The Observation of Lomer-Cottrell Dislocations in Boron-diffused (111) Silicon by Berg-Barrett Skew Reflections†

Skew reflections wore employed to obtain a series of Berg—Barrett x-ray diffraction micrographs of shallow boron-diffused layers in (111) silicon. Diffusion-induced dislocations with 〈110〉 singular lines were observed, and their Burgers vectors, distribution and relative density were determined. The dislocations are Lomer-Cottrell locks. Their distribution indicates that the two-step deposition-and-drive diffusion process, of the type commonly used in integrated-circuit fabrication, produces a solute profile which deviates considerably from the assumed Gaussian form. It is demonstrated that the images recorded on the x-ray micrographs represent well-defined dislocation aggregates rather than individual dislocations.     

癌症“细菌疗法”的研究进展

目前的癌症治疗方法毒性大,定位性差且不能有效穿透癌细胞,因此治疗效果有限。基因工程细菌能够准确的定位于所有肿瘤区域而克服这些缺点,其转运机理包括特殊的趋化性,优先生长和厌氧生长。目前的研究进展包括细胞毒素释放的时序控制,前体药物的酶激活和生理活性物质的分泌。经基因改造的细菌可表达肿瘤坏死因子-α,缺氧诱导因子-1-α,抗体,白细胞介素-2和胞嘧啶脱氨酶等,这些代谢产物具有增强肿瘤治疗效果的作用。本文对癌症＂细菌疗法＂的相关研究进行综述。     

使用FPGA进行网络入侵监测

FPGA技术已经被广泛用于实时网络入侵监测.一个称为BV-TCAM的数据包分类体系,它是用来实现以FPGA为基础的网络入侵监测系统(NIDS).这个分类器每秒钟报出网络连接中的多个以比特单位的匹配,它结合了三重内容可设定地址的存储(TCAM)和比特向量算法(BV).     

转炉OG泥回收的新方法

通过巴西BV钢厂烧结工艺设计,对OG泥回收提出了一种新的干式利用方法。即将OG泥、高炉返矿、钢铁厂粉尘三种杂料按一定比例配合,在搅拌机中进行混匀,制成小球后配入烧结混合料。该工艺在投产后效果良好。     

一种积累型沟道的半超结结构绝缘栅双极型晶体管

A high performance trench insulated gate bipolar transistor which combines a semi-superjunction struc- ture and an accumulation channel （sSJTAC-IGBT） is proposed for the first time. Compared with the TAC-IGBT, the new device not only retains the advantages of the accumulation channel, but also obtains a larger breakdown voltage （BV）, a faster turn-off speed and a smaller saturation current level while keeping the on-state voltage drop lower as the TAC-IGBT does as well. Therefore, the new structure enlarges the short circuit safe operating area （SCSOA） and reduces the energy loss during the turn-off process.     

Interactions between Lactobacillus crispatus and Bacterial Vaginosis (BV)-Associated Bacterial Species in Initial Attachment and Biofilm Formation

Certain anaerobic bacterial species tend to predominate the vaginal flora during bacterial vaginosis (BV), with Gardnerella vaginalis being the most common. However, the exact role of G. vaginalis in BV has not yet been determined. The main goal of this study was to test the hypothesis that G. vaginalis is an early colonizer, paving the way for intermediate (e.g., Fusobacterium nucleatum) and late colonizers (e.g., Prevotella bivia). Theoretically, in order to function as an early colonizer, species would need to be able to adhere to vaginal epithelium, even in the presence of vaginal lactobacilli. Therefore, we quantified adherence of G. vaginalis and other BV-associated bacteria to an inert surface pre-coated with Lactobacillus crispatus using a new Peptide Nucleic Acid (PNA) Fluorescence In Situ Hybridization (FISH) methodology. We found that G. vaginalis had the greatest capacity to adhere in the presence of L. crispatus. Theoretically, an early colonizer would contribute to the adherence and/or growth of additional species, so we next quantified the effect of G. vaginalis biofilms on the adherence and growth of other BV-associated species by quantitative Polymerase Chain Reaction (qPCR) technique. Interestingly, G. vaginalis derived a growth benefit from the addition of a second species, regardless of the species. Conversely, G. vaginalis biofilms enhanced the growth of P. bivia, and to a minor extent of F. nucleatum. These results contribute to our understanding of BV biofilm formation and the progression of the disorder.     

罗801区块油藏环境厌氧微生物链的形成及其对微生物驱采收率的影响

概述了油藏厌氧生境中的厌氧微生物链并给出图解式。根据胜利罗家油田罗 80 1区块微生物驱油试验中的监测数据 ,注入驱油菌BS、FM及营养物质后 ,试验区产出水中水解菌、产氢产乙酸菌、反硝化菌、产甲烷菌、同型产甲烷菌的总菌数由 10 0 ～ 10 7个 /mL增加到 10 3 ～ 10 4个 /mL ,乙酸根浓度由 2 1.8mg/L增加到 4 0 0mg/L以上。由此推断 ,注入的水解类菌BS和FM及营养物质激发了油藏中各类厌氧菌的活性 ,通过各类菌群的繁殖代谢 ,形成了新的厌氧微生物链。该微生物链的首端为注入油藏的和油藏中原有的水解菌 ,以产氢产乙酸菌、反硝化菌、同型产乙酸菌为中间阶段 ,末端为产甲烷菌 ,给出了该厌氧微生物链的图解式 ,讨论了链中一些微生物的生长代谢、相互作用及驱油作用。介绍了罗 80 1区块微生物驱油试验的结果 :产油量递减率控制在 5 %以内 ,年产油量稳定在4 .4× 10 4t以上 ,平均年增产油量 1.2 7× 10 4t ,采收率已提高 2 .11% ,预计最终可提高采收率 5 .6 6 %。图 7表 1参5。     

In vitro study of antioxidant capacity and antibacterial activity on oral anaerobes of a grape seed extract

Grape seeds are considered rich sources of polyphenolic compounds that show antioxidant or antimicrobial effects. The aim of the present work was to investigate the effect of a grape seed extract (GSE) on two oral anaerobes closely associated with periodontal diseases and its antioxidant action.     

大规格50BV30盘条麻面缺陷成因分析及控制措施

为符合当前节约、绿色的生产发展,用户在大规格50BV30盘条的加工中采用轻拉拔工艺,因此对盘条的表面质量提出了较高的要求。针对永钢大规格50BV30盘条表面麻面缺陷问题,分析了该缺陷对拉拔加工的影响,统计得到麻面缺陷深度需要控制在30μm以内才能满足客户的使用要求,而当前生产的盘条麻面缺陷平均深度达70μm。为此,从轧辊表面质量及氧化铁皮压入两个方面分析了对麻面缺陷的影响。结果表明：轧槽过钢量是影响轧辊表面质量的主要因素之一,从而影响盘条表面麻面缺陷。随着轧槽过钢量的增加,大规格50BV30盘条表面麻点缺陷越发严重,因此实际生产中,粗、中轧轧槽过钢量不应超过600 t。轧件表面氧化铁皮压入,尤其是次生氧化铁皮压入轧件基体后,盘条表面麻点缺陷数量和深度明显增加,将轧前高压水除鳞压力由10 MPa提升至19 MPa,并在终轧前增加二次除鳞工艺,大规格50BV30盘条麻面缺陷改善明显。采用上述措施,麻面缺陷平均深度由70μm降至30μm以下,满足了下游客户的加工使用要求。     

The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain

Interleukin (IL)-22 is a potent mediator of inflammatory responses. The IL-22 receptor consists of the IL-22Rα and IL-10Rβ subunits. Previous studies have shown that IL-22Rα expression is restricted to non-hematopoietic cells in the skin, pancreas, intestine, liver, lung, and kidney. Although IL-22 is involved in the development of inflammatory responses, there have been no reports of its role in brain inflammation. Here, we used RT-PCR, Western blotting, flow cytometry, immunohistochemical, and microarray analyses to examine the role of IL-22 and expression of IL-22Rα in the brain, using the microglial cell line, hippocampal neuronal cell line, and inflamed mouse brain tissue. Treatment of BV2 and HT22 cells with recombinant IL-22 increased the expression levels of the pro-inflammatory cytokines IL-6 and TNF-α, as well as cyclooxygenase (COX)-2 and prostaglandin E2. We also found that the JNK and STAT3 signaling pathways play an important role in IL-22-mediated increases in inflammatory mediators. Microarray analyses revealed upregulated expression of inflammation-related genes in IL-22-treated HT22 cells. Finally, we found that IL-22Rα is spontaneously expressed in the brain and is upregulated in inflamed mouse brain. Overall, our results demonstrate that interaction of IL-22 with IL-22Rα plays a role in the development of inflammatory responses in the brain.