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71.
Cyclic oxidation test is a fundamental method to assess lifetime of materials in high temperature environment.Cycle length or cyclic frequency is one important variable in cyclic oxidation testing.In present work,cyclic oxidation tests were performed on cast K38 alloys with 0 wt.%,0.1 wt.%,and 0.5 wt.% yttrium additions at 1 273 K respectively.Two cyclic frequencies were used to investigate the influence of cycle length (1 h vs.20 h) on the high temperature oxidation behavior of superalloy.The results showe... 相似文献
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在现有研究理论基础上,针对钢-混凝土后锚固连接钢材破坏时群锚弯剪承载力计算进行分析。采用椭圆型拉剪计算公式并假定所有锚栓均参与受剪,将群锚弯剪受力问题转化为受拉最大那排锚栓的拉剪承载力计算。进行了弯剪受力下的型钢-混凝土后锚固连接件静力和低周反复加载试验,锚固方式采用化学植筋。试验结果表明:受拉最大的钢筋首先达到屈服,且发生在整体锚固破坏前,仅钢筋周围局部混凝土在临近破坏时损坏,可以判断为钢材破坏,破坏前有明显的变形征兆,低周反复加载下后锚固连接承载力较相应的静力时低,建议抗震设计时取承载力折减系数0.8。通过对比分析,该文改进后的群锚弯剪受力方法的计算结果与试验数据吻合较好,可为工程设计提供参考。 相似文献
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采用电沉积方法在SnO2玻璃基底上制备了Co-Se化合物薄膜.研究了薄膜形成的电化学机理和电沉积工艺对薄膜组成与形貌的影响,并表征了薄膜的结构与光学性质.结果表明:Co2+受预沉积Se的表面诱导还原或直接与H2SeO3的六电子还原反应产物H2Se发生反应形成Co-Se化合物;沉积电位、沉积温度和pH值均显著影响电沉积Co-Se化合物薄膜的形貌与成分;在沉积电位为?0.5V(vs SCE)、沉积温度为50℃和pH值为2.0时可制备出表面致密平整且呈六方晶型结构的富硒CoSe薄膜,其光吸收系数达到1×105 cm?1,直接带隙宽度为(1.53±0.01)eV,接近单结太阳电池光吸收层材料的理论最佳值. 相似文献
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Abstract This study develops an analytical expression to describe the cyclic stress‐strain curve obtained from a series of fully‐reversed fatigue tests. A set of stress‐strain relationships is proposed to simulate the tensile branch of the stable hysteresis loop. The complete shape of the stable hysteresis loop is then constructed and the associated theoretical plastic work calculated by integrating the area within the enclosed curve. The theoretical plastic work is employed to predict the fatigue lives of the investigated materials on the basis of their respective stable plastic work per cyclelife curves. In this paper, the current mathematical derivations are based upon the endochronic theory of plasticity. The accuracy of the proposed set of stress‐strain relationships is verified by conducting fully‐reversed constant strain amplitude fatigue tests on AISI 316 and AISI 304 stainless steels. The experimental and simulation results are found to be in good agreement, hence confirming the accuracy of the proposed analytical stress‐strain relationships. Again, comparing the obverted and predicted fatigue lives, a good agreement is found between the two sets of results. 相似文献
78.
为了研究金属材料在疲劳载荷下的温度变化,采用红外热像系统对高周疲劳载荷下6061-T6铝合金的温度演化进行分析,用热像图对疲劳裂纹尖端的塑性区进行测量.结果显示,疲劳加载作用下,循环次数达到107次时6061-T6铝合金试样表面温度的变化分为四个阶段:初始温升阶段、温度缓降阶段、温度二次缓慢上升阶段和温度快速上升阶段.结合热弹性理论、铝合金塑性变形的微观机制分析并预测疲劳载荷下温度的演化和宏观裂纹扩展时裂纹尖端塑性区域大小.宏观裂纹开始扩展时,裂纹尖端的塑性区域可达3.6 mm2,红外热像仪测得结果为3.46 mm2,测试结果与理论结果吻合. 相似文献
79.
Sung-Min Hwang Youn-Yi Jo Cinder Faith Cohen Yong-Ho Kim Temugin Berta Chul-Kyu Park 《International journal of molecular sciences》2022,23(10)
The transient receptor potential vanilloid 1 (TRPV1) ion channel plays an important role in the peripheral nociceptive pathway. TRPV1 is a polymodal receptor that can be activated by multiple types of ligands and painful stimuli, such as noxious heat and protons, and contributes to various acute and chronic pain conditions. Therefore, TRPV1 is emerging as a novel therapeutic target for the treatment of various pain conditions. Notably, various peptides isolated from venomous animals potently and selectively control the activation and inhibition of TRPV1 by binding to its outer pore region. This review will focus on the mechanisms by which venom-derived peptides interact with this portion of TRPV1 to control receptor functions and how these mechanisms can drive the development of new types of analgesics. 相似文献
80.
Ying Yang Hui-Yun Chen Hua Hao Ke-Jian Wang 《International journal of molecular sciences》2022,23(10)
Scyreprocin is an antimicrobial peptide first identified in the mud crab Scylla paramamosain. Herein, we showed that its recombinant product (rScyreprocin) could significantly inhibit the growth of human lung cancer NCI-H460 cells (H460), but showed no cytotoxicity to human lung fibroblasts (HFL1). rScyreprocin was a membrane-active peptide that firstly induced the generation of reactive oxygen species (ROS) in H460, and led to endoplasmic reticulum stress and Ca2+ release, which resulted in mitochondrial dysfunction and subsequently activation of caspase-3 cascades, and ultimately led to apoptosis. The comprehensive results indicated that rScyreprocin exerted anticancer activity by disrupting cell membrane and inducing apoptosis. The in vivo efficacy test demonstrated that intratumoral injection of rScyreprocin significantly inhibited the growth of H460 xenografts, which was close to that of the cisplatin (inhibition rate: 69.94% vs. 80.76%). Therefore, rScyreprocin is expected to become a promising candidate for the treatment of lung cancer. 相似文献