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31.
Shiang Suo Huang Lan Hui Chih Chia Hsien Lin Long Y. Chiang Tadahiko Mashino Masataka Mochizuki Kensuke Okuda Takasi Hirota Ming-Cheng Tsai Ming Cheng Tsai 《Fullerenes, Nanotubes and Carbon Nanostructures》2001,9(3):375-395
The effects of hexasulfobutylated (FC4S), the fullerene derivative on the contraction of smooth muscle were tested pharmacologically on the circular muscle of stomach of guinea pigs. The effects of monomalonic acid C60 (MMA C60) on the same preparations were compared. The effects of those compounds on the taenia coli, portal vein and vas deferens of guinea pigs were also tested. The FC4S did, while MMA C60 did not elicit contracture of the circular muscle of stomach and taenia coli. Both FC4S and MMA C60 did not elicit contraction on the portal vein and on the vas deferens of the guinea pig. Prazosin (0.5 μM) or propranolol (0.5 μM) did not alter the FC4S elicit contracture of the circular muscle of stomach. However, atropine (0.01, 0.1 and 1 μM), tetrodotoxin (0.1 μM) or low calcium medium decreased reversibly the FC4S elicited contracture of the circular muscle of stomach. The effect of FC4S on the contracture of the gastric muscles was also tested using various muscarinic receptor subtype antagonists. 4-DAMP (1 μM), muscarinic M3 receptor antagonist, and tropicamide (1 μM), muscarinic M4 receptor antagonist, did not alter the contracture elicited by FC4S. Pirenzepine (0.1 μM), muscarinic M1 receptor antagonist, and methoctramine (0.25 μM), muscarinic M2 receptor antagonist, significantly decreased the FC4S elicited contracture of the circular muscle. Atropine (1 μM) or tetrodotoxin (0.1 μM) completely blocked the FC4S elicited contracture of the circular muscle of stomach. It is concluded that FC4S elicited contracture of the circular muscle of stomach. The effect may be due to FC4S acts on the cholinergic cells existed in the gastric muscle and indirectly activating the tetrodotoxin dependent releasing of the transmitters from the cells, then, activating the muscarinice M1, M2 receptors in the muscle eliciting the contractures. 相似文献
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Cellulase was immobilized directly on methyl methacrylate‐glycidyl methacrylate copolymer (MMA‐co‐GMA) and methyl methacrylate‐2‐hydroxy ethyl methacrylate copolymer (MMA‐co‐HEMA) by covalent attachment and crosslinking methods. The properties of the immobilized cellulase were investigated and compared with those of the free one. For the assays carried out through crosslinking method at 25°C and pH 7, the retained activities were found to be 91.92% and 74.63%, respectively, for MMA‐co‐GMA and MMA‐co‐HEMA crosslinked with 0.1% of 1‐cyclohexyl‐3‐(2‐morpholino‐ethyl) carbodiimide metho‐p‐toluenesulfonate (CMCT), respectively. The immobilized cellulase had better stability and higher retained activities with respect to pH, temperature, and storage stability than the free one. In the repeated use experiments, the immobilized cellulase using (MMA‐co‐GMA)‐CMCT (0.1%) and (MMA‐co‐HEMA)‐CMCT (0.1%) did not change after 10 and eight times of repeated use and maintained 67% and 62% from their original activities after 25 times, respectively. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 相似文献
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为有效地抑制样本随机性的影响,改善MIMO雷达的检测性能,通过分析已有的基于迭代最小均方误差(RMMSE)估计和迭代最大化输出信噪比(RMSNR)准则的APC技术,指出样本随机性是影响以迭代APC技术为基础的检验统计量检测性能的重要因素。提出基于RMMSE和RMSNR的多通道多脉冲平均APC(MMA-APC)技术,并以此为基础构造检验统计量。基于自适应脉冲压缩(APC)技术研究了空间分集MIMO雷达相参脉冲串条件下的目标检测问题。 相似文献
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为了提高交通事故现场防护水平和预防二次事故,利用C8051F020单片机以及MMA7260,MicroMag2等传感器设计了一种设备,对车辆入侵进行检测,迅速有效地判断车辆是否侵入防护现场,根据检测结果实现报警。 相似文献
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Poly(GMA/MMA) beads were synthesized from glycidyl methacrylate (GMA) and methyl methacrylate (MMA) in the presence of a cross‐linker (i.e. ethyleneglycol dimethacrylate) (EGDMA) via suspension polymerization. The epoxy groups of the poly(GMA/MMA) beads were converted into amino groups with either ammonia or 1,6‐diaminohexane (i.e. spacer‐arm). An L ‐histidine ligand was then covalently immobilized on the aminated (poly(GMA/MMA)‐AH) and/or the spacer‐arm attached (poly(GMA/MMA)‐SAH) beads using glutaric dialdehyde as a coupling agent. Both affinity adsorbents were used in human serum albumin (HSA) adsorption/desorption studies under defined pH, ionic strength or temperature conditions in a batch reactor. The spacer‐arm attached affinity adsorbent resulted in an increase in the adsorption capacity to HSA when compared to the aminated counterpart (i.e. poly(GMA/MMA)‐AH). The maximum adsorption capacities of the affinity adsorbents were found to be significantly high, i.e. 43.7 and 80.2 mg g?1 (of the beads), while the affinity constants, evaluated by the Langmuir model, were 3.96 × 10?7 and 9.53 × 10?7 mol L?1 for poly(GMA/MMA)‐AH and poly(GMA/MMA)‐SAH, respectively. The adsorption capacities of the affinity adsorbents were decreased for HSA by increasing the ionic strength, adjusted with NaCl. The adsorption kinetics of HSA were analysed by using pseudo‐first and pseudo‐second‐order equations. The second‐order equation fitted well with the experimental data. Copyright © 2005 Society of Chemical Industry 相似文献
37.
NEW HMM ALGORITHM FOR TOPOLOGY OPTIMIZATION 总被引:1,自引:0,他引:1
Zuo KongtianZhao YudongDepartment of Automotive Engineering Tsinghua University Beijing ChinaChen LipingZhong YifangSchool of Mechanical Engineering Huazhong University of Scienceand Technology Wuhan ChinaHuang YuyingDepartment of Mechanics Huazhong University of Scienceand Technology Wuhan China 《机械工程学报(英文版)》2005,18(3):346-350
0 INTRODUCTIONTwo types of algorithms are currently widely used instructure optimization. The first one is the optimization criteria(OC) method. The OC method can be understood directly, but it isdifficult to deduce different types of optimization criteri… 相似文献
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汽车安全气囊加速计MMA2204D及其应用 总被引:1,自引:0,他引:1
介绍了低功耗、高精度,并带有集成信号放大、信号处理、低通滤波和补偿的硅电容加速度计MMA2204D的主要性能,给出了将MMA2204D应用于汽车安全气囊的应用方法。 相似文献
40.
本文的主要目的是基于信息融合的方法设计出一套能准确辨识出驾驶行为的系统.本系统使用六轴加速度计采集加速度信息,通过多尺度多重分形(MMA)算法(首次将该算法用作特征提取的方法)从加速度信号中提取出可反映不同驾驶行为的波动特征.并采集电动汽车的OBD接口获取的包括速度、功率、电流等车载OBD信息并提取特征.分别通过随机森林(RF)算法对驾驶员的驾驶行为进行辨识.提出一种新的信息融合的方法,采用该方法对加速度信息和OBD信息进行融合,发现信息融合的方法可以更有效的辨识出电动汽车的驾驶行为. 相似文献