Macrophage Immunomodulation Through New Polymers that Recapitulate Functional Effects of Itaconate as a Power House of Innate Immunity

Itaconate (ITA) is an emerging powerhouse of innate immunity with therapeutic potential that is limited in its ability to be administered in a soluble form. A library of polyester materials that incorporate ITA into polymer backbones resulting in materials with inherent immunoregulatory behavior is developed. Harnessing hydrolytic degradation release from polyester backbones, ITA polymers result in the mechanism specific immunoregulatory properties on macrophage polarization in vitro. In a functional assay, the polymer-released ITA inhibits bacterial growth on acetate. Translation to an in vivo model of biomaterial associated inflammation, intraperitoneal injection of ITA polymers demonstrate a rapid resolution of inflammation in comparison to a control polymer silicone, demonstrating the value of sustained biomimetic presentation of ITA.     

人工免疫原理在网络入侵检测系统中的研究

文章分析了人工免疫系统的原理,简单建立了一种基于否定选择算法的网络入侵检测系统,引入了一种用于异常事件识别的r-字符块匹配规则,并对规则存在的漏洞进行了分析。     

An Improved Immune Genetic Algorithm for Solving the Optimization Problems of Computer Communication Networks

1　IntroductionIndesigningacomputercommunicationnet work ,thenetworkaveragedelayisanimportantpa rameterinthenetworkperformance .Inthispaper,weonlyconsiderM /M/1networks,whichmeansthatthemessageprocessingtimeisaprobabilisticdensityfunctionwithnegativepower,thegroupar rivalandsendingisofPoissiondistributionwithasinglequeue .Supposethatthenetworktopologicalstructureandtheestimatesoftheexternaltrafficrequirementsaregiven ,howtoselecttheoptimalroutestobeusedbythecommunicatingnodesinthenetworksoast…     

土工合成材料在防汛抢险中的应用

土工合成材料具有整体性强、抢险速度快、适应性强、储运方便、造价低、经久耐用和可废物利用的优点，在防汛抢险中主要起到排水、反滤和防渗的作用，常用于堤岸崩塌、基础管涌、堤身跌窝与漏洞、背水坡散浸、背水面脱坡、洪水浸顶和防风浪淘刷、涵闸及堵口等方面，可及时排队险情。     

An immune oriented multi-agent system for biological image processing

In this article, we present a parallel image processing system based on the concept of reactive agents. Our system lies in the oRis language, which allows to describe finely and simply the agents’ behaviors to detect image features. We also present a method of segmentation using a multi-agent system, and two biological applications made with oRis. The stopping of this multi-agent system is implemented through a technique issued from immunology: the apoptosis.     

关于S盒的几点注记

分析了Ｓ盒的平衡性，相关免疫性，严格雪崩性和非线性度的各种可能定义及它们之间的相互关系，提出了要Ｓ盒采用这些准则的定义。     

Induction of immune tolerance with heart-thymus composite allotransplantation in rats

Objective To study on the role of thymus transplantation for heart allograft in rats. Methods Vascularized heart-thymus combined transplantation was performed with microsurgical technique. Graft survival, histopathology, level of IL-2, IL-4 and its mRNA expression in serum and cardiac grafts were investigated. Results Heart-thymus combined transplantation achieved effect in the prolongation of cardiac graft survival with short-term administration of cyclosporine. Conclusions Vascularized thymus transplantation induced immune tolerance in thymectomized rats.     

福州市档案馆消防设计

本文介绍了甲级档案馆消防设计,探讨了在我国目前档案馆建设中如何选择经济适用的灭火系统,并提出了有关设计规范间存在互为矛盾的问题。     

基于免疫算法的Hopfield神经网络多用户检测器

提出的基于免疫算法的Hopfield神经网络多用户检测器，将扰乱的Hopfield神经网络多用户检测器的输出作为免疫算法的初始种群，利用了免疫算法的全局收敛的特点，从而克服了Hopfield易收敛到局部能量最小点的缺点。理论分析和仿真结果表明：该检测器具有良好的抗多址干扰和抗远近效应的能力。     

激光引信及其在海防导弹上的应用前景

简述了 GaAs 激光器、光电探测器及激光引信的基本特点。说明了激光引信在海防导弹上应用的可行性。提出了为满足掠海导弹的需求所必须解决的关键技术和实施途径。展望了激光引信在导弹控制和导引等方面的应用前景。