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51.
In this paper we present the results of a simulation study to explore the ability of Bayesian parametric and nonparametric models to provide an adequate fit to count data of the type that would routinely be analyzed parametrically either through fixed-effects or random-effects Poisson models. The context of the study is a randomized controlled trial with two groups (treatment and control). Our nonparametric approach uses several modeling formulations based on Dirichlet process priors. We find that the nonparametric models are able to flexibly adapt to the data, to offer rich posterior inference, and to provide, in a variety of settings, more accurate predictive inference than parametric models. 相似文献
52.
中国传统的思维方式深深地影响了中国传统陶瓷艺术设计,中国传统陶瓷艺术设计的历史脉络清晰,深入到设计思维系统的深层,才有助于我们对当前的陶瓷设计作出有效的转化。现代陶瓷设计的观念是对传统陶瓷文化的延续和发展,深入挖掘传统思维方式的源头活水,才是发展中国现代陶瓷设计的关键。 相似文献
53.
Jantana Tangaromsuk Abhijeet P. Borole Maleeya Kruatrachue Prayad Pokethitiyook 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2008,83(10):1375-1380
BACKGROUND: A single‐stage reactor, in which the growth of bacterial culture, induction of desulfurizing enzymes, and desulfurization reaction are carried out in a single step, was adopted to investigate desulfurization of dibenzothiophene (DBT) at high cell densities. Rhodococcus erythropolis, IGTS8 was used as the biocatalyst. Optimal conditions for bacterial growth and DBT desulfurization were investigated. RESULTS: Optimization of fermentation conditions was necessary to obtain high cell densities including controlling accumulation of acetate. Under optimal operating conditions, the maximum optical density at 600 nm (OD600) was measured to be 26.6 at 118 h of cultivation. When biodesulfurization of DBT in model oil with a high cell density culture of IGTS8 was investigated, accumulation of sulfate was found to limit the extent of desulfurization. A sulfate removal step was added to obtain a single‐stage integrated biodesulfurization process. Sulfate removal was achieved via an aqueous bleed stream and use of a separation unit to recycle the organic phase. CONCLUSION: A proof of principle of a complete system capable of biocatalyst growth, induction, desulfurization and by‐product separation was demonstrated. This system enables simplification of the biodesulfurization process and has potential to lower the operating cost of the bioprocess. Copyright © 2008 Society of Chemical Industry 相似文献
54.
龙潭拱坝坝高90m,砼上坝运输是砼施工过程中的中间环节,控制进度的关键,必须因时因地制宜地选择适当的运输机械和运输方案,使砼运输能做到保质、保量、及时和经济,通过论证比较,结合本工程现实情况,砼上坝运输不采用缆机而采用门机方案. 相似文献
55.
Y. Murat Elin Mehmet Saak 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》1995,63(2):174-180
This paper presents the results of urease immobilization onto methacrylic acid–acrylamide grafted poly(ethyleneterephthalate) fibres. The graft yield strongly affected the maximum activity of the immobilized enzyme up to a value of 70·2%. Higher grafting caused a decline in urease activity and led to the degradation of the fibres. The minor changes observed in Km and Vmax demonstrated that the conformational changes existed during immobilization were not extensive. However, 70·2% methacrylic acid–acrylamide-g-fibres containing urease were more stable towards acidic and alkaline pH, high temperature and storage conditions compared with free enzyme. Apart from the increase in stability to heat inactivation, the initial enzymatic activity of the urease–fibre system remained almost unchanged even after 40 repeated assays corresponding to 10 h of operation in 4 months, indicating the excellent durability of the system. 相似文献
56.
57.
根据我国专利法的原则,在对我国催化重整和芳烃生产专利检索过程和结果进行分析的基础上,阐述了对目前我国催化重整工艺专利市场的几点看法并提出对策。 相似文献
58.
本文研究了浸胶工艺对Nomex蜂窝性能的影响,分析探讨了提高Nomex蜂窝性能及外观质量的途径。研究结果表明:采取新的浸胶工艺制作的Nomex蜂窝,各项性能全面达到法国宇航材料标准。 相似文献
59.
The infrastructure renewal program at MIT consists of a large number of projects with an estimated budget that could approach $1 billion. Infrastructure renewal at the Massachusetts Institute of Technology (MIT) is the process of evaluating and investing in the maintenance of facility systems and basic structure to preserve existing campus buildings. The selection and prioritization of projects must be addressed with a systematic method for the optimal allocation of funds and other resources. This paper presents a case study of a prioritization method utilizing multi-attribute utility theory. This method was developed at MIT's Department of Nuclear Engineering and was deployed by the Department of Facilities after appropriate modifications were implemented to address the idiosyncrasies of infrastructure renewal projects and the competing criteria and constraints that influence the judgment of the decision-makers. Such criteria include minimization of risk, optimization of economic impact, and coordination with academic policies, programs, and operations of the Institute. A brief overview of the method is presented, as well as the results of its application to the prioritization of infrastructure renewal projects. Results of workshops held at MIT with the participation of stakeholders demonstrate the feasibility of the prioritization method and the usefulness of this approach. 相似文献
60.