新型凉味剂N,2,3-三甲基-2-异丙基丁酰胺（WS-23）的合成

新型凉味剂N,2,3-三甲基-2-异丙基丁酰胺(即WS-23)以丙腈为原料,经烷基化、酰胺化两步合成,总收率为73.2%.中间体2,3-二甲基-2-异丙基丁腈及终产品N,2,3-三甲基-2-异丙基丁酰胺通过红外光谱分析确证其与目标产品结构一致.     

基于GSM短信息的智能温度监控系统的开发

介绍了一种以PIC系列单片机或个人电脑为控制核心的、基于GSM短信息的温度监控系统的硬件与软件设计。该系统采用了不同于一般TEXT或PDU的短信格式,具有更强的通用性和更好的可识别性。     

The effect of frequent hemodialysis on matrix metalloproteinases,their tissue inhibitors,and FGF23: Implications for blood pressure and left ventricular mass modification in the Frequent Hemodialysis Network trials

Background: Frequent hemodialysis modifies serum phosphorus, blood pressure, and left ventricular mass (LVM). We ascertained whether frequent hemodialysis is associated with specific changes in biomarker profile among patients enrolled in the frequent hemodialysis network (FHN) trials. Methods: This was a post hoc analysis of biomarkers among patients enrolled to the FHN trials. In particular, we hypothesized that frequent hemodialysis is associated with changes in a specific set of biomarkers which are linked with changes in blood pressure or LVM. Results: Among 332 randomized patients, 243 had biomarker data available. Of these, 124 patients were assigned to 3‐times‐a‐week hemodialysis (94 [Daily Trial] and 30 [Nocturnal Trial]) and 119 patients were assigned to 6‐times‐a‐week hemodialysis (87 [Daily Trial] and 32 [Nocturnal Trial]). Frequent hemodialysis lowered phosphate, blood pressures, LVM, log fibroblast growth factor (FGF)23, and tissue inhibitors of metalloproteinase (TIMP)—2 levels. The fall in phosphate was associated with changes in FGF23 (r = 0.48, P < 0.001) [Daily Trial] and (r = 0.55, P < 0.001) [Nocturnal Trial]) and tended to be associated with changes in systolic blood pressure (r = 0.18, P = 0.057) [Daily Trial] and (r = 0.31, P = 0.04) [Nocturnal Trial]. Within the Daily Trial, changes in MMP2 (r = 0.20, P = 0.034) were associated with changes in LVM. In the Nocturnal Trial, changes in TIMP‐1 (r = 0.37, P = 0.029) and MMP 9 (r = ?0.38, P = 0.01) were associated with LVM changes. MMP2 changes were associated with changes in systolic blood pressure. Conclusions: Reduction of serum phosphate by frequent hemodialysis may modulate FGF23 levels and systolic blood pressure. Markers of matrix turnover are associated with LVM changes. Frequent hemodialysis may affect pathological mediators of chronic kidney disease‐mineral bone‐metabolism disorder.     

感潮河段交汇区水流特性数值模拟 --以宁波三江口为例

河流交汇为城市的发展提供了便利,对区域防洪、航运及河道演变影响重大。针对感潮河段交汇区域特有的非恒定往复流条件,以宁波三江口为例,运用Delft-3D建立二维水动力数学模型。基于实测水文和地形资料,引入四种评估参数对模型进行了率定与验证。重点分析了洪、枯两季涨、落急时刻,交汇区流速分布及水面形态等水流特性。结果表明:涨潮时,交汇区流场可类比分叉水流;落潮时,则为交汇水流;交汇区顶点及左支入汇侧下游存在两个低流速区,并可形成分离区;汇流区流速整体呈落潮大于涨潮的趋势,洪、枯季间最大流速相近。此外,涨、落急时刻典型特征断面水面呈单一横比降,且落急时刻比降明显大于涨急时刻;落急时,交汇口水面呈混合层附近高,两侧低的"马鞍形"分布。     

国产T23钢高温时效时组织和力学性能的研究

采用光学显微镜、扫描电镜、透射电镜观察和拉伸、冲击试验等方法,研究了国产T23钢在600 ℃时效时的组织变化和力学性能.结果表明,T23钢在600 ℃时效时随着时效时间的延长,T23钢中M23C6型碳化物不断粗化,粒状贝氏体形貌逐渐退化.时效时间较短时,主要是M23C6型碳化物粗化引起T23钢力学性能下降;时效时间较长时,主要是粒状贝氏体形貌的变化导致T23钢力学性能下降,同时,M23C6的球化及其向M6C的转变、亚晶的形成和W、Mo固溶强化的降低加快了T23钢力学性能的下降.     

30 years of British utility regulation: Developing country experience and outlook

This article examines the impact the UK regulatory model has had in developing and transition countries in the three decades since its inception. It presents data linked to three key features of the model, namely independent regulatory institutions; focus on competition; and greater efficiency in service delivery through incentive-based regulation. The difficulty of formulating statements valid for a very diverse set of countries is acknowledged. Nevertheless, the article argues that despite of the rapid spread of regulatory agencies across the world, the UK regulatory model has been only partially successful in middle- and low-income countries. The main explanation offered is that the ‘de-politization’ of regulatory institutions is more challenging to achieve in a context of below cost-recovery tariffs and continued state-ownership of utilities. But improving the technical soundness of decision making and introducing accountability for operators are key tasks that regulators can address even if the gap to the UK ideal remains in a number of countries.     

The British utility regulation model: Its recent history and future prospects

This paper considers the evolution of the British model of independent utility regulation from the publication of the 1983 Littlechild Report on telecom regulation. Over the last ten years, the model has faced some threats to its pro-competition emphasis, notably in energy regulation and particularly in electricity. These threats have arisen since 2008 and the onset of the Great Recession. However, with the partial exception of energy, challenges to the independence of regulators and to the role of competition have not been acute. The model seems to have generally been able successfully to meet the challenges faced and, relative to other countries, remains intact, if less distinctive. The main continuing issue is how best to handle repeat price-setting regulatory reviews where new initiatives have been tried but have not as yet reached a settled framework within which to handle the underlying strategic gaming problems.     

The analysis for morphological evolution and crystallography of degenerate pearlite in 100Mn13 steel

During approximate 773 K aging treatment of 100Mn13 steel, degenerate pearlite will occur and evolve into lamellar pearlite during growth process. The microstructures of degenerate pearlite and its evolutionary lamellar pearlite are observed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The results show that after 748 K, 773 K and 798 K aging, degenerate pearlites occur at grain boundary. At growth front of degenerate pearlite forming at 773 K and 798 K, pearlite presents a morphology of short lamellae of carbide and ferrite, indicating a trend of developing into lamellar pearlite. The higher the temperature is, the more obvious the trend is, and even a conventional lamellar pearlite has developed. However, there is no morphological evolution for degenerate pearlite forming at 748 K aging. Besides, the constituents of degenerate pearlite is identified as M₂₃C₆ and ferrite, and Kurdjumov-Sachs orientation relationship exists between them, (01 )_α//( 1 )_M23C6, [111]_α//[110]_M23C6. This orientation relationship maintains in morphological evolution from degenerate pearlite to lamellar pearlite.     

音频编解码器TLV320AIC23与CPLD接口设计

介绍了音频编解码器TLV320AIC23芯片的功能,相关寄存器的设置和采样率的选取,通过分析提出了用CPLD代替DSP,进行TLV320AIC23与CPLD的接口设计,实现数字语音设备学生机终端的A/D及D/A转换。