全文获取类型
收费全文 | 3346篇 |
免费 | 485篇 |
国内免费 | 53篇 |
专业分类
电工技术 | 4篇 |
综合类 | 39篇 |
化学工业 | 1065篇 |
金属工艺 | 46篇 |
机械仪表 | 44篇 |
建筑科学 | 13篇 |
能源动力 | 23篇 |
轻工业 | 2263篇 |
水利工程 | 3篇 |
石油天然气 | 8篇 |
无线电 | 51篇 |
一般工业技术 | 272篇 |
冶金工业 | 24篇 |
原子能技术 | 4篇 |
自动化技术 | 25篇 |
出版年
2024年 | 40篇 |
2023年 | 147篇 |
2022年 | 311篇 |
2021年 | 317篇 |
2020年 | 196篇 |
2019年 | 220篇 |
2018年 | 197篇 |
2017年 | 182篇 |
2016年 | 175篇 |
2015年 | 155篇 |
2014年 | 156篇 |
2013年 | 196篇 |
2012年 | 165篇 |
2011年 | 149篇 |
2010年 | 116篇 |
2009年 | 100篇 |
2008年 | 101篇 |
2007年 | 86篇 |
2006年 | 104篇 |
2005年 | 109篇 |
2004年 | 76篇 |
2003年 | 83篇 |
2002年 | 61篇 |
2001年 | 54篇 |
2000年 | 45篇 |
1999年 | 40篇 |
1998年 | 54篇 |
1997年 | 37篇 |
1996年 | 31篇 |
1995年 | 30篇 |
1994年 | 27篇 |
1993年 | 29篇 |
1992年 | 22篇 |
1991年 | 18篇 |
1990年 | 6篇 |
1989年 | 9篇 |
1988年 | 3篇 |
1986年 | 5篇 |
1985年 | 9篇 |
1984年 | 4篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 4篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1978年 | 4篇 |
1976年 | 1篇 |
排序方式: 共有3884条查询结果,搜索用时 31 毫秒
81.
82.
83.
Development of a long‐life vacuum‐packaged ready‐to‐eat meat product based on a traditional Portuguese seasoned meat
下载免费PDF全文
![点击此处可从《International Journal of Food Science & Technology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Marta Laranjo Ana Gomes Maria Eduarda Potes Maria José Fernandes Maria João Fraqueza Miguel Elias 《International Journal of Food Science & Technology》2016,51(5):1150-1158
Carne do alguidar is a Portuguese traditional pork fried meat, usually manufactured for self‐consumption purposes. This study developed a ready‐to‐eat (RTE) meat product, to meet today's consumers’ convenience, manufactured at the industrial scale evaluating its quality and shelf life, assessing the effect of vacuum packaging and the use of an antioxidant (50 ppm BHT) to enhance oxidative stability. Physicochemical and microbiological parameters were assessed, and a sensory analysis was performed. Interestingly, no significant differences were recorded between control (non‐BHT) and antioxidant (BHT) samples. Microbiological counts remained at low levels throughout the storage period, ensuring the product's required microbiological quality. At later storage stages, higher values of thiobarbituric acid‐reactive substances arose and off flavours and aromas were perceived. Still, overall appreciation was not affected until 12 months of storage and a significant depreciation was perceived only after 15 months. Fibrousness and rising of off flavours were negatively correlated with overall appreciation. 相似文献
84.
Anna F. Horn Nina S. Nielsen Charlotte Jacobsen 《International Journal of Food Science & Technology》2012,47(5):1097-1108
The objective of this study was to investigate the protective effect of five different emulsifiers on iron‐mediated lipid oxidation in 70% fish oil‐in‐water emulsions. The emulsifiers were either based on protein (whey protein isolate and sodium caseinate) or based on phospholipid (soy lecithin and two milk phospholipids with different phospholipid contents, MPL20 and MPL75). Lipid oxidation was studied at pH 4.5 and 7.0, and results were compared to lipid oxidation in neat fish oil. Results showed that all emulsions oxidised more than neat oil. Furthermore, emulsions prepared with proteins oxidised more at low pH than at high pH, and casein emulsions oxidised the least (Peroxide value (PV) at day 7 was 0.5–0.7 meq kg?1). Among emulsions prepared with phospholipids, emulsions with MPL75 were the most oxidised followed by emulsions prepared with lecithin and MPL20. Thus, PV in MPL75 emulsions was 5.0–5.5 meq kg?1 at day 7 compared with 0.9–1.9 meq kg?1 in MPL20 emulsions. 相似文献
85.
Byung‐Sung Park Sang‐O Park 《International Journal of Food Science & Technology》2016,51(12):2512-2519
The ingestion of egg has been reported to lower blood cholesterol, but the mechanism is unclear. Here, the biochemical metabolic mechanism by which the oral administration of egg yolk affects blood lipid reduction was investigated using normal rats. Blood triglycerides and total cholesterol were lower and high‐density lipoprotein cholesterol was higher in an egg yolk‐given group compared to other groups, while low‐density lipoprotein cholesterol was increased in the pork belly oil‐given group. HMG‐CoA reductase activity was higher in the pork belly oil‐given group, compared to an egg yolk‐given group, a weekly alternating administration of pork belly oil and egg yolk‐given group, and the saline‐given normal control group. However, faecal excretions of total sterol, neutral sterol and acid sterol in an egg yolk‐given group were higher compared to the pork belly oil‐given group, a weekly alternating administration of pork belly oil and egg yolk‐given group, and a normal control group. The results suggested that ingestion of egg decreased blood lipids. 相似文献
86.
Zahra Bakhtiary Jaleh Barar Ayuob Aghanejad Amir Ata Saei Elhameh Nemati 《Drug development and industrial pharmacy》2017,43(8):1244-1253
Non-small cell lung cancer (NSCLC) patients with sensitizing mutations in the exons 18–21 of the epithelial growth factor receptor (EGFR) gene show increased kinase activity of EGFR. Hence, tyrosine kinase inhibitors (TKIs) such as erlotinib (ETB) have commonly been used as the second line therapeutic option for the treatment of metastatic NSCLC. While the ETB is available as an oral dosage form, the local delivery of this TKI to the diseased cells of the lung may ameliorate its therapeutic impacts. In the current study, we report on the development of ETB-loaded solid lipid nanoparticle (SLN) based formulation of dry powder inhaler (ETB-SLN DPI). ETB-SLNs were formulated using designated amount of compritol/poloxamer 407. The engineered ETB-SLNs showed sub-100?nm spherical shape with an encapsulation efficiency of 78.21%. MTT assay and DAPI staining revealed that the ETB-SLNs enhanced the cytotoxicity of cargo drug molecules in the human alveolar adenocarcinoma epithelial A549 cells as a model for NSCLC. To attain the ETB-SLN DPI, the ETB-SLNs were efficiently spray dried into microparticles (1–5?μm) along with mannitol. The ETB-SLN DPI powder displayed suitable flowability and aerodynamic traits. The Carr's Index, Hausner ratio and Next Generation Impactor (NGI) analyses confirmed deep inhalation pattern of the formulation. Based on these findings, we propose the ETB-SLN DPI as a promising treatment modality for the NSCLC patients. 相似文献
87.
Ben Kent Taavi Hunt Tamim A. Darwish Thomas Hau? Christopher J. Garvey Gary Bryant 《Journal of the Royal Society Interface》2014,11(95)
Trehalose, a natural disaccharide with bioprotective properties, is widely recognized for its ability to preserve biological membranes during freezing and dehydration events. Despite debate over the molecular mechanisms by which this is achieved, and that different mechanisms imply quite different distributions of trehalose molecules with respect to the bilayer, there are no direct experimental data describing the location of trehalose within lipid bilayer membrane systems during dehydration. Here, we use neutron membrane diffraction to conclusively show that the trehalose distribution in a dioleoylphosphatidylcholine (DOPC) system follows a Gaussian profile centred in the water layer between bilayers. The absence of any preference for localizing near the lipid headgroups of the bilayers indicates that the bioprotective effects of trehalose at physiologically relevant concentrations are the result of non-specific mechanisms that do not rely on direct interactions with the lipid headgroups. 相似文献
88.
Man‐Li Zhao Jiang‐Ning Hu Xue‐Mei Zhu Hong‐Yan Li Jing Li Ya‐Wei Fan Ze‐Yuan Deng 《International Journal of Food Science & Technology》2014,49(2):453-459
Medium‐ and long‐chain triacylglycerols (MLCTs)–enriched structured lipid (SL) was synthesised through enzymatic interesterification from Cinnamomum camphora seed oil (CCSO) and camellia oil (CO) using Lipozyme RM IM from Rhizomucor miehei as a biocatalyst. Effects of different reaction conditions including substrate molar ratio, reaction time and reaction temperature were investigated. Results showed that 55.81% of total MLCT species (CCO/LaCL, LaCO/LCL, COO/OCO and LaOO/OLaO) was obtained in the interesterified product under the optimal conditions of substrate molar ratio of 1:1.5 (CCSO/CO) at 60 °C for 3 h. Thereafter, fatty acid profiles, tocopherol contents and physiochemical characteristics of the interesterified product and physical blend were comparatively investigated. The fatty acid composition of the interesterified product consisted of capric acid (26.33%), lauric acid (21.29%) and oleic acid (42.33%). It should be mentioned that the interesterified product contained predominantly oleic acid (88.69%) at Sn‐2 position, while MCFAs (68.05%) at Sn‐1,3 positions. Compared with physical blend, the reduction in tocopherol contents and changes of physiochemical characteristics occurred in SL. The smoke point of the interesterified product was much higher than that of the physical blend, which meant that such MLCTs‐enriched SL could be better for cooking purpose. 相似文献
89.
Roghayeh Abbasalipourkabir Aref Salehzadeh Rasedee Abdullah 《Journal of Experimental Nanoscience》2016,11(3):161-174
An in vitro study was conducted to determine the apoptosis induced by tamoxifen (TAM) and TAM-loaded solid lipid nanoparticles (SLNs) in breast cancer cell lines, MCF-7 and MDA-MB231 cells. The effect of free drug and drug-loaded SLN on the cell lines was characterised by cell morphology and cell cycle distribution using phase contrast microscopy, nuclear morphology and flow cytometry, respectively. The results showed that TAM-loaded SLNs have an equally efficient cytotoxic activity against MCF-7 and MDA-MB231 cells, compared to free TAM, and the half maximal inhibitory concentration (IC50) of TAM-loaded SLNs was generally lower than that of free TAM. In the presence of TAM and TAM-loaded SLN, the viability of the both cells diminishes and the cancer cells lose their normal morphological characteristics, detaches, aggregates and later develops apoptotic bodies. Flow cytometry analysis showed that TAM-loaded SLN like the free TAM caused a dose- and time-dependent apoptosis without cell cycle arrest of human breast cancer cells. Therefore, TAM-loaded SLN has great potential in human medicine for the treatment of breast cancers. 相似文献
90.