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41.
Assessing the role of basic control measures, antivirals and vaccine in curtailing pandemic influenza: scenarios for the US, UK and the Netherlands 总被引:1,自引:0,他引:1
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An increasing number of avian flu cases in humans, arising primarily from direct contact with poultry, in several regions of the world have prompted the urgency to develop pandemic preparedness plans worldwide. Leading recommendations in these plans include basic public health control measures for minimizing transmission in hospitals and communities, the use of antiviral drugs and vaccination. This paper presents a mathematical model for the evaluation of the pandemic flu preparedness plans of the United States (US), the United Kingdom (UK) and the Netherlands. The model is used to assess single and combined interventions. Using data from the US, we show that hospital and community transmission control measures alone can be highly effective in reducing the impact of a potential flu pandemic. We further show that while the use of antivirals alone could lead to very significant reductions in the burden of a pandemic, the combination of transmission control measures, antivirals and vaccine gives the most 'optimal' result. However, implementing such an optimal strategy at the onset of a pandemic may not be realistic. Thus, it is important to consider other plausible alternatives. An optimal preparedness plan is largely dependent on the availability of resources; hence, it is country-specific. We show that countries with limited antiviral stockpiles should emphasize their use therapeutically (rather than prophylactically). However, countries with large antiviral stockpiles can achieve greater reductions in disease burden by implementing them both prophylactically and therapeutically. This study promotes alternative strategies that may be feasible and attainable for the US, UK and the Netherlands. It emphasizes the role of hospital and community transmission control measures in addition to the timely administration of antiviral treatment in reducing the burden of a flu pandemic. The latter is consistent with the preparedness plans of the UK and the Netherlands. Our results indicate that for low efficacy and coverage levels of antivirals and vaccine, the use of a vaccine leads to the greatest reduction in morbidity and mortality compared with the singular use of antivirals. However, as these efficacy and coverage levels are increased, the use of antivirals is more effective. 相似文献
42.
一种基于混沌的随机数发生器设计及其IC实现 总被引:1,自引:1,他引:0
在密码学、仿真学以及集成电路测试等许多领域 ,随机数起着重要的作用。在密码学中 ,通常要求所使用的随机数具有不可预测性。基于混沌现象 ,使用开关电容技术 ,用集成电路实现了一种硬件随机数发生器。测试结果表明 ,其产生的序列具有不可预测性 ,可以满足密码学的应用要求。 相似文献
43.
开发有线电视收费管理系统需注意的问题 总被引:1,自引:1,他引:0
分析有线电视业务及用户管理中出现的问题与解决办法,为系统的开发建立数据模型,以确保有线电视网络公司和用户的利益。 相似文献
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46.
介绍了XC型车号自动识别系统的工作原理及在轨道衡的应用,解决了长期以来轨道衡路用车车号和自重依靠人工抄录易出错及劳动强度大的问题。 相似文献
47.
Swelling degrees of poly(N-vinyl-2-pyrrolidone) (PVP) gel were measured in aqueous salt solutions and in water/organic solvent mixtures to find marked ion- and solvent-specificities. In order to investigate any correlation of those specificities with hydration or solvation of PVP, IR spectra band of the CO group was monitored by means of ATR method both for PVP gel and the relevant solution systems. Dependence of the peak frequency on the swelling ratio suggested that hydration of PVP carbonyl group in deswollen gel systems is different from that in the corresponding solution systems. In the solution systems, PVP carbonyl band showed a high-wavenumber shift for deswollen systems, which can be well correlated with changes in water proton charge through ionic hydration and with Gutmann's acceptor number of organic solvents. In the deswollen gel systems, the CO band showed a low-wavenumber shift, suggesting a strong hydration or doubly hydrated state. This unexpected behavior was interpreted by assuming an intermolecular hydrogen bond of two carbonyl groups intermediated by water molecules. 相似文献
48.
车号定位识别与可信度估计 总被引:2,自引:0,他引:2
以车号的定位与识别为例,应用行投影法对车号图片进行倾斜行定位,证明了模拟与场景的二维互相关系数近拟等于一维投影互相关系数,在此基础上提列投影法快速行扫描识别算法及相应的可信度估计方法,这种方法对于室外拍摄的有复杂背景,光照变化,字体微倾,字符排列疏密不均及噪声干扰的车牌图像具有很好的识别效果。 相似文献
49.
由于来自催化裂化装置的烷基化原料中所含有的丁二烯在烷基化反应中可生成重质油,使产品干点上升,辛烷值下降,并使酸耗增加.针对这种状况,齐鲁石化公司研究院和胜利炼油厂联合开发了QSH-01烷基化原料预加氢催化剂及其相应的工艺技术,来脱除原料中丁二烯.笔者对该工艺技术及其应用作了阐述,并对该技术的应用前景作出分析. 相似文献
50.
YAG:Ce Phosphors for WLED via Nano-Pesudoboehmite Sol-Gel Route 总被引:5,自引:0,他引:5
The sub-micron sized YAG : Ce phosphors were synthesized via a modified sol-gel method by peptizing nano-pesudoboehmite particulate. It is found that YAG phase from the dried gel powders appears at 1000 ℃ then the pure YAG phase exists at a relatively lower sintering temperature of 1400 ℃. The smaller sizes of phosphors in the ranges of 1 - 3 μm are obtained due to the contribution of seeding effects of nano-sized alumina particles to strengthen each step of the processes. Both the excitation and emission spectra of photoluminescence of the phosphor obtained at 1400 ℃ meet well with the spectroscopic requirements of the WLED phosphors. 相似文献