排序方式: 共有61条查询结果,搜索用时 15 毫秒
41.
利用微乳液胶凝现象来固定化酶是20世纪90年代初建立起来的酶固定化新技术,该技术为胶束酶学在生物合成与转化领域的应用奠定了基础。对微乳液凝胶固定化技术及微乳液凝胶在生物传感器领域的应用做了综述。并对微乳液凝胶技术应用于非水相传感器领域进行了展望。 相似文献
42.
《国际聚合物材料杂志》2012,61(8):430-437
Polymeric organogels based on vinyl phosphonic acid (VPA) and acrylic monomers such as 2-acrylamido 2-methyl propane sulfunic acid (AMPS) and acrylamide (AM) were prepared. The synthesized poly (AMPS-VPA) organgels can absorb ethanol (12.64–31.2 g/g) and methanol (17.65–32.32 g/g). Poly (AM-VPA) can absorb DMSO (4.05–8.94 g/g). TGA analysis showed that thermal stability of organogels was improved with enhancement of VPA content. This was attributed to presence of phosphorus in the polymer structure. Rheological behavior exhibited that gel strength was decreased with higher VPA content in copolymeric structures. 相似文献
43.
《Drug development and industrial pharmacy》2013,39(5):550-556
Objective: The present investigation was aimed at optimizing of estradiol (E2) loaded l-amino acid derivatives organogel formulations resulting in improved the high initial release problems and sustained release of E2.Methods: The visco-elastic properties of blank organogels were measured by rheometer. The E2 organogel formulations were optimized using a central composite design. Also, the effect of gelator structure and composition of the gel formulations on release behavior (in vitro and in vivo) had been studied.Results: The change of the gelator structure could affect significantly the stiffness of the implants. The release behavior of gel without N-Methyl-2-pyrrolidinone (NMP) was controlled by gel corrosion only. While the drug release of the gel with NMP was controlled by both corrosion and diffusion. The high initial release problems of the organogels were improved by optimizing the formulations. The system consisting by N-Lauroyl l-lysine methyl ester (LLM) derivative in the oil indicated the lowest initial drug release, showed a much lower blood drug level and maintained a steady state for nearly 1 month.Conclusion: Organogels based on l-lysine methyl ester derivative were ideal carriers for long-term parenteral administration of E2. 相似文献
44.
45.
46.
A simple method for synthesis of novel organogels based on multiwalled carbon nanotubes (MWCNTs) is reported. Three classes of organogels were synthesized by crosslinking polymerization of dodecyl methacrylate with various weight percentages of 1,4‐butanediol dimethacrylate, vinyl‐group‐modified MWCNTs or pristine MWCNTs in the presence of 2,2‐azoisobutyronitrile as initiator. In this reaction, the carbon nanotubes (CNTs) served simultaneously as an adsorbent, a comonomer and a crosslinking agent. The oil‐absorbent containing CNTs showed much higher swelling capacity in oil and organic solvents compared with that without CNTs. Therefore, CNT‐based organogels can be introduced as a promising candidate for environmental protection and oil recovery. © 2012 Society of Chemical Industry 相似文献
47.
Yucheng Zhang Yusen Zhao Dong Wu Jingjing Xue Yu Qiu Michael Liao Qibing Pei Mark S. Goorsky Ximin He 《Advanced materials (Deerfield Beach, Fla.)》2019,31(37)
Metal‐halide perovskites have become appealing materials for optoelectronic devices. While the fast advancing stretchable/wearable devices require stability, flexibility and scalability, current perovskites suffer from ambient‐environmental instability and incompatible mechanical properties. Recently perovskite?polymer composites have shown improved in‐air stability with the protection of polymers. However, their stability remains unsatisfactory in water or high‐humidity environment. These methods also suffer from limited processability with low yield (2D film or beads) and high fabrication cost (high temperature, air/moisture‐free conditions), thereby limiting their device integration and broader applications. Herein, by combining facile photo‐polymerization with room‐temperature in‐situ perovskite reprecipitation at low energy cost, a one‐step scalable method is developed to produce freestanding highly‐stable luminescent organogels, within which CH3NH3PbBr3 nanoparticles are homogeneously distributed. The perovskite‐organogels present a record‐high stability at different pH and temperatures, maintaining their high quantum yields for > 110 days immersing in water. This paradigm is universally applicable to broad choices of polymers, hence casting these emerging luminescent materials to a wide range of mechanical properties tunable from rigid to elastic. With intrinsically ultra‐stretchable photoluminescent organogels, flexible phosphorous layers were demonstrated with > 950% elongation. Rigid perovskite gels, on the other hand, permitted the deployment of 3D‐printing technology to fabricate arbitrary 2D/3D luminescent architectures. 相似文献
48.
Sarah Regina Pereira Camelo Sophie Franceschi Emile Perez Sophie Girod Fullana 《Drug development and industrial pharmacy》2016,42(6):985-997
AbstractThis article proposes solid-like systems from sunflower oil structured with a fibrillar network built by the assembly of 12-hydroxystearic acid (12-HSA), a gelator molecule for an oil phase. The resulting organogels were studied as oral controlled release formulations for a lipophilic drug, Efavirenz (EFV), dissolved in the oil. The effects of the gelator concentration on the thermal properties of the organogels were studied by Differential Scanning Calorimetry (DSC) and showed that drug incorporation did not change the sol–gel–sol transitions. The erosion and drug release kinetics from organogels under conventional (filling gelatin capsules) or multiparticulate (beads obtained by prilling) dosage forms were measured in simulated gastric and intestinal fluids. EFV release profiles were analyzed using model-dependent (curve-fitting) and independent approaches (Dissolution Efficiency DE). Korsmeyer–Peppas was the best fitting release kinetic model based on the goodness of fit, revealing a release mechanism from organogels loaded with EFV different from the simple drug diffusion release mechanism obtained from oily formulations. From organogels, EFV probably diffuses through an outer gel layer that erodes releasing oil droplets containing dissolved EFV into the aqueous medium. 相似文献
49.
The aim of this study was to examine the feasibility of cookies in which the conventional margarine is replaced with an organogel of vegetable oil (VO) and natural wax. New cookies from VO organogels contain no trans fats and much less saturated fats than cookies made with a conventional margarine. To understand the effects of different kinds of waxes, organogels were prepared from 4 different waxes including sunflower wax (SW), rice bran wax (RBW), beeswax, and candelilla wax and properties of cookie dough and cookie were evaluated. To investigate the effects of different VOs on the properties of cookies, 3 VOs including olive oil, soybean oil and flaxseed oil representing oils rich in oleic acid (18:1), linoleic acid (18:2), and linolenic acid (18:3), respectively, were used. Both the wax and VO significantly affected properties of organogel such as firmness and melting behavior shown in differential scanning calorimetry. The highest firmness of organogel was observed with SW and flaxseed oil. Properties of dough such as hardness and melting behavior were also significantly affected by wax and VO while trends were somewhat different from those for organogels. SW and RBW provided greatest hardnesses to cookie dough. However, hardness, spread factor, and fracturability of cookie containing the wax–VO organogel were not significantly affected by different waxes and VOs. Several cookies made with wax–VO organogels showed similar properties to cookies made with a commercial margarine. Therefore, this study shows the high feasibility of utilization of the organogel technology in real foods such as cookies rich in unsaturated fats. 相似文献
50.
Fran?ois?G.?Gandolfo Arjen?Bot Eckhard?Fl?terEmail author 《Journal of the American Oil Chemists' Society》2004,81(1):1-6
Homologous series of fatty alcohols and FA with chain lengths ranging from 16 to 22 carbons were evaluated for their oil-structuring
potential by texture profile analysis (TPA). FA, fatty alcohols, and their mixtures were found to structure sunflower oil
and several vegetable oils at levels as low as 2% (w/w) for the pure ingredients. Mixtures of fatty alcohols and FA with the
same chain lengths, at 5% (w/w) in sunflower oil, showed a synergistic effect below 20°C at the composition ratios of 7∶3
and 3∶7 (w/w). This synergistic effect in the 7∶3 stearyl alcohol/stearic acid mixture was due to effects on the microstructure
of the composite material. The larger number of small crystals observed in the mixture was attributed to effects on the crystallization
kinetics as a result of minimal interfacial tension at the specific 1∶3 and 3∶1 molecular ratios. 相似文献