聚乳酸纤维仿毛织物的染整工艺研究

由于聚乳酸纤维属于脂肪族聚酯,具有与PET相同疏水性及熔点较低、不耐高温和强碱的特点,因此采用低碱退浆、分散染料染色的染整工艺.文章介绍了实验材料聚乳酸纤维(PLA)仿毛机织物的烧毛、退浆、练漂、热定形、染色的工艺参数和染整加工中的加工要点及注意事项,着重分析了pH值、染色时间、染色温度对上染率的影响,并得出最佳的染色工艺参数:染色pH值5,温度110℃,时间35 min.     

葡萄糖氧化酶对小麦粉品质的影响研究

应用快速黏度分析仪(RVA)、动态流变仪、扫描电子显微镜(SEM)及液相色谱(LC)研究了葡萄糖氧化酶(GOD)对小麦粉糊化特性、动态流变学性质、面团微结构及面筋中氨基酸的影响.研究表明:添加25、50和75 mg/kg葡萄糖氧化酶的面糊的峰值黏度和最终黏度降低,衰减值增大.添加葡萄糖氧化酶的面团弹性模量(G′)和黏性模量(G″)增加.在给定频率下,面团弹性模量大于黏性模量;添加葡萄糖氧化酶面团面筋网络结构增强,淀粉颗粒镶嵌于面筋网络;面筋蛋白质氨基酸含量发生变化.     

模糊控制强化生物除磷SBR系统的除磷过程

采用在线ORP和pH仪对两个平行的强化生物除磷(EBPR)SBR反应系统的厌氧放磷、缺氧吸磷和好氧吸磷过程进行监测。针对聚糖菌(GAO)和聚磷菌(PAO)的竞争和影响PAO和反硝化聚磷菌(DPAO)的各种因素,验证了以氧化还原电位(ORP)和pH作为除磷过程模糊控制参数的可行性和有效性。在此基础上,确立了厌氧／好氧(A／O)SBR系统和厌氧／缺氧(A2)SBR系统除磷过程的模糊控制策略。对ORP和pH的在线检测不仅可以模糊控制厌氧放磷、缺氧吸磷和好氧吸磷过程所需时间,节约能源优化处理效果,而且可以指示系统运行效果和功能微生物种群的竞争行为。     

Influence of Temperature on the Colloidal Stability of Polymer‐Coated Gold Nanoparticles in Cell Culture Media

The temperature‐dependence of the hydrodynamic diameter and colloidal stability of gold‐polymer core‐shell particles with temperature‐sensitive (poly(N‐isopropylacrylamide)) and temperature‐insensitive shells (polyallylaminine hydrochloride/polystyrensulfonate, poly(isobutylene‐alt‐maleic anhydride)‐graft‐dodecyl) are investigated in various aqueous media. The data demonstrate that for all nanoparticle agglomeration, i.e., increase in effective nanoparticle size, the presence of salts or proteins in the dispersion media has to be taken into account. Poly(N‐isopropylacrylamide) coated nanoparticles show a reversible temperature‐dependent increase in size above the volume phase transition of the polymer shell when they are dispersed in phosphate buffered saline or in media containing protein. In contrast, the nanoparticles coated with temperature‐insensitive polymers show a time‐dependent increase in size in phosphate buffered saline or in medium containing protein. This is due to time‐dependent agglomeration, which is particularly strong in phosphate buffered saline, and induces a time‐dependent, irreversible increase in the hydrodynamic diameter of the nanoparticles. This demonstrates that one has to distinguish between temperature‐ and time‐induced agglomerations. Since the size of nanoparticles regulates their uptake by cells, temperature‐dependent uptake of thermosensitive and non‐thermosensitive nanoparticles by cells lines is compared. No temperature‐specific difference between both types of nanoparticles could be observed.     

F单体与高分子量PAN共混的酸性可染腈纶的染色性能研究

报道了F单体与高分子量PAN共混制备的酸性可染腈纶对酸性染料的染色性能,讨论了染色温度、pH值、时间、盐的百分含量对该酸性可染腈纶上染率的影响.正交试验证实:染色温度的影响最显著,染色时间的影响其次,盐的用量及染浴pH值的影响最小.正交试验确定的最佳工艺条件为:强酸性染料的最佳工艺条件是:染色温度100 ℃,pH值3,染色时间60 min,盐的用量10%;弱酸性染料的最佳工艺条件是:染色温度100 ℃,pH值5,染色时间60 min,盐的用量10%.     

羊毛硫化染料生态染色工艺的研究

依据羊毛纤维的特点及硫化染料的特性,研究了硫化染料用于羊毛染色的应用,拓展了硫化染料的应用范围.通过对采用不同pH值、还原剂种类、还原剂用量及盐进行染色实验,选择葡萄糖作为还原剂,确定了较理想的染色工艺条件.     

乙酰水杨酸对番茄果实内各部位糖分含量的影响

采用不同浓度乙酰水杨酸处理番茄果实,对在不同发育阶段果实各部位组织中的糖分含量变化进行了测定,结果表明:在番茄果实不同发育期,果实果皮、胶质胎座和心室隔壁中果糖、葡萄糖和蔗糖含量均表现不同程度的增加,但对果实维管束中糖分含量影响不大,说明乙酰水杨酸具有提高番茄糖分含量的作用。     

Neuronal ApoE Regulates the Cell-to-Cell Transmission of α-Synuclein

The presence of protein inclusions, called Lewy bodies (LBs) and Lewy neurites (LNs), in the brain is the main feature of Parkinson’s disease (PD). Recent evidence that the prion-like propagation of α-synuclein (α-syn), as a major component of LBs and LNs, plays an important role in the progression of PD has gained much attention, although the molecular mechanism remains unclear. In this study, we evaluated whether neuronal ApoE regulates the cell-to-cell transmission of α-syn and explored its molecular mechanism using in vitro and in vivo model systems. We demonstrate that neuronal ApoE deficiency attenuates both α-syn uptake and release by downregulating LRP-1 and LDLR expression and enhancing chaperone-mediated autophagy activity, respectively, thereby contributing to α-syn propagation. In addition, we observed that α-syn propagation was attenuated in ApoE knockout mice injected with pre-formed mouse α-syn fibrils. This study will help our understanding of the molecular mechanisms underlying α-syn propagation.     

miR-199a: A Tumor Suppressor with Noncoding RNA Network and Therapeutic Candidate in Lung Cancer

Lung cancer is the leading cause of cancer death worldwide. miR-199a, which has two mature molecules: miR-199a-3p and miR-199a-5p, plays an important biological role in the genesis and development of tumors. We collected recent research results on lung cancer and miR-199a from Google Scholar and PubMed databases. The biological functions of miR-199a in lung cancer are reviewed in detail, and its potential roles in lung cancer diagnosis and treatment are discussed. With miR-199a as the core point and a divergence outward, the interplay between miR-199a and other ncRNAs is reviewed, and a regulatory network covering various cancers is depicted, which can help us to better understand the mechanism of cancer occurrence and provide a means for developing novel therapeutic strategies. In addition, the current methods of diagnosis and treatment of lung cancer are reviewed. Finally, a conclusion was drawn: miR-199a inhibits the development of lung cancer, especially by inhibiting the proliferation, infiltration, and migration of lung cancer cells, inhibiting tumor angiogenesis, increasing the apoptosis of lung cancer cells, and affecting the drug resistance of lung cancer cells. This review aims to provide new insights into lung cancer therapy and prevention.