Behavioral Phenotype of the Reeler Mutant Mouse: Effects of Reln Gene Dosage and Social Isolation.

Reeler (rl/rl) and reeler/wild-type (+/rl) mice synthesize Reln at subnormal rates, as do patients with schizophrenia, bipolar disorder, and autism, thereby forming the basis for a Reln hypothesis for vulnerability to these psychopathologies and justifying attention to the behavioral phenotypes of Reln-deficient mice. Tests of gait, emotionality, social aggression, spatial working memory, novel-object detection, fear conditioning, and sensorimotor reflex modulation revealed the behavioral phenotype of rl/rl, but not +/rl, mice to be different from that of wild-type (+/+) mice. These results reveal no effect of Reln gene dosage and provide significant challenges to both the Reln and the neurodevelopmental hypotheses of the etiology of major psychopathologies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

住宅建筑结构中隔震技术的应用和经济评价

对当前隔震系统做了简单介绍 ,介绍了基础隔震的技术和施工方法等。讨论在住宅结构中推广隔震技术的方法 ,对各种类型的住宅结构做经济评价 ,讨论推广的可能性和难点。     

Walk－off型光隔离器的隔离度和插入损耗分析

本文介绍了与偏振无关的ｗａｌｋ－ｏｆｆ型光隔离器的原理和结构，从理论和实验两方面分析了影响隔离度和插入损耗的因素，定量计算了加工、调整误差、消光比等对隔离度和插损的限制，给光隔离器的选材、加工和调整提供了依据。     

1μm宽硅深槽刻蚀技术

介绍了硅深槽刻蚀的基本原理和影响刻蚀效果的几个主要工艺因素。提出了一种实现１μｍ宽的硅深槽刻蚀工艺途径；并给出了１μｍ宽、８μｍ深、侧壁及底部光洁的硅深槽刻蚀工艺条件。     

浅谈多层建筑的斜屋面结构设计

多层建筑的斜屋面结构，应建立合理的结构模型，选用合理的结构方案，在采用结构软件设计时，一定要正确采用倾斜构件沿水平或垂直方向的荷载。     

企业网络隔离方案探讨

分析威胁网络安全的主要因素及网络隔离对网络风险的防范作用。根据几种网络隔离技术的特点和企业网的应用需求，提出企业网中3个典型网络边界上的网络隔离方案，展望网闸隔离技术在企业网中的应用前景。     

声波在多层介质中传播的四端参数模型应用分析研究

声波在两种介质的交界面透射和反射时 ,借鉴机械四端参数法 ,利用声学边界条件 ,引入了四端参数矩阵 ,建立四端参数模型。通过对四端参数矩阵的分析 ,探讨了在简谐平面波垂直入射的条件下 ,声波在多层介质中的传播特性 ,并推导出声透射系数和声反射系数的一般计算公式。     

Isolation and preliminary characterization of Pichia pinus mutants insensitive to glucose repression

A new method for the isolation of glucose repression-insensitive mutants in the methylotrophic yeast Pichia pinus was developed. The method is based on screening of small suspension samples derived from 2-deoxyglucose-resistant colonies for alcohol oxidase activity. Alcohol oxidase activity was evaluated by determination of formaldehyde excreted by cells. Mutants with glucose non-repressible alcohol oxidase and catalase synthesis were obtained. All mutants grew poorly on D -xylose compared to the wild type, whereas growth on L -arabinose was similar to the wild type. Changes in the glucose transport system were suggested to be responsible for altered growth characteristics and defective glucose repression.     

TOPSwitch集成电路在DC/DC电源设计中的应用

文章介绍了PWM／MOSFET二合一的TOPSwitch系列集成电路及其在DC／DC电源设计中的应用，还介绍了基本反馈方式的DC／DC拓扑结构及其改进措施，并对由TOPSwitch集成电路构成的DC／DC电源进行了抗中子实验。