现代商业理念与“非遗”旅游开发中的难题——以大坝高装开发面临的资源成本难题为例

国家级“非遗”大坝高装的旅游开发,面临着成本高、所需资源短缺的难题,传统的小生产模式及其思想的限制是重要原因。在价值工程、外包等现代商业理念指导下整合其他“非遗”资源进行合作开发,可以较好地克服前述难题。合作开发会使“非遗”旅游开发中的各方之间的矛盾更为复杂,最佳协调方式是市场交易。但是,市场主体之间的自发交易成本过高。根据交易成本理论可找到降低成本的方式,即在政府部门主导下组建公司制经济实体作为合作开发平台,利用公司治理机制协调各利益相关者。     

Tissue Engineering and Regenerative Medicine in Pediatric Urology: Urethral and Urinary Bladder Reconstruction

In the case of pediatric urology there are several congenital conditions, such as hypospadias and neurogenic bladder, which affect, respectively, the urethra and the urinary bladder. In fact, the gold standard consists of a urethroplasty procedure in the case of urethral malformations and enterocystoplasty in the case of urinary bladder disorders. However, both surgical procedures are associated with severe complications, such as fistulas, urethral strictures, and dehiscence of the repair or recurrence of chordee in the case of urethroplasty, and metabolic disturbances, stone formation, urine leakage, and chronic infections in the case of enterocystoplasty. With the aim of overcoming the issue related to the lack of sufficient and appropriate autologous tissue, increasing attention has been focused on tissue engineering. In this review, both the urethral and the urinary bladder reconstruction strategies were summarized, focusing on pediatric applications and evaluating all the biomaterials tested in both animal models and patients. Particular attention was paid to the capability for tissue regeneration in dependence on the eventual presence of seeded cell and growth factor combinations in several types of scaffolds. Moreover, the main critical features needed for urinary tissue engineering have been highlighted and specifically focused on for pediatric application.     

控制爆破技术在井下煤仓工程中的综合应用

义马煤业集团义络煤业公司在水平延深中,根据煤仓工程的特点,综合应用控制爆破技术解决三水平施工与二水平生产的矛盾,取得了较好的施工效果。     

采用起重机吊装桥梁工程的施工方法

采用起重机吊装预制梁,具有施工机具简单、易于操作、成本低、工期短、质量安全易于保证等优点。对于施工操作场地开阔、道路交通方便的中小桥梁工程,采用起重机吊装是一种较好的施工方法。     

抛物线理论多跨索道设计模型

在完善和充实抛物线理论的基础上,系统地提出抛物线理论多跨索道设计。该设计模型包括承载索的设计计算与选型、货物运输方式方法的确定、工作索及绞盘机的选择。为工程索道的安装架设提供可靠的技术参数,能确保索道安全生产,方便管理,提高工效和经济效益,延长使用寿命。     

化工原理及其实验教学改革

为了适应化学工业新技术日新月异的发展,根据化工原理及化工原理实验课程的特点以及化工学科今后的发展趋势对化工原理及其实验课程教学进行教学改革,以提高学生对该课程的理解、独立实验操作能力和实验创新能力,促进课程教学质量的提高。     

水利工程模型试验计算机测量与控制系统

采用计算机测量与控制系统应用于水利工程模型试验,设计应用先进的水流循环系统、电磁流量计、电子式电动调节阀、控制接口和软件组成计算机流量闭环自动控制系统;计算机测量与控制系统通过实际使用运行,证明达到了设计指标的要求,大大提高了模型试验测量与控制的精度和工作效率,缩短了模型试验周期,有利于水利工程研究成果质量和科研水平的提高.     

轿车悬架弹性橡胶衬套弯曲刚度的工程算法

在线性前提下,根据橡胶衬套径向刚度在线性范围内,找出了求解橡胶衬套弯曲刚度的工程算法,经过试验验证,具有工程使用价值.     

Polymerizable Skin Hydrogel for Full Thickness Wound Healing

The skin is the largest organ in the human body, comprising the main barrier against the environment. When the skin loses its integrity, it is critical to replace it to prevent water loss and the proliferation of opportunistic infections. For more than 40 years, tissue-engineered skin grafts have been based on the in vitro culture of keratinocytes over different scaffolds, requiring between 3 to 4 weeks of tissue culture before being used clinically. In this study, we describe the development of a polymerizable skin hydrogel consisting of keratinocytes and fibroblast entrapped within a fibrin scaffold. We histologically characterized the construct and evaluated its use on an in vivo wound healing model of skin damage. Our results indicate that the proposed methodology can be used to effectively regenerate skin wounds, avoiding the secondary in vitro culture steps and thus, shortening the time needed until transplantation in comparison with other bilayer skin models. This is achievable due to the instant polymerization of the keratinocytes and fibroblast combination that allows a direct application on the wound. We suggest that the polymerizable skin hydrogel is an inexpensive, easy and rapid treatment that could be transferred into clinical practice in order to improve the treatment of skin wounds.