion limitations are overcome through repeated pressure increase and decrease to generate significant convective flow of dissolved lubricant out of the capsule. Drug retention is alleviated only if nearly all the retentive fraction of the lubricant is removed. The effect of extraction with supercritical CO₂ on the structure of the internal surfaces of the capsules is investigated using scanning electron microscopy. Key performance parameters such as drug and carrier retention and fine particle mass are investigated using simulated inhalation tests. Laboratory and pilot scale extractions yielded similar results.     

Local dopamine production in the dorsal striatum restores goal-directed behavior in dopamine-deficient mice.

To determine whether dopamine signaling in the dorsal striatum is sufficient for performance of goal-directed behaviors, local dopamine production was restored in the dorsal striatum of dopamine-deficient (DD) mice through viral-mediated gene therapy. Virally rescued DD (vrDD) mice were tested for learning of an appetitive T-maze task designed to measure goal-directed behavior. The results indicate that in contrast with the performance of DD mice that have dysregulated dopamine signaling, vrDD mice were able to perform the T-maze task and reverse their behavior as well as sham-operated control mice. The authors conclude that finely tuned dopaminergic signaling within the dorsal striatum is sufficient for performance of goal-directed behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

一个适用于无线内窥镜系统的ASK中频接收机电路

实现了一个适用于无线内窥镜系统的低功耗ASK中频接收机电路.该接收机包括一个用于补偿信道衰减的自动增益控制环、一个ASK解调器和基于能隙基准源的偏置电路,接收机电路已采用0.25μm CMOS工艺实现.测试结果表明,该电路可以从功率在-30～10dBm之间的中频信号中正确解调出数字基带信号,中频工作频率为20MHz.电路采用2.5V电源,消耗的电流仅为2.1mA.     

中温胶囊过破胶技术

胶囊过破胶技术是应用胶囊破胶剂使压裂液短时间内迅速破胶的添加剂技术.该技术所应用的胶囊产品是压裂措施中的新型添加剂,国内该类产品的制备工艺有锅包法、流化法等.通过优化胶囊破胶剂产品的配方,改进其制备工艺,采用侧喷流化制粒并初次包裹、底喷流化二次包裹的方法,提高了胶囊破胶剂产品的性能,降低了其生产成本.经现场应用,新型胶囊破胶剂的控释、缓释性能得到较好地发挥,其耐温可达90℃,大幅度地提高了胶囊过破胶技术在压裂工艺中的应用水平.