复合水凝胶角膜接触镜材料的设计与合成

通过高聚物分子设计的方法,以吸水倍率低的HEMA水凝胶为基体材料,以吸水倍率高的PVPP(交联NVP)颗粒为分散相,制备出了具有明显相界面层的复合水凝胶角膜接触镜材料.通过大量实验表明其制备工艺为:PVPP颗粒与单体HEMA的质量比为10:90,致孔剂PEG400为35%(wt,相对于总反应物),BPO为0.4%(wt,相对于反应单体),反应混合物混合均匀后立即压片、放入温度为75℃的水浴中,反应12h.为下一步研究具有药物缓释功能的、可重复利用的角膜接触镜奠定了基础.     

交联PVP对茶多酚的吸附作用

采用自制交联PVP处理铁观音茶叶水 ,在交联度为 0 .5 %、用量为 7g/L、30℃下处理 30min时 ,茶多酚的吸附率为 66 83%。分析吸附机理认为 ,交联PVP上的活性吸附中心与茶多酚形成氢键吸附。     

HEMA-NVP共聚物表面性能研究

室温下,以质量分数为0.2%的2-羟基-甲基苯基丙烷-1-酮(1173)为引发剂,0.5%的二乙二醇甲基丙烯酸酯(EGDMA)为交联剂,在紫外光照下合成了甲基丙烯酸2-羟基乙酯(HEMA)-N-乙烯吡咯烷酮(NVP)二元共聚物水凝胶.探讨了共聚物表面的润湿性、脱水性及对牛血清蛋白(BSA)的吸附性.试验表明,材料薄膜表面接触角随着NVP含量增大及接触时间的延长而减小;BSA通过物理作用吸附于水凝胶薄膜表面,BSA吸附量随时间延长及吸附液初始浓度升高而增大;随着共聚物中NVP含量的增大,BSA吸附量增大,而释放量减小;脱水试验表明水凝胶薄膜的脱水速率随NVP及交联剂含量的增大而减小.     

Iodinated P(MMA‐NVP): an efficient matrix for disinfection of water

Polymethyl methacrylate‐N‐vinyl‐2‐pyrrolidone P(MMA‐NVP) copolymer was synthesized in an inert atmosphere by bulk polymerization using azobis‐isobutyronitrile (AIBN) as initiator. The copolymer was crushed, and ground to a defined particle size and iodinated. The iodinated copolymer matrix was washed thoroughly in a suitable solvent so as to remove any residual iodine and characterized using solubility, swelling, viscosity, FT‐IR, and ¹H‐NMR studies. The iodinated copolymer was then packed in a refill cartridge specially designed for the purpose. The release of iodide ions from the iodinated matrix was measured in a continuous flow system by directly attaching the cartridge to the water tap and adjusting the flow rate. The water samples were collected at regular intervals and estimated for the concentration of iodide ions using an iodide ion selective electrode. The antimicrobial activity of the copolymer was estimated against bacterial (both Gram‐positive and ‐negative) and fungal species using the zone of inhibition technique. In addition, efficacy of the iodinated copolymer against a variety of microbes was established by inoculating a microbial culture in the water reservoir and measuring the rate of survival of microbes after passing through the copolymer‐filled column. The iodinated copolymer was found to be effective against a variety of microbes and remained so completely until 5000 L of water had passed. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 76: 1109–1116, 2000     

甲基丙烯酸-2-羟基乙酯-co-N-乙烯-2-吡咯烷酮水凝胶结构及溶胀行为研究

为探讨甲基丙烯酸-2-羟基乙酯（HEMA）-co-N-乙烯-2-吡咯烷酮（NVP）共聚物水凝胶薄膜的溶胀性能,以2-羟基-甲基苯基丙烷-1-酮（1173）为光引发剂,二乙二醇甲基丙烯酸酯（DEGDMA）为交联剂,用紫外灯在室温下合成不同配比的HEMA-co-NVP共聚物薄膜。FTIR证实了共聚反应,热重（TG）测试显示薄膜结构中易分解的组分含量随着单体NVP含量的增加而增加。共聚物溶胀实验结果表明：随着交联剂含量的增加,水凝胶平衡溶胀率（EWC）下降;随着单体NVP含量的增加,材料的EWC上升,共聚水凝胶的溶胀过程趋于Case-Ⅲ型;随着温度的升高,材料的EWC降低,溶胀过程趋向Fick溶胀。     

AM/AMPS/第三单体三元共聚物耐温抗盐驱油体系的合成与性能

以丙烯酰胺(AM)和2-丙烯酰胺基-2-甲基丙磺酸(AMPS)为基本单体,再引入具有不同结构或基团的第三单体:N,N-二甲基丙烯酰胺(DMAM),N-乙烯基-2-吡咯烷酮(NVP)和十二烷基苯磺酸钠(DBS),通过水溶液聚合法合成了3种耐温抗盐三元共聚物(AM/AMPS/第三单体),对比研究3种三元共聚物及AM/AMP...     

N-异丙基丙烯酰胺对软接触镜材料性能的影响

以0.2%的2-羟基-甲基苯基丙烷-1-酮(1173)为引发剂,0.5%的二乙二醇甲基丙烯酸酯(EGDM A)为交联剂,常温下用紫外灯合成了N-异丙基丙烯酰胺(N IPAm)/甲基丙烯酸2-羟基乙酯(HEM A)/N-乙烯吡咯烷酮(NVP)三元共聚物;与相同条件下合成的HEM A/NVP共聚物进行了试验对比。凝胶在水中的溶胀实验证明,含N IPAm的三元共聚物溶胀率对温度的敏感性强于HEM A-NVP共聚物;傅立叶红外光谱与热重测试显示了两种材料的结构差异。     

水凝胶接触镜材料的溶胀行为与脱水行为

INTRODUCTION Most contact lens are made by organic hydrogel, and thepermeability of hydrogel to oxygen is critical because comea requiresoxygen for metabolism of its principal nutrient.     

交联性聚乙烯基吡咯烷酮PVPP的制法及其应用

阐述了交联性聚乙烯基吡咯烷酮的制备方法,以及其在医药行业和其他行业的用途。     

新型聚硼硅氮烷杂化树脂的制备研究

以聚硼硅氮烷（PSNB）、N-乙烯基吡咯烷酮（NVP）为原料,由过氧化二异丙苯（DCP）引发自由基共聚合反应,制备了聚硼硅氮烷（PSNB/NVP）杂化树脂。采用差示扫描量热仪、热失重仪、红外光谱仪、平板流变仪等对杂化树脂的热性能、固化过程、流变行为等进行测试。结果表明,随着PSNB与NVP的质量比的提高,杂化树脂的热稳定性升高,PSNB与NVP质量比为20/80的杂化树脂在热质量损失率达到为5%时的温度较聚N-乙烯基吡咯烷酮提高近200℃;由杂化树脂高温裂解可得到硅硼碳氮多孔陶瓷,其孔尺寸及分布极不均匀。